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#33096587   2020/10/23 To Up

Dental pain in homeless adults in Porto Alegre, Brazil.

To evaluate the association of dental pain with time living on the street in a sample of homeless people in the city of Porto Alegre, Brazil.
Marcela Obst Comassetto, Fernando Neves Hugo, Matheus Neves, Juliana Balbinot Hilgert

1592 related Products with: Dental pain in homeless adults in Porto Alegre, Brazil.

10mg100ug100ug1.00 flask1 Set100 μg100.00 ug1 Set100 μg

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#33096525   2020/10/23 To Up

Use of a novel ball-joint guide array for magnetic resonance imaging-guided cannula placement and convective delivery: technical note.

The objective of this study was to assess the feasibility, accuracy, effectiveness, and safety of an MRI-compatible frameless stereotactic ball-joint guide array (BJGA) as a platform for cannula placement and convection-enhanced delivery (CED).
Krystof S Bankiewicz, Tomasz Pasterski, Daniel Kreatsoulas, Jakub Onikijuk, Krzysztof Mozgiel, Vikas Munjal, J Bradley Elder, Russell R Lonser, Mirosław Zabek

1081 related Products with: Use of a novel ball-joint guide array for magnetic resonance imaging-guided cannula placement and convective delivery: technical note.



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#33096040   2020/10/17 To Up

Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses.

Polyreactivity is the ability of a single antibody to bind to multiple molecularly distinct antigens and is a common feature of antibodies induced upon pathogen exposure. However, little is known about the role of polyreactivity during anti-influenza virus antibody responses. By analyzing more than 500 monoclonal antibodies (mAbs) derived from B cells induced by numerous influenza virus vaccines and infections, we found mAbs targeting conserved neutralizing influenza virus hemagglutinin epitopes were polyreactive. Polyreactive mAbs were preferentially induced by novel viral exposures due to their broad viral binding breadth. Polyreactivity augmented mAb viral binding strength by increasing antibody flexibility, allowing for adaption to imperfectly conserved epitopes. Lastly, we found affinity-matured polyreactive B cells were typically derived from germline polyreactive B cells that were preferentially selected to participate in B cell responses over time. Together, our data reveal that polyreactivity is a beneficial feature of antibodies targeting conserved epitopes.
Jenna J Guthmiller, Linda Yu-Ling Lan, Monica L Fernández-Quintero, Julianna Han, Henry A Utset, Dalia J Bitar, Natalie J Hamel, Olivia Stovicek, Lei Li, Micah Tepora, Carole Henry, Karlynn E Neu, Haley L Dugan, Marta T Borowska, Yao-Qing Chen, Sean T H Liu, Christopher T Stamper, Nai-Ying Zheng, Min Huang, Anna-Karin E Palm, Adolfo García-Sastre, Raffael Nachbagauer, Peter Palese, Lynda Coughlan, Florian Krammer, Andrew B Ward, Klaus R Liedl, Patrick C Wilson

2497 related Products with: Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses.

100 extractions96T30ml600 Tests / Kit100ul5 g50ml30 m Pcs Per Pack50ml1015ml

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#33095904   2020/10/23 To Up

Stimulated GH levels during the transition phase in Prader-Willi syndrome.

Early institution of GH therapy in children with Prader-Willi syndrome (PWS) yields beneficial effects on their phenotype and is associated with a persistent improvement of body composition, both in the transition age and in adulthood. Reports from GH stimulation testing in PWS adults, however, suggest that GH deficiency (GHD) is not a universal feature of the syndrome, and the current Consensus Guidelines suggest to perform a reassessment of persistent GHD so as to continue GH therapy after reaching adult height. Few data about GH responsiveness to stimulation testing throughout the transitional period in PWS are available to date. Thus, we investigated the prevalence of GHD in a large cohort of patients with PWS during the transition phase.
G Grugni, P Marzullo, M Delvecchio, L Iughetti, M R Licenziati, S Osimani, L Ragusa, A Salvatoni, A Sartorio, S Stagi, A Crinò,

2547 related Products with: Stimulated GH levels during the transition phase in Prader-Willi syndrome.

