Only in Titles

Search results for: WB

paperclip

#32789755   2020/08/13 To Up

Detection of distant metastases in rectal cancer: contrast-enhanced CT vs whole body MRI.

To evaluate the diagnostic performance of whole-body MRI (WB-MRI) including contrast-enhanced T1-weighted imaging (T1WI) and WB-DWI in rectal cancer initial staging.
Jeong Hee Yoon, Mi Hye Yu, Bo Yun Hur, Chang Min Park, Jeong Min Lee

2085 related Products with: Detection of distant metastases in rectal cancer: contrast-enhanced CT vs whole body MRI.

1 Set

Related Pathways

paperclip

#32788114   2020/06/24 To Up

Flow cytometric analysis of platelet function to improve the recognition of thrombocytopathy.

Light transmission aggregometry (LTA) is the gold standard for diagnosing bleeding disorders. Although LTA is laborious, requires large volumes of blood and is relatively insensitive to small changes in platelet function, there is still no competing alternative approach to replace LTA for the diagnosis of platelet bleeding disorders.
Dana Huskens, Li Li, Lisa Florin, Pieter de Kesel, Bas de Laat, Mark Roest, Katrien M J Devreese

1023 related Products with: Flow cytometric analysis of platelet function to improve the recognition of thrombocytopathy.

1 module1 module1 module1 module1 module1 module1 module1 module1 module2 modules2 modules

Related Pathways

paperclip

#32787923   2020/08/12 To Up

Does whole-body bone SPECT/CT provide additional diagnostic information over [18F]-FCH PET/CT for the detection of bone metastases in the setting of prostate cancer biochemical recurrence?

To assess whether whole-body (WB) bone SPECT/CT provides additional diagnostic information over [18F]-FCH PET/CT for the detection of bone metastases in the setting of prostate cancer biochemical recurrence (PC-BR).
Nicolas de Leiris, Julien Leenhardt, Bastien Boussat, Christopher Montemagno, Alexandre Seiller, Olivier Phan Sy, Julie Roux, Mathieu Laramas, Camille Verry, Carole Iriart, Gaelle Fiard, Jean-Alexandre Long, Jean-Luc Descotes, Jean-Philippe Vuillez, Laurent Riou, Loïc Djaileb

1250 related Products with: Does whole-body bone SPECT/CT provide additional diagnostic information over [18F]-FCH PET/CT for the detection of bone metastases in the setting of prostate cancer biochemical recurrence?



Related Pathways

paperclip

#32786856   2020/08/05 To Up

Early Postmortem proteome changes in normal and woody broiler breast muscle.

Early post-mortem changes in the whole muscle proteome from normal (NB) and woody broiler breast (WB) at 0 min, 15 min, 4 h and 24 h after slaughter were analyzed using 2DE and LC-MS/MS. Elongation factor 2, EH domain-containing protein 2, phosphoglycerate mutase 1 (PGAM1) and T-complex protein 1 subunit gamma were differentially abundant in both NB and WB muscles during early post-mortem storage. Twenty additional proteins were differentially abundant among four post-mortem time points in either NB or WB muscles. In post-mortem WB, changes in protein degradation were observed, including desmin fragment, ovotransferrin chain A and troponin I chain I. Additionally, a few glycolytic proteins in WB might have undergone post-translational modification, including enolase, phosphoglucomutase-1, PGAM1 and pyruvate kinase. These changes in protein biomarkers highlight the impact of WB myopathy on post-mortem proteome changes and increase our understanding of the relationship between WB condition, post-mortem biochemistry, and meat quality.
Xue Zhang, Wei Zhai, Shuting Li, Surendranath P Suman, Jing Chen, Haining Zhu, Daniel Antonelo, Mark Wesley Schilling

2859 related Products with: Early Postmortem proteome changes in normal and woody broiler breast muscle.



Related Pathways

paperclip

#32785775   2020/08/12 To Up

Effects of Different Types of Exercise on Bone Mineral Density in Postmenopausal Women: A Systematic Review and Meta-analysis.

