Gentaur Pub

#37438461   2023/07/12 To Up

Impact of thermal oxidation parameters on micro-hardness and hot corrosion of Ti-6Al-3Mo-2Nb-2Sn-2Zr-1.5Cr alloy.

Protective oxide layers on Ti-6Al-3Mo-2Nb-2Sn-2Zr-1.5Cr (TC21) alloy with equiaxed microstructure considerably influence micro-hardness and hot corrosion resistance. The present work's thermal oxidation of TC21 alloy was performed at 600, 700, and 800 °C for 5, 20, and 50 h durations. Hot corrosion methods in NaCl and NaCl + NaSO salt media were applied to raw (unoxidized) and oxidized samples at 600 and 800 °C for 50 h. Hot corrosion was conducted at 600 °C for 5 cycles with 10-h steps. The best oxide layer thickness was observed at 800 °C, which increased with increased oxidation time and temperature. The surface hardness of the oxide layer at 800 °C was 900 ± 60 HV owing to the formation of TiO and AlO phases. Raw material hardness was 342 ± 20 HV, increasing threefold due to thermal oxidation. In the case of NaCl, weight loss dominated all samples except at 800 °C for 5 h. In the case of NaCl + NaSO, weight gain occurred at 600 and 800 °C for 5 h. Weight loss occurred for the raw samples and those processed at 800 °C for 20 and 50 h, where the oxide layer flaked off. Surface hardness increased upon hot corrosion testing because of the formation of brittle phases, such as TiO and NaTiO. Samples that oxidized at 800 °C for 5 h had the highest hardness and corrosion resistance.
Fathy S Ahmed, Mohamed A El-Zomor, Magdy S Abo Ghazala, Ramadan N Elshaer

2872 related Products with: Impact of thermal oxidation parameters on micro-hardness and hot corrosion of Ti-6Al-3Mo-2Nb-2Sn-2Zr-1.5Cr alloy.

5 G 6 ml Ready-to-use 10 mg0.2 mg1000U; 5U/ul1000 tests120 micro gram20000 (in case - Bulk)100ug500 mg

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#36944750   2023/03/21 To Up

Modeling of wear resistance for TC21 Ti-alloy using response surface methodology.

This study investigated the effect of heat treatment processes on the dry sliding wear resistance of the TC21 Ti-alloy at several levels of normal load and sliding speed. Response Surface Methodology (RSM) has been used as a design of the experiment procedure. OM and FESEM besides XRD analysis were used for results justification. Highest hardness of 49 HRC was recorded for WQ + Aging specimens due to the plenty of α″ which decomposed to α and the more α, while the lowest hardness of 36 HRC was reported for WQ specimens. The results revealed that specimens subjected to water quenching and aging (WQ + Aging) under extreme load and speed conditions (50 N and 3 m/s), possessed the poorest wear resistance although they had the highest hardness. While those left in the annealed condition revealed the highest wear resistance although they had much lower hardness when compared to other conditions. A mathematical polynomial model for wear resistance expressed in wear rate was developed, validated then used to get the optimum parameters.
Ali Abdelmoneim, Ramadan N Elshaer, M El-Shennawy, Arafa S Sobh

2858 related Products with: Modeling of wear resistance for TC21 Ti-alloy using response surface methodology.

100ug100 mg10 mg96T5 g100μg100 µg 100ul

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• Aging \ 53185 \ WP2313

#36476833   2022/12/07 To Up

Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors.

