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#34563105   2021/09/27 To Up

Subcutaneous regular insulin use for the management of diabetic ketoacidosis in resource limited setting.

The standard recommendation of insulin therapy for patients with DKA is the administration of slow continuous intravenous (IV) regular insulin. Currently subcutaneous insulin is being recommended as an alternative treatment of DKA in mild and moderate cases in resource-limited settings. The purpose of this study was to assess the effectiveness and safety of six-hourly subcutaneous regular insulin use for the treatment of DKA among children with type one diabetes mellitus.
Bereket F Yismaw, Tigist W Leulseged

1478 related Products with: Subcutaneous regular insulin use for the management of diabetic ketoacidosis in resource limited setting.

1 g100ug Lyophilized100ug5 100mg100ug96 wells (1 kit)100ug 1 G250ul100ug100ug Lyophilized

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#34563100   2021/09/25 To Up

A global assessment of recent trends in gastrointestinal cancer and lifestyle-associated risk factors.

Gastrointestinal (GI) cancers were responsible for 26.3% of cancer cases and 35.4% of deaths worldwide in 2018. This study aimed to analyze the global incidence, mortality, prevalence, and contributing risk factors of the 6 major GI cancer entities [esophageal cancer (EC), gastric cancer (GC), liver cancer (LC), pancreatic cancer (PC), colon cancer, and rectal cancer].
Lili Lu, Christina S Mullins, Clemens Schafmayer, Sebastian Zeißig, Michael Linnebacher

1887 related Products with: A global assessment of recent trends in gastrointestinal cancer and lifestyle-associated risk factors.



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#34563095   2021/09/25 To Up

Learnings from two independent malaria elimination demonstration projects in India.

India and sub-Saharan Africa contributes about 85% of the global malaria burden, and India is committed to eliminating malaria by 2030.
Harsh Rajvanshi, Kirti Mishra, Praveen K Bharti, Debakanta Sandhibigraha, Sekh Nisar, Himanshu Jayswar, Aparup Das, Madan M Pradhan, Pradipta K Mohapatra, Pallavi Jain Govil, Nilima Kshirsagar, Aditya P Dash, Shrinath Singh, Ram Shankar Sahu, Harpreet Kaur, Neeraj Dhingra, Azadar Khan, Altaf A Lal

2852 related Products with: Learnings from two independent malaria elimination demonstration projects in India.

100ug500 tests500 tests500 tests100 μg100 ul (2 mM)100 μg50 µl20mg100 μg11 inhibitors100 μg

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#34563057   2021/09/19 To Up

The Language of Dreams: Application of Linguistics-Based Approaches for the Automated Analysis of Dream Experiences.

The study of dreams represents a crucial intersection between philosophical, psychological, neuroscientific, and clinical interests. Importantly, one of the main sources of insight into dreaming activity are the (oral or written) reports provided by dreamers upon awakening from their sleep. Classically, two main types of information are commonly extracted from dream reports: structural and semantic, content-related information. Extracted structural information is typically limited to the simple count of words or sentences in a report. Instead, content analysis usually relies on quantitative scores assigned by two or more (blind) human operators through the use of predefined coding systems. Within this review, we will show that methods borrowed from the field of linguistic analysis, such as graph analysis, dictionary-based content analysis, and distributional semantics approaches, could be used to complement and, in many cases, replace classical measures and scales for the quantitative structural and semantic assessment of dream reports. Importantly, these methods allow the direct (operator-independent) extraction of quantitative information from language data, hence enabling a fully objective and reproducible analysis of conscious experiences occurring during human sleep. Most importantly, these approaches can be partially or fully automatized and may thus be easily applied to the analysis of large datasets.
Valentina Elce, Giacomo Handjaras, Giulio Bernardi

1794 related Products with: The Language of Dreams: Application of Linguistics-Based Approaches for the Automated Analysis of Dream Experiences.

100ul 5 G25 µg2000 IU11 ml500 Units0.1ml (1mg/ml)0.1 mg

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#34563042   2021/08/31 To Up

Neonatal Diabetes in Patients Affected by Liang-Wang Syndrome Carrying KCNMA1 Variant p.(Gly375Arg) Suggest a Potential Role of Ca and Voltage-Activated K Channel Activity in Human Insulin Secretion.

Liang-Wang syndrome (LIWAS) is a polymalformative syndrome first described in 2019 caused by heterozygous mutation of the KCNMA1 gene encoding the Ca and voltage-activated K channel (BKC). The KCNMA1 variant p.(Gly356Arg) abolishes the function of BKC and blocks the generation of K current. The phenotype of this variant includes developmental delay, and visceral and connective tissue malformations. So far, only three cases of LWAS have been described, one of which also had neonatal diabetes (ND). We present the case of a newborn affected by LIWAS carrying the p.(Gly375Arg) variant who manifested diabetes in the first week of life. The description of our case strongly increases the frequency of ND in LIWAS patients and suggests a role of BK inactivation in human insulin secretion. The knowledge on the role of BKC in insulin secretion is very poor. Analyzing the possible mechanisms that could explain the association of LIWAS with ND, we speculate that BK inactivation might impair insulin secretion through the alteration of ion-dependent membrane activities and mitochondrial functions in β-cells, as well as the impaired intra-islet vessel reactivity.
Chiara Mameli, Roberta Cazzola, Luigina Spaccini, Valeria Calcaterra, Maddalena Macedoni, Paola Azzurra La Verde, Enza D'Auria, Elvira Verduci, Gianluca Lista, Gian Vincenzo Zuccotti

2207 related Products with: Neonatal Diabetes in Patients Affected by Liang-Wang Syndrome Carrying KCNMA1 Variant p.(Gly375Arg) Suggest a Potential Role of Ca and Voltage-Activated K Channel Activity in Human Insulin Secretion.

100 μg 100 UG100 μg100 μg100 μg

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#34563007   2021/09/13 To Up

Uterine Epithelioid Trophoblastic Tumor in a 44-Year-Old Woman: A Diagnostic Dilemma.

Epithelioid trophoblastic tumor (ETT) is a rare and newly defined disease, which most commonly occurs in women of reproductive age and can be a sequela of any gestational event. ETT can be present in both intrauterine and extrauterine sites.
Maria-Gabriela Aniţei, Diana-Elena Lazăr, Raluca Alina Pleşca, Cristina Terinte, Radu Iulian, Scripcariu Viorel

2228 related Products with: Uterine Epithelioid Trophoblastic Tumor in a 44-Year-Old Woman: A Diagnostic Dilemma.



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#34563006   2021/09/09 To Up

Exploring Potential COPD Immunosuppression Pathways Causing Increased Susceptibility for MAC Infections among COPD Patients.

Although there has been a drastic decline in the cases of Tuberculosis in the United States, the prevalence of infections caused by Complex (MAC) has steadily increased in the past decades. () is one of the most abundant microorganisms in the MAC species. The mycobacterium genus is divided into two major groups: tuberculosis causing mycobacteria and non-tuberculous mycobacteria. MAC is most prominent among the non-tuberculous mycobacteria. MAC is an opportunistic pathogen that is present in soil, water, and droplets in the air. MAC infections can result in respiratory disease and can disseminate in affected patients. MAC infections are especially prevalent in patients with preexisting respiratory conditions such as Chronic Obstructive Pulmonary Disease (COPD). COPD is one of the most common lung conditions in the world with the primary cause being smoking in developed countries. COPD involves chronic inflammation of lung tissue