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#34706365 2021/10/27 To Up
Concordance of Cytological Specimens with Histological Tissue for Detection of Epidermal Growth Factor Receptor Mutation in Non-Small Cell Lung Cancer: A Systematic Review.There is increasing need for more testing in non-small cell lung cancer given the introduction of newer targeted therapies. Cytological specimens including conventional smears (CS), cell blocks (CB), and liquid-based cytology (LBC) are an alternative to histologic tissue (HT) specimens in detecting EGFR mutations, but the concordance of these 2 specimens is yet to be determined. The aim of the present systematic review is to determine the concordance rates between different cytologic specimens with HT in detecting EGFR mutations.
Tzy Harn Chua, Khoon Leong Chuah
1300 related Products with: Concordance of Cytological Specimens with Histological Tissue for Detection of Epidermal Growth Factor Receptor Mutation in Non-Small Cell Lung Cancer: A Systematic Review.
#34706351 2021/10/27 To Up
Directed stimulation with interfascicular interfaces for peripheral nerve stimulation.Computational models have shown that directional electrical contacts placed within the epineurium, between the fascicles, and not penetrating the perineurium, can achieve selectivity levels similar to point source contacts placed within the fascicle. The objective of this study is to test, in a murine model, the hypothesis that directed interfascicular contacts are selective.
Smruta Koppaka, Allison Hess-Dunning, Dustin J Tyler
2384 related Products with: Directed stimulation with interfascicular interfaces for peripheral nerve stimulation.1 kit(96 Wells) 25 G0.1 ml100ug Lyophilized10 lt 1000 ml 25 μg1 g0.2 mg
#34706269 2021/10/24 To Up
Reflected near-infrared light versus bite-wing radiography for the detection of proximal caries: a multicenter prospective clinical study conducted in private practices.The aim of the present prospective multicenter clinical study was to compare the detection of proximal caries with near-infrared light reflection (NILR) versus bitewing radiography (BWR).
Zvi Metzger, Dana G Colson, Peggy Bown, Timo Weihard, Ingo Baresel, Tim Nolting
1759 related Products with: Reflected near-infrared light versus bite-wing radiography for the detection of proximal caries: a multicenter prospective clinical study conducted in private practices.
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#34706218 2021/10/20 To Up
Bidirectional control of infant rat social behavior via dopaminergic innervation of the basolateral amygdala.Social interaction deficits seen in psychiatric disorders emerge in early-life and are most closely linked to aberrant neural circuit function. Due to technical limitations, we have limited understanding of how typical versus pathological social behavior circuits develop. Using a suite of invasive procedures in awake, behaving infant rats, including optogenetics, microdialysis, and microinfusions, we dissected the circuits controlling the gradual increase in social behavior deficits following two complementary procedures-naturalistic harsh maternal care and repeated shock alone or with an anesthetized mother. Whether the mother was the source of the adversity (naturalistic Scarcity-Adversity) or merely present during the adversity (repeated shock with mom), both conditions elevated basolateral amygdala (BLA) dopamine, which was necessary and sufficient in initiating social behavior pathology. This did not occur when pups experienced adversity alone. These data highlight the unique impact of social adversity as causal in producing mesolimbic dopamine circuit dysfunction and aberrant social behavior.