The R-RAS2 GTP hydrolase (GTPase) (also known as TC21) has been traditionally considered quite similar to classical RAS proteins at the regulatory and signaling levels. Recently, a long-tail hotspot mutation targeting the R-RAS2/TC21 Gln residue (Q72L) was identified as a potent oncogenic driver. Additional point mutations were also found in other tumors at low frequencies. Despite this, little information is available regarding the transforming role of these mutant versions and their relevance for the tumorigenic properties of already-transformed cancer cells. Here, we report that many of the RRAS2 mutations found in human cancers are highly transforming when expressed in immortalized cell lines. Moreover, the expression of endogenous R-RAS2 is important for maintaining optimal levels of PI3K and ERK activities as well as for the adhesion, invasiveness, proliferation, and mitochondrial respiration of ovarian and breast cancer cell lines. Endogenous R-RAS2 also regulates gene expression programs linked to both cell adhesion and inflammatory/immune-related responses. Endogenous R-RAS2 is also quite relevant for the in vivo tumorigenic activity of these cells. This dependency is observed even though these cancer cell lines bear concurrent gain-of-function mutations in genes encoding RAS signaling elements. Finally, we show that endogenous R-RAS2, unlike the case of classical RAS proteins, specifically localizes in focal adhesions. Collectively, these results indicate that gain-of-function mutations of R-RAS2/TC21 play roles in tumor initiation and maintenance that are not fully redundant with those regulated by classical RAS oncoproteins.
Laura Clavaín, Isabel Fernández-Pisonero, Nieves Movilla, L Francisco Lorenzo-Martín, Blanca Nieto, Antonio Abad, Rósula García-Navas, Clara Llorente-González, Manuel Sánchez-Martín, Miguel Vicente-Manzanares, Eugenio Santos, Balbino Alarcón, José M García-Aznar, Mercedes Dosil, Xosé R Bustelo

1885 related Products with: Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors.

5 G11 Set

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#36357445   2022/11/10 To Up

Effect of oxide layers formed by thermal oxidation on mechanical properties and NaCl-induced hot corrosion behavior of TC21 Ti-alloy.

In the current study on TC21 Ti-alloy (6.5Al-3Mo-1.9Nb-2.2Sn-2.2Zr-1.5Cr), the thermal oxidation formed oxide layers that considerably influenced mechanical properties (hardness and wear). TC21 specimens were oxidized at 600, 700, 800, and 900 °C for 5, 20, and 50 h. NaCl-induced hot corrosion testing was carried out on raw (un-oxidized) and oxidized specimens at 600 and 800 °C for 50 h. The cyclic testing was performed at 600 °C for durations of 5, 10, 20, 30, 40, and 50 h. The average thickness of the layer grew with increasing oxidation time and temperature. A thin oxide layer (average 0.16 µm) was generated by oxidation at a temperature of 600 °C for a duration of 5 h, and at 800 °C, a large oxide layer of 10.8 µm thickness was formed. The most significant surface hardness of 1000 ± 150 HV was produced for the layer oxidized at 900 °C. On the other hand, the lowest hardness of 360 ± 150 HV was recorded for the raw materials. Best wear resistance had been achieved for specimens oxidized at 800 °C. During NaCl hot corrosion test, the weight loss of the raw specimen was 6.4 mg/cm due to the flaking off of the corrosion product. However, for specimens oxidized at 600 °C for 50 h, weight loss after corrosion testing was 0.54 mg/cm, less than that of the specimen before corrosion. Oxidized specimens at 800 °C exhibited the best mechanical characteristics and corrosion resistance.
Fathy S Ahmed, Mohamed A El-Zomor, Magdy S Abo Ghazala, Ramadan N Elshaer

2919 related Products with: Effect of oxide layers formed by thermal oxidation on mechanical properties and NaCl-induced hot corrosion behavior of TC21 Ti-alloy.

5 G1 mg1,000 tests 100ul200ug 6 ml Ready-to-use 1000U; 5U/ul1 mg1 mg0.2 mg2 x 96 assays2.5 mg

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#35683166   2022/05/28 To Up

In Situ Tensile Deformation and Mechanical Properties of α Platelets TC21 Alloy.

