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Search results for: Troponin

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#33098469   2020/10/24 To Up

Elevated high-sensitivity troponin T levels at 1-year follow-up are associated with increased long-term mortality after TAVR.

Elevated pre-procedural high-sensitivity troponin T (hs-TnT) levels predict adverse outcomes in patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR). It is unknown whether elevated troponin levels still provide prognostic information during follow-up after successful TAVR. We evaluated the long-term implications of elevated hs-TnT levels found at 1-year post-TAVR.
Hatim Seoudy, Moritz Lambers, Vincent Winkler, Linnea Dudlik, Sandra Freitag-Wolf, Johanne Frank, Christian Kuhn, Ashraf Yusuf Rangrez, Thomas Puehler, Georg Lutter, Peter Bramlage, Norbert Frey, Derk Frank

1367 related Products with: Elevated high-sensitivity troponin T levels at 1-year follow-up are associated with increased long-term mortality after TAVR.

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#33098411   2020/10/24 To Up

Atrial nitroso-redox balance and refractoriness following on-pump cardiac surgery: A randomised trial of atorvastatin.

Systemic inflammation and increased activity of atrial NOX2-containing NADPH oxidases have been associated with the new onset of atrial fibrillation (AF) after cardiac surgery. In addition to lowering LDL-cholesterol, statins exert rapid anti-inflammatory and antioxidant effects, the clinical significance of which remains controversial.
Raja Jayaram, Michael Jones, Svetlana Reilly, Mark J Crabtree, Nikhil Pal, Nicola Goodfellow, Keshav Nahar, Jillian Simon, Ricardo Carnicer, Ravi DeSilva, Chandana Ratnatunga, Mario Petrou, Rana Sayeed, Andrea Roalfe, Keith M Channon, Yaver Bashir, Timothy Betts, Michael Hill, Barbara Casadei

2830 related Products with: Atrial nitroso-redox balance and refractoriness following on-pump cardiac surgery: A randomised trial of atorvastatin.

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#33098365   2020/10/24 To Up

Prognostic value of pre-treatment cardiovascular biomarkers in head and neck squamous cell carcinoma.

To examine the prognostic significance of pre-treatment C-reactive protein (CRP), N-terminal pro-brain natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) levels on all-cause mortality three years after head and neck squamous cell carcinoma (HNSCC) diagnosis.
Karine Gadioli de Oliveira, Marcela Marçal Thebit, Tadeu Uggere Andrade, Fabiana Vasconcelos Campos, Jose Roberto Vasconcelos Podestá, Sandra Lucia Ventorin Von Zeidler, Nazaré Souza Bissoli, Sonia Alves Gouvea

1032 related Products with: Prognostic value of pre-treatment cardiovascular biomarkers in head and neck squamous cell carcinoma.



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#33098053   2020/10/24 To Up

Searching for Preclinical Models of Acute Decompensated Heart Failure: a Concise Narrative Overview and a Novel Swine Model.

Available animal models of acute heart failure (AHF) and their limitations are discussed herein. A novel and preclinically relevant porcine model of decompensated AHF (ADHF) is then presented.
Davide Olivari, Daria De Giorgio, Lidia Irene Staszewsky, Francesca Fumagalli, Antonio Boccardo, Deborah Novelli, Martina Manfredi, Giovanni Babini, Anita Luciani, Laura Ruggeri, Aurora Magliocca, Davide Danilo Zani, Serge Masson, Angelo Belloli, Davide Pravettoni, Giuseppe Maiocchi, Roberto Latini, Giuseppe Ristagno

1519 related Products with: Searching for Preclinical Models of Acute Decompensated Heart Failure: a Concise Narrative Overview and a Novel Swine Model.

50 mg 1 G100ug Lyophilized250ug25 mg 100 G1 mg100ug96T100ug

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#33095801   2020/10/23 To Up

The impact of lockdown enforcement during the SARSCoV-2 pandemic on the timing of presentation and early outcomes of patients with ST-elevation myocardial infarction.

Early reports described decreased admissions for acute cardiovascular events during the SarsCoV-2 pandemic. We aimed to explore whether the lockdown enforced during the SARSCoV-2 pandemic in Israel impacted the characteristics of presentation, reperfusion times, and early outcomes of ST-elevation myocardial infarction (STEMI) patients.
Ofer Kobo, Roi Efraim, Majdi Saada, Natalia Kofman, Ala Abu Dogosh, Yigal Abramowitz, Doron Aronson, Sa'ar Minha, Ariel Roguin, Simcha R Meisel

2506 related Products with: The impact of lockdown enforcement during the SARSCoV-2 pandemic on the timing of presentation and early outcomes of patients with ST-elevation myocardial infarction.

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#33094648   2020/10/23 To Up

Can Glypican-6 Level Predict Ejection Fraction Decline After Myocardial Infarction?

The main goals in the treatment of acute coronary syndrome are to prevent myocardial ischemia, damage, and possible complications. Accordingly, we evaluated the predictive value of glypican-6 (GPC6) for cardiac remodeling after myocardial infarction (MI). Baseline plasma GPC6 levels were measured in patients who underwent primary percutaneous coronary intervention (PCI) for acute MI. Left ventricular ejection fraction (LVEF) was measured at baseline and at 6 months with transthoracic echocardiography. Reduced LVEF persisted in 89 out of 276 patients after 6 months. The majority of the patients were male (n = 198, 72%) and the mean age was 57.8 ± 10.8 years. Glypican-6, N-terminal pro-brain natriuretic peptide (NT-proBNP), and high-sensitive troponin levels were significantly lower in the improved LVEF group compared with the low LVEF group (10.54 ± 4.46 vs 6.98 ± 3.34 ng/mL, < .001; 500 pg/mL [range, 300-600 pg/mL] vs 350 pg/mL [range, 200-550 pg/mL], = .008; 396 pg/mL [range, 159-579 pg/mL] vs 300 pg/mL [range, 100-500 pg/mL], = .016, respectively). Logistic regression analysis revealed the SYNTAX Score 2, GPC6, and NT-proBNP as significant independent predictors of low LVEF (hazard ratio [HR]: 1.064, = .041; HR: 1.215, < .001; HR: 1.179, < .001). Glypican-6 may prove to be useful for the detection of low LVEF development in patients undergoing PCI following MI.
Fatih Ozturk, Adem Atici, Hasan Ali Barman

2653 related Products with: Can Glypican-6 Level Predict Ejection Fraction Decline After Myocardial Infarction?

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#33094161   2020/02/21 To Up

NT-proBNP Level Predicts Extent of Myonecrosis and Clinical Adverse Outcomes in Patients with ST-Elevation Myocardial Infarction: A Pilot Study.

The initial assessment of late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR) reflects cardiac damage and is an important prognostic factor in patients with acute ST-elevation myocardial infarction (STEMI). N-Terminal prohormone of brain natriuretic peptide (NT-proBNP) is released following cardiomyocytes injury. However, the relationship between NT-proBNP levels, myocardial damage and clinical outcomes after STEMI has not been well defined.
Mohammad Mathbout, Ahmed Asfour, Steve Leung, Georges Lolay, Amr Idris, Ahmed Abdel-Latif, Khaled M Ziada

2090 related Products with: NT-proBNP Level Predicts Extent of Myonecrosis and Clinical Adverse Outcomes in Patients with ST-Elevation Myocardial Infarction: A Pilot Study.



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