In this sub-analysis of a comprehensive meta-analysis, we aimed to determine the effect of different types of exercise on (areal) bone mineral density (BMD) in postmenopausal women. A systematic review of the literature according to the PRISMA statement included (a) controlled trials, (b) with at least one exercise and one control group, (c) intervention ≥ 6 months, (d) BMD assessments at lumbar spine (LS), femoral neck (FN) or total hip (TH), (e) in postmenopausal women. Eight electronic databases were scanned without language restrictions up to March 2019. The present subgroup analysis was conducted as a mixed-effect meta-analysis with "type of exercise" as the moderator. The 84 eligible exercise groups were classified into (a) weight bearing (WB, n = 30) exercise, (b) (dynamic) resistance exercise (DRT, n = 18), (c) mixed WB&DRT interventions (n = 36). Outcome measures were standardized mean differences (SMD) for BMD-changes at LS, FN and TH. All types of exercise significantly affect BMD at LS, FN and TH. SMD for LS average 0.40 (95% CI 0.15-0.65) for DRT, SMD 0.26 (0.03-0.49) for WB and SMD 0.42 (0.23-0.61) for WB&DRT. SMD for FN were 0.27 (0.09-0.45) for DRT, 0.37 (0.12-0.62) for WB and 0.35 (0.19-0.51) for WB&DRT. Lastly, SMD for TH changes were 0.51 (0.28-0.74) for DRT, 0.40 (0.21-0.58) for WB and 0.34 (0.14-0.53) for WB&DRT. In summary, we provided further evidence for the favorable effect of exercise on BMD largely independent of the type of exercise. However, in order to generate dedicated exercise recommendations or exercise guideline, meta-analyses might be a too rough tool.
Wolfgang Kemmler, Mahdieh Shojaa, Matthias Kohl, Simon von Stengel

1828 related Products with: Effects of Different Types of Exercise on Bone Mineral Density in Postmenopausal Women: A Systematic Review and Meta-analysis.

900 tests

Related Pathways

paperclip

#32784680   2020/08/07 To Up

Anticancer and Antiviral Properties of Cardiac Glycosides: A Review to Explore the Mechanism of Actions.

Cardiac glycosides (CGs) have a long history of treating cardiac diseases. However, recent reports have suggested that CGs also possess anticancer and antiviral activities. The primary mechanism of action of these anticancer agents is by suppressing the Na/k-ATPase by decreasing the intracellular K and increasing the Na and Ca. Additionally, CGs were known to act as inhibitors of IL8 production, DNA topoisomerase I and II, anoikis prevention and suppression of several target genes responsible for the inhibition of cancer cell proliferation. Moreover, CGs were reported to be effective against several DNA and RNA viral species such as influenza, human cytomegalovirus, herpes simplex virus, coronavirus, tick-borne encephalitis (TBE) virus and Ebola virus. CGs were reported to suppress the HIV-1 gene expression, viral protein translation and alters viral pre-mRNA splicing to inhibit the viral replication. To date, four CGs (Anvirzel, UNBS1450, PBI05204 and digoxin) were in clinical trials for their anticancer activity. This review encapsulates the current knowledge about CGs as anticancer and antiviral drugs in isolation and in combination with some other drugs to enhance their efficiency. Further studies of this class of biomolecules are necessary to determine their possible inhibitory role in cancer and viral diseases.
Dhanasekhar Reddy, Ranjith Kumavath, Debmalya Barh, Vasco Azevedo, Preetam Ghosh

2180 related Products with: Anticancer and Antiviral Properties of Cardiac Glycosides: A Review to Explore the Mechanism of Actions.

5mg 25 G1 g100 ug100.00 ug1 mg3 modules100ug Lyophilized

Related Pathways

paperclip

#32783132   2020/08/11 To Up

Evaluation of the productive characteristics of the Caqueteño Creole cattle breed.

The objective of this research was to evaluate the productive and reproductive characteristics of the Caqueteño Creole cattle breed. Data was taken from 655 animals organized into 6 groups: group 1 (n = 185), pure Caqueteño Creole cattle breed (Caqueteño); group 2 (n = 34), Caqueteño Creole cattle breed crossing for multiracial animals (Caqueteño 50% × multiracial 50%); group 3 (n = 10) (Caqueteño 75% × Bos indicus 25%); group 4 (n = 56), crossbreed F1 (Bos taurus × B. indicus); group 5 (n = 168), animals with B. taurus percentage greater than 50% (B. taurus > 50%); group 6 (n = 202), animals with B. indicus percentage greater than 50% (B. indicus > 50%). Subsequently were done descriptive statistics and analysis of variance (ANOVA) with the LSD Fisher test (P < 0.05), with the software InfoStat version 2018. A significant difference was found (P < 0.05); in weight at birth (WB), Caqueteño presented the smallest value (29.8 kg); in daily weight gain (DWG), weight adjusted at 9 months (W9), and weight adjusted at 18 months (W18), Caqueteño presented highest values corresponding to 574.5 g/day, 183.0 kg, and 343.6 kg, respectively; in age at the first service (AFS), the lowest value was obtained by B. taurus × B. indicus (24.5 months), and in calving interval (CI), no significant differences were found (P > 0.05). In conclusion, the Caqueteño Creole cattle breed is efficient in the productive variables (daily weight gain, adjusted weight at 9 and 18 months); in age at the first service, the F1 group indicated precocity, followed by Caqueteño Creole.
Gustavo Adolfo Celis Parra, Leider Geovany Chinguad Taramuel, Juan Javier Garcia Bustos

2688 related Products with: Evaluation of the productive characteristics of the Caqueteño Creole cattle breed.