Maya Opendak, Charlis Raineki, Rosemarie E Perry, Millie RincÃ³n-CortÃ©s, Soomin C Song, Roseanna M Zanca, Emma Wood, Katherine Packard, Shannon Hu, Joyce Woo, Krissian Martinez, K Yaragudri Vinod, Russell W Brown, Gerald A Deehan, Robert C Froemke, Peter A Serrano, Donald A Wilson, Regina M Sullivan
1196 related Products with: Bidirectional control of infant rat social behavior via dopaminergic innervation of the basolateral amygdala.N/A 5 GBox of 10 vials for 500 m1000 assays1 vial500120 ml
#34706145 2021/10/27 To Up
Artificial Intelligence in Clinical and Translational Science: Successes, Challenges and Opportunities.Artificial intelligence (AI) is transforming many domains including finance, agriculture, defense and biomedicine. In this paper, we focus on the role of AI in clinical and translational research (CTR) including pre-clinical research (T1), clinical research (T2), clinical implementation (T3) and public (or population) health (T4). Given the rapid evolution of AI in CTR, we present three complementary perspectives: 1) scoping literature review, 2) survey, and 3) analysis of federally-funded projects. For each CTR phase, we addressed challenges, successes, failures and opportunities for AI. We surveyed Clinical and Translational Science Award (CTSA) hubs regarding AI projects at their institutions. Nineteen of 63 CTSA hubs (30%) responded to the survey. The most common funding source (48.5%) was the federal government. The most common translational phase was T2 (clinical research, 40.2%). Clinicians were the intended users in 44.6% of projects and researchers in 32.3% of projects. The most common computational approaches were supervised machine learning (38.6%) and deep learning (34.2%). The number of projects steadily increased from 2012 to 2020. Finally, we analyzed 2,604 AI projects at CTSA hubs using the National Institutes of Health Research Portfolio Online Reporting Tools (RePORTER) database for 2011-2019. We mapped available abstracts to Medical Subject Headings and found that nervous system (16.3%) and mental disorders (16.2) were the most common topics addressed. From a computational perspective, big data (32.3%) and deep learning (30.0%) were most common. This work represents a snapshot in time of the role of AI in the CTSA program.
Elmer V Bernstam, Paula K Shireman, Funda Meric-Bernstam, Meredith Zozus, Xiaoqian Jiang, Bradley B Brimhall, Ashley K Windham, Susanne Schmidt, Shyam Visweswaran, Ye Ye, Heath Goodrum, Yaobin Ling, Seemran Berapatre, Michael J Becich
2483 related Products with: Artificial Intelligence in Clinical and Translational Science: Successes, Challenges and Opportunities.25 MG100ul
#34706110 2021/10/27 To Up
Antiferromagnetism in Ni-Based Superconductors.Due to the lack of any magnetic order down to 1.7 K in the parent bulk compound NdNiO ; the recently discovered 9-15 K superconductivity in the infinite-layer Nd Sr NiO thin films has provided an exciting playground for unearthing new superconductivity mechanisms. In this letter; we report the successful synthesis of a series of superconducting Nd Sr NiO thin films ranging from 8 to 40Â nm. We observe the large exchange bias effect between the superconducting Nd Sr NiO films and a thin ferromagnetic layer; which suggests the existence of the antiferromagnetic order. Furthermore; the existence of the antiferromagnetic order is evidenced by X-ray magnetic linear dichroism measurements. These experimental results are fundamentally critical for the current field. This article is protected by copyright. All rights reserved.
Xiaorong Zhou, Xiaowei Zhang, Jiabao Yi, Peixin Qin, Zexin Feng, Peiheng Jiang, Zhicheng Zhong, Han Yan, Xiaoning Wang, Hongyu Chen, Haojiang Wu, Xin Zhang, Ziang Meng, Xiaojiang Yu, Mark B H Breese, Jiefeng Cao, Jingmin Wang, Chengbao Jiang, Zhiqi Liu100ug Lyophilized1 mL100ug1 mg100 μg1 Set20 ul (10 mM)100 μg1 Set100 μg1 Set100 μg
#34706050 2021/10/27 To Up
Occurrence of the seven most common serotypes of Shiga toxin-producing Escherichia coli in beef cuts produced in meat-processing plants in the state of SÃ£o Paulo, Brazil.Healthy cattle are considered the main reservoir of Shiga toxin-producing Escherichia coli (STEC) strains, so in some places in the world, products derived from beef are the most common source for disease outbreaks caused by these bacteria. Therefore, in order to guarantee that the beef produced by our slaughterhouses is safe, there is a need for continuous monitoring of these bacteria. In this study, 215 beef cuts were evaluated, including chilled vacuum-packed striploins (151 samples), rib eyes (30 samples), and knuckles (34 samples), from March to June, 2018. These meat samples were collected from the slaughter of unconfined cattle, being arbitrarily collected from eight meat-processing companies in SÃ£o Paulo state, Brazil. Each sample was examined for the presence of STEC toxin type ( stx 1 and/or stx 2 genes) and also the E. coli attaching-and-effacing ( eae ) gene, which were determined by a multiplex PCR assay. Here we show that the major seven STEC strains (O serogroups O26, O45, O103, O111, O121, O145, and O157) are not detected in any of the analyzed beef cut samples; however, three of them presented the virulence eae gene. Therefore, the absence of STEC strains in the beef samples may be an indication of the low prevalence of this pathogen in the cattle herd on the farm, associated with good hygiene and handling practices adopted by the meat industry.