The present study was focused on the relationship between an α platelet microstructure and the properties of TC21 alloy, and the tensile deformation process was revealed by in situ observation. To obtain the α platelet microstructures, the samples were administered a solution treatment (1000 °C for 15 min) and then cooled to room temperature by different cooling methods (furnace cooling (FC), open-door furnace cooling (OFC), air cooling (AC), and water quench (WQ), corresponding to an increased cooling rate). It is found that α platelets become thinner and colonies become narrower with the increase in cooling rate. The formation of the platelet microstructure is based on the preferred Burgers orientation relationship of {110}β//{0001}α and <111>β//<112¯0>α. The α platelets orientation changes with the cooling rate. These differences in α platelets thickness and orientation result in the excellent ductility of the sample with thick platelets and the high strength of the samples with thin platelets. During the in situ tensile deformation process, the crack propagation path is deflected in the presence of grain boundaries, α platelets, and α colonies with different orientations. The fracture of the sample with thick α platelets shows better ductility compared to those with thin α platelets.
Chunlin Yang, Song Zhang, Meigui Ou

1891 related Products with: In Situ Tensile Deformation and Mechanical Properties of α Platelets TC21 Alloy.

1 Set1 Set1 Set0.1ml1 mg200ul100 μg100.00 ug50100 μg

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#35307520   2022/03/17 To Up

Integrated meta-omics study on rapid tylosin removal mechanism and dynamics of antibiotic resistance genes during aerobic thermophilic fermentation of tylosin mycelial dregs.

For efficient treatment of tylosin mycelial dregs (TMDs), rapid tylosin removal mechanism and dynamics of ARGs during TMDs fermentation were investigated using integrated meta-omics (genomics, metaproteomics and metabolomics) and qPCR approaches. The results showed that over 86% of tylosin was degraded on day 7 regardless of the type of bulking agents. The rapid removal of tylosin was mainly attributed to de-mycarose reaction (GH3) and esterase hydrolysis (C7MYQ7) of Saccharomonospora, and catalase-peroxidase oxidation of Bacillus (A0A077JB13). In addition, the moisture content and mobile genetic elements were vital to control the rebound of ARGs. The removal efficiency of antibiotic resistant bacteria (Streptomyces, Pseudomonas, norank_f__Sphingobacteriaceae, and Paenalcaligenes) and Intl1 (98.8%) in fermentation treatment TC21 with corncob as the bulking agent was significantly higher than that in other three treatments (88.3%). Thus, appropriate bulking agents could constrain the abundance of antibiotic resistant bacteria and Intl1, which is crucial to effectively reduce the resistance.
Guomeng Sha, Lili Zhang, Xiuyun Wu, Tong Chen, Xiaohong Tao, Xin Li, JianGuo Shen, Guanjun Chen, Lushan Wang

1539 related Products with: Integrated meta-omics study on rapid tylosin removal mechanism and dynamics of antibiotic resistance genes during aerobic thermophilic fermentation of tylosin mycelial dregs.

1 mL5mg1 g 5 G5 g5mg500 mg25 ml 2 ml 400Tests5mg

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#35269151   2022/03/04 To Up

Hot Deformation and Constitutive Modeling of TC21 Titanium Alloy.

Titanium alloys are extensively employed in the fabrication of various aviation structural parts, of which the most crucial processing step is hot working. In order to study the high-temperature deformation behavior of the TC21 titanium alloy, high-temperature tensile tests were performed. The results reveal that the flow stress of the material gradually decreases with an increased strain rate, and the stress increases rapidly with an increase in strain during the deformation of the alloy. Following this, flow stress gradually decreases. Flow stress decreases sharply, and the sample fractures when the appearance of necking and microvoids is observed. The Arrhenius and Radial basis function (RBF) neural network constitutive models are established in order to accurately describe the high-temperature deformation behavior of the material. In the modified Arrhenius model, strain rate indexes are expressed as a function of deformation temperature and strain rates; furthermore, the high prediction ability of the model was obtained. For the Radial basis function, the network parameters were obtained using the trial-and-error method. The established models could better forecast the flow stress of materials, and highly accurate results are obtained using the radial basis function model. The relationships between the stress index and the deformation activation energy with strain indicate that the primary deformation mechanism involves grain boundary slip and viscous slip of dislocations. The process of dynamic recrystallization primarily promotes the softening of the material.
Sheng-Xian Yi, Zhong-Jiong Yang, Huang-Xin Xie

2680 related Products with: Hot Deformation and Constitutive Modeling of TC21 Titanium Alloy.