100 μg1100ug Lyophilized

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#33095865   2020/10/23 To Up

Temporal Detection Limits of Remnant Larval Bloodmeals in Nymphal Ixodes scapularis (Say, Ixodida: Ixodidae) Using Two Next-Generation Sequencing DNA Barcoding Assays.

Using next-generation sequencing DNA barcoding, we aimed to determine: 1) if the larval bloodmeal can be detected in Ixodes scapularis nymphs and 2) the post-moult temporal window for detection of the larval bloodmeal. Subsets of 30 nymphs fed on a domestic rabbit (Oryctolagus cuniculus Linnaeus, Lagomorphia: Leporidae) as larvae were reared and frozen at 11 time points post-moult, up to 150 d. Vertebrate DNA was amplified using novel universal (UP) and species-specific primers (SSP) and sequenced for comparison against cytochrome c oxidase subunit I barcodes to infer host identification. Detectable bloodmeals decreased as time since moult increased for both assays. For the SSP assay, detection of bloodmeals decreased from 96.7% (n = 29/30) in day 0 nymphs to 3.3% (n = 1/30) and 6.7% (n = 2/30) at 4- and 5-mo post-moult, respectively. A shorter temporal detection period was achieved with the UP assay, declining from 16.7% (n = 5/30) in day 0 nymphs to 0/30 in 3-d-old nymphs. Bloodmeal detection was nonexistent for the remaining cohorts, with the exception of 1/30 nymphs at 2-mo post-moult. Host detection was significantly more likely using the SSP assay compared to the UP assay in the first three time cohorts (day 0: χ 2 = 39.1, P < 0.005; day 2: χ 2 = 19.2, P < 0.005; day 3: χ 2 = 23.3, P < 0.005). Regardless of the primer set used, the next-generation sequencing DNA barcoding assay was able to detect host DNA from a larval bloodmeal in the nymphal life stage; however, a short window with a high proportion of detection post-moult was achieved.
Genevieve A M Lumsden, Evgeny V Zakharov, Sarah Dolynskyj, J Scott Weese, L Robbin Lindsay, Claire Jardine

1666 related Products with: Temporal Detection Limits of Remnant Larval Bloodmeals in Nymphal Ixodes scapularis (Say, Ixodida: Ixodidae) Using Two Next-Generation Sequencing DNA Barcoding Assays.

96 assays 100 assays100 assays25 assays100 assays100 assays50 assays48 assays

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#33095710   2020/10/23 To Up

Universal Adversarial Attack on Attention and the Resulting Dataset DAmageNet.

Adversarial attacks on deep neural networks (DNNs) have been found for several years. However, the existing adversarial attacks have high success rates only when the information of the victim DNN is well-known or could be estimated by the structure similarity or massive queries. In this paper, we propose to Attack on Attention (AoA), a semantic feature commonly shared by DNNs. AoA enjoys a significant increase in transferability when the traditional cross entropy loss is replaced with the attention loss. Since AoA alters the loss function only, it could be easily combined with other transfer-based attacks and then achieve SOTA performance. We apply AoA to generate 50000 adversarial samples from ImageNet validation set to defeat many neural networks, and thus name the dataset as DAmageNet. 13 well-trained DNNs are tested on DAmageNet, all of them have an error rate over 85%. Even with defenses or adversarial training, most models still maintain an error rate over 70% on DAmageNet. DAmageNet is the first universal adversarial dataset and it may serve as a benchmark for robustness testing and adversarial training.
Sizhe Chen, Zhengbao He, Chengjin Sun, Jie Yang, Xiaolin Huang

1007 related Products with: Universal Adversarial Attack on Attention and the Resulting Dataset DAmageNet.