Miriam GonÃ§alves Marquezini, Luis Henrique da Costa, Renata Bromberg
1873 related Products with: Occurrence of the seven most common serotypes of Shiga toxin-producing Escherichia coli in beef cuts produced in meat-processing plants in the state of SÃ£o Paulo, Brazil.1100
#34706033 2021/10/25 To Up
Children's and parents' perceptions concerning surgical attire: a systematic review.To review the literature about children's and parent's perceptions on surgical attire.
Luciana Butini Oliveira, Carla Massignan, Isabel Cristina Quaresma RÃªgo, Maria Marlene de Souza Pires, Bruce Dick, Michele Bolan, Graziela De Luca Canto
1026 related Products with: Children's and parents' perceptions concerning surgical attire: a systematic review.100ug96T100ug50 ug 50 ug 100ug100ug50 ug 100ug
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#34706032 2021/10/25 To Up
Effects of community health worker-based interventions on physical activity levels in children: a systematic review.To identify the strategies and effects of interventions carried out by community health workers (CHW) on physical activity (PA) levels in children and adolescents.
Paulo Henrique Guerra, Rafael Silvestre, Tiago Henrique Toldo de Mello, Ana Luiza Babo Sedlacek Carvalho, Filipe Ferreira da Costa, Alex Antonio Florindo
1069 related Products with: Effects of community health worker-based interventions on physical activity levels in children: a systematic review.48 assays 96T96 assays 48 assays 900 tests96 assays 400Tests100ug
#34706025 2021/10/22 To Up
Range of factors in the reduction of hyperhydricity associated with in vitro shoots of Salvia santolinifolia Bioss.Hyperhydricity is a serious physiological disorder and affects In vitro propagation of many plants and as well of Salvia santolinifolia. The donor material to initiate the in vitro culture was the callus taken from the in vitro shoots produced on Murashig and Skoogs (MS) medium at 4.0 mg/l BA. This callus formed numerous hyperhydric shoots on culturing upon the medium of the same composition. The aim was to systematically evaluate the effect of cytokinins (Benzyladnine (BA) and N6-(-2-isopentenyl) adenine (2iP), culture vessels magnitude, medium solidification, source of nitrogen and calcium chloride for the alleviation of hyperhydricity. In the tissue cultures of S. santolinifolia BA and 2iP induced severe hyperhydricity, when other factors i.e. culture vessels magnitude and a suitable concentration of agar, ammonium nitrate (NH4NO3), potassium nitrate (KNO3) & calcium chloride (CaCl2.2H2O) were not optimized. After 30 days' culture, we observed 83.82% hyperhydric shoots at increased level (1.5 mg/l 2iP) and 81.59% at decreased levels (1.0 mg/l 2iP). On the other hand, hyperhydricity percentage at decreased (0.4%) and at increased (0.8%) levels of agar were 72.37% and 39.08%, respectively. MS medium modification with NH4NO3 (412 mg/l), KNO3 (475 mg/l) and CaCl2.2H2O (880 mg/l) was found the best medium to reduced hyperhydricity (23.6%).
T Jan, S Gul, A Khan, S Pervez, A Noor, H Amin, S Bibi, M A Nawaz, A Rahim, M S Ahmad, R Azam, H Ullah
2868 related Products with: Range of factors in the reduction of hyperhydricity associated with in vitro shoots of Salvia santolinifolia Bioss.5 G50 ug96 tests1mg
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