10 mg0.1 mg100 mg50 ul96T100ug250ul1 mg1000 tests

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#34777306   2021/10/27 To Up

Microbial Diversity Analysis and Genome Sequencing Identify as the Pathogen of Bacterial Leaf Canker of Water Spinach ().

is a leafy vegetable widely cultivated in tropical Asia, Africa, and Oceania. Bacterial leaf canker disease has been attacking the planting fields and seriously affecting the quality of in epidemic areas in China. This study examined the microbial composition of leaves with classical symptoms of spot disease. The results showed that was overwhelmingly dominant in all four diseased leaf samples but rarely present in rhizospheric soil or irrigation water samples. In addition, was also detected in two of the diseased leaf samples. Pathogen isolation, identification, and inoculation revealed that both sp. TC2-1 and were pathogenic to the leaves of , causing crater-shaped ulcerative spots and yellowing with big brown rot lesions on leaves, respectively. We further sequenced the whole genome of strain TC2-1 and showed that it is a member of . Overall, this study identified as the causal pathogen of bacterial leaf canker, and as a companion pathogen causing yellowing and brown rot on leaves. The correct identification of the pathogens will provide important basis for future efforts to formulate targeted application strategy for bacterial disease control.
Ming Hu, Chuhao Li, Xiaofan Zhou, Yang Xue, Si Wang, Anqun Hu, Shanshan Chen, Xiuwen Mo, Jianuan Zhou

2374 related Products with: Microbial Diversity Analysis and Genome Sequencing Identify as the Pathogen of Bacterial Leaf Canker of Water Spinach ().

1 KIT1 5 G100μl100 Plates100 tests100 assays200 assays200 assays

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#34649269   2021/10/14 To Up

Cutting mechanism of straight-tooth milling process of titanium alloy TC21 based on simulation and experiment.

Due to the characteristics of high strength, high chemical activity and low heat conduction, titanium alloy materials are generally difficult to machine. As a typical titanium alloy with higher strength and lower heat conductivity, the machinability of titanium alloy TC21 is very poor and its cutting process is companied with larger cutting force and rapid tool wear. Straight-tooth milling tool is often used to cut the groove and side surface in the titanium alloy parts. And the milling method can be used to investigate the cutting mechanism because the cutting force has only two components and the better chip morphology is obtained. To investigate the straight-tooth milling process of TC21 alloy, a series of milling force experiments have been done. In addition, a 3D finite element model (FEM) for the straight-tooth milling process of TC21 alloy is presented to simulate the milling process. In the model, the constitutive material model, the failure model, the friction model and the heat transfer model were adopted. Through the simulation, chip formation, stress distribution, cutting force and milling temperature were obtained. The cutting force reaches its maximum when the spindle speed reaches about 13000 rpm, and then decreases as the speed continues to increase. The results confirmed that the similar "Salomon" phenomenon existed in the cutting process of TC21 alloy.
Zhang Lei, Lei Pei

1687 related Products with: Cutting mechanism of straight-tooth milling process of titanium alloy TC21 based on simulation and experiment.

5mg 5 G5mg2.5 mg10mg100ug0.1 mg5mg5mg10 mg 25 ml Ready-to-use 5mg

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#34577780   2021/09/07 To Up

Erratum: Elshazli et al. Laser Surface Modification of TC21 (α/β) Titanium Alloy Using a Direct Energy Deposition (DED) Process. 2021, , 739.

In the original article [...].
Ahmed Magdi Elshazli, Ramadan N Elshaer, Abdel Hamid Ahmed Hussein, Samar Reda Al-Sayed

1622 related Products with: Erratum: Elshazli et al. Laser Surface Modification of TC21 (α/β) Titanium Alloy Using a Direct Energy Deposition (DED) Process. 2021, , 739.

10 mg10 mg48 samples0.2 mg100 μg1 mg100 mg250 mg10 mg1 g100 μg100 μg

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