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#35973803   2022/08/16 To Up

Low-dose interleukin-2 therapy in active systemic lupus erythematosus (LUPIL-2): a multicentre, double-blind, randomised and placebo-controlled phase II trial.

A regulatory T cell (Treg) insufficiency due to shortage of interleukin-2 (IL-2) is central to the pathophysiology of systemic lupus erythematosus (SLE). We performed a multicentre, double-blinded, randomised, placebo-controlled phase II proof-of-concept trial to evaluate the efficacy of low-dose IL-2 therapy in patients with SLE having moderate-to-severe disease activity while receiving standard treatment.
Jens Y Humrich, Patrice Cacoub, Michelle Rosenzwajg, Fabien Pitoiset, Hang Phuong Pham, Joel Guidoux, David Leroux, Thomas Vazquez, Gabriela Riemekasten, Josef S Smolen, George Tsokos, David Klatzmann

2562 related Products with: Low-dose interleukin-2 therapy in active systemic lupus erythematosus (LUPIL-2): a multicentre, double-blind, randomised and placebo-controlled phase II trial.

10 mg100.00 ug1 mg500 100.00 ug 0.1 mg 1 mg100ug Lyophilized100.00 ug200ul500 100.00 ug

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#35973802   2022/08/16 To Up

Association of baseline soluble immune checkpoints with the risk of relapse in PR3-ANCA vasculitis following induction of remission.

We investigated whether soluble immune checkpoints (sICPs) predict treatment resistance, relapse and infections in patients with antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV).
Gabriele Gamerith, Finn Mildner, Peter A Merkel, Kristina Harris, Laura Cooney, Noha Lim, Robert Spiera, Philip Seo, Carol A Langford, Gary S Hoffman, E William St Clair, Fernando C Fervenza, Paul Monach, Steven R Ytterberg, Duvuru Geetha, Arno Amann, Dominik Wolf, Ulrich Specks, John H Stone, Andreas Kronbichler

1190 related Products with: Association of baseline soluble immune checkpoints with the risk of relapse in PR3-ANCA vasculitis following induction of remission.

5 G1-99 mg/ml/ea price x 211-99 mg/ml/ea price x 296T

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#35973779   2022/08/16 To Up

Prospective cohort study on the trajectory and association of perioperative anxiety and postoperative opioid-related outcomes.

Although perioperative anxiety is common, its trajectory and influence on postoperative pain and opioid use are not well understood. We sought to examine the association and trajectory of perioperative anxiety, pain and opioid use following common surgical procedures.
Shay N Nguyen, Afton L Hassett, Hsou-Mei Hu, Chad M Brummett, Mark C Bicket, Noelle E Carlozzi, Jennifer F Waljee

2662 related Products with: Prospective cohort study on the trajectory and association of perioperative anxiety and postoperative opioid-related outcomes.

100.00 ul500 mg25 mg100ug1000 TESTS/0.65ml10 mg1000 200ug25 mg 5 G100ug 5 G

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#35973759   2022/06/26 To Up

Toxicological impact of organophosphorus Chlorpyrifos 48%EC pesticide on hemocytes, biochemical disruption, and molecular changes in Biomphalaria alexandrina snails.

O
Amina M Ibrahim, Ahmed A A Hussein

1465 related Products with: Toxicological impact of organophosphorus Chlorpyrifos 48%EC pesticide on hemocytes, biochemical disruption, and molecular changes in Biomphalaria alexandrina snails.

1 Set5mg100ug100 μg100ug Lyophilized100 100 ul (2 mM)50 µl1 mg5 Inhibitors

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#35973743   // To Up

Peripheral blood T-cell subset and its clinical significance in lupus nephritis patients.

Lupus nephritis (LN) is a common and severe manifestation of SLE. Memory T (TM) cells have been implicated in the pathogenesis of SLE. This study aimed to investigate the clinical significance of T-cell subsets in a cohort of patients with LN.
Huijing Wang, Lan Lan, Jianghua Chen, Liang Xiao, Fei Han

2961 related Products with: Peripheral blood T-cell subset and its clinical significance in lupus nephritis patients.

3x 500 ml2 ml2 Pieces/Box

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#35973736   2022/08/16 To Up

A novel dibenzofuran from endophytic fungus Mycosphaerella nawae preferentially inhibits CD4 T cell activation and proliferation.

To obtain promising immunosuppressants from endophytic fungus.
Li-Wei Wang, Jie Li, Le-Xin Gao, Feng-Yang Chen

2669 related Products with: A novel dibenzofuran from endophytic fungus Mycosphaerella nawae preferentially inhibits CD4 T cell activation and proliferation.

2500 Tests24 tests200 100 ug25 mg0.5 mg25 Tests96T500 assays

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#35973703   2022/08/16 To Up

Promoting psychosocial environments in Norwegian primary schools: a scoping review protocol exploring the roles and responsibilities of school social workers.

Early intervention by identifying children at risk and providing necessary support is vital to prevent stunted psychosocial development and mental health issues. In this regard, schools are important intervention arenas, reaching all students at a universal level. The need for enhanced efforts is well recognised in Norwegian policy documents, whereas school social workers can represent significant roles in supporting teachers with expanded knowledge on psychosocial factors, mental health and relevant interventions. Despite the clearly stated needs for interprofessional competence in school, limited research has been conducted, and there are no national standards or guidelines for school social workers' practice. Thus, this scoping review's overall objectives are to systematically map the existing research on social workers' roles and responsibilities in Norwegian primary schools.
Marianne Tevik Singstad, Fredrik Mørk Røkenes, Stine Margrethe Ekornes

2428 related Products with: Promoting psychosocial environments in Norwegian primary schools: a scoping review protocol exploring the roles and responsibilities of school social workers.