100ug1 25 ml Ready-to-use 100 mg200 units1 mg1 kit1000 tests100 1000 TESTS/0.65ml

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#33095574   2020/10/23 To Up

Bistriazoles with a Biphenyl Core Derivative as an Electron-Favorable Bipolar Host of Efficient Blue Phosphorescent Organic Light-Emitting Diodes.

High-quality host materials are indispensable for the construction in the emitting layer of efficient organic light-emitting diodes (OLEDs), especially in a guest and host system. The good carrier transport and energy transfer between the host and emitters are out of necessity. In this work, a wide bandgap and bipolar organic compound, 2,2'-bis(4,5-diphenyl-(1,2,4)-triazol-3-yl)biphenyl (), conjugating two electron-transporting triazole moieties on a hole-transporting biphenyl core, was synthesized and characterized. The wide bandgap of 4.0 eV makes the promise in efficient energy transfer between the host and various color emitters to apply as the universal host, especially for blue emitters. The close electron and hole mobilities perform the same order of 10 cm·V·s, identified as bipolar behavior and benefited for carrier balance at low bias. Although carrier transportation belongs to bipolar behavior at a low electrical field, the electron mobility is much faster than the hole one at a high electrical field and belongs to electron-transporting behavior. Employing the as the host matrix mixed with a phosphor dopant, iridium(III)bis[4,6-di-fluorophenyl-pyridinato-N,C]picolinate, a high-efficiency sky-blue phosphorescent organic light-emitting diode (OLED) was achieved with a maximum current efficiency of 65.9 cd/A, maximum power efficiency of 62.8 lm/W, and maximum external quantum efficiency of 30.2%.
Jiun-Haw Lee, Chia-Hsun Chen, Bo-Yen Lin, Yi-Hsin Lan, Yi-Mei Huang, Nai-Jing Chen, Jau-Jiun Huang, Dmytro Volyniuk, Rasa Keruckiene, Juozas Vidas Grazulevicius, Yuh-Renn Wu, Man-Kit Leung, Tien-Lung Chiu

1690 related Products with: Bistriazoles with a Biphenyl Core Derivative as an Electron-Favorable Bipolar Host of Efficient Blue Phosphorescent Organic Light-Emitting Diodes.

50 ug 50 ug 0.1ml500 ug50 ug 100 ug 50 ug 50 ug

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#33095561   2020/10/23 To Up

Bioinspired Color-Changeable Organogel Tactile Sensor with Excellent Overall Performance.

Inspired by chameleons' structural color regulation capability, a simple, but effective, swelling method is proposed for the first time to prepare an ionic polyacrylamide (PAAm) organogel for simultaneous tactile sensing and interactive color changing. The PAAm organogel obtained by swelling the PAAm scaffold in the dimethyl sulfoxide solution of organic electrochromic material (OECM) shows an extremely large stretchability with an elongation of 1600%, a supersoftness with a compressive modulus of 7.2 kPa, an excellent transmittance up to 90%, and a very fast response time of 0.5 s combined with the characteristic of interactive color changing. The PAAm organogel also suggests a universal design ability to tailor coloration spectra for tactile sensors via simply changing the type and content of OECM. The tactile sensor based on a PAAm organogel is capable of serving as a wearable device for precisely tracing human body motion performance and directly visualizing the stress distribution via interactive color changing capability. It is demonstrated that the swelling method proposed here is a simple and practical strategy to prepare ionic organogels with both piezo-resistive and electrochromic effects.
Ya-Feng Liu, Qun Liu, Jun-Fei Long, Feng-Lian Yi, Yuan-Qing Li, Xiao-Hua Lei, Pei Huang, Bing Du, Ning Hu, Shao-Yun Fu

2808 related Products with: Bioinspired Color-Changeable Organogel Tactile Sensor with Excellent Overall Performance.

1 kit132/kit1 kit1 kit66/kit480/kit1 kit1 kit120/kit400/kit1 kit

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