10100 IU0.1 mg1500 Units1 ml12

Related Pathways

paperclip

#32783056   // To Up

A review on the woody breast condition, detection methods, and product utilization in the contemporary poultry industry.

In recent years, the global poultry industry has been facing increasing and challenging myopathies such as the woody breast (WB) condition that has caused significant economic losses. Even though the etiological causes of WB myopathy are still unknown or partially understood, the intensive genetic selection for rapid-growth rates and high yields in broilers may be the main factor associated with the development of this abnormality. The severity of this anomaly and its incidence rates are associated with fast-growing and heavier broilers, especially with those from high breast yielding strains. Such WB myopathy is primarily characterized by a notorious hardness in broiler breast muscles, which exhibit morphometric and histopathological alterations coupled with physicochemical abnormalities that result in undesired sensory, nutritional, and technological properties. In this negative context, although scientists are trying to solve or reduce the prevalence of this meat quality problem, the poultry industry needs noncontact and rapid in-line methods for WB detection at the fillet and/or carcass level that could help to establish automated objective grading or sorting systems according to its severity. Another need is the development and selection of profitable alternatives for the utilization of WB meat once poultry carcasses or deboned fillets affected by this abnormality are objectively detected and sorted. Indeed, there is a need for studies to expand the industrial applications of WB meat in further processed products, optimizing the incorporation of this affected chicken meat based on sensorial, technological, and nutritional profile evaluations. Even though a better understanding of the contribution of genetic and nongenetic factors to the development of growth-related myopathies can be the main strategy to mitigate their negative effects, the poultry industry could benefit from meeting the aforementioned needs.
Juan P Caldas-Cueva, Casey M Owens

1908 related Products with: A review on the woody breast condition, detection methods, and product utilization in the contemporary poultry industry.

1100tests

Related Pathways

paperclip

#32782710   2020/07/01 To Up

Fusobacterium nucleatum produces cancer stem cell characteristics via EMT-resembling variations.

To explore the involvement of epithelial-mesenchymal transition (EMT) and cancer stem cell (CSC) characteristics induced by in colorectal cancer (CRC) in vitro.
Qin Wang, Chen Yu, Chao Yue, Xin Liu

2465 related Products with: Fusobacterium nucleatum produces cancer stem cell characteristics via EMT-resembling variations.

1 x 10^6 cells/vial5 x 10A5 cells/vial100 ug1 kit96T3 inhibitors100005005 Modulators1 mg100 ug/vialvial

Related Pathways

paperclip

#32782154   2020/08/08 To Up

Mechanism of TGF-β promoting chondrogenesis in human fat stem cells.

Clinically deficient cartilage is difficult to regenerate, and the availability of chondrocytes is very limited. However, human adipose-derived stem cells (ADSCs) can be obtained easily and in sufficient quantities. Therefore, we will find a way of replacing chondrocytes with fat stem cells to solve the problem of seed cell origin. Previous studies have revealed that transforming growth factor-β (TGF-β) can promote chondrocyte differentiation and maturation. In this study, we found that TGF-β in the transforming growth factor family can effectively promote the transformation process from fat stem cells to chondrocytes, thus promoting chondrogenesis. At the same time, we also further reviewed and considered the mechanism of this process. Through flow cytometry, immunohistochemical, fluorescent microscopy, qRCR, Wb etc., we found that TGF-β mainly plays a role through wnt5a/β-catenin, promoting human fat stem cell growing into the cartilage. This discovery is expected to provide new ideas in the field of cartilage regeneration.
Debao Li, Xiaofei Ma, Tianlan Zhao

1148 related Products with: Mechanism of TGF-β promoting chondrogenesis in human fat stem cells.

1 mg10 ug96 tests1.00 flask1.00 flask3 inhibitors11.00 flask0.1ml (1mg/ml)1.00 flask100 μg100 μg

Related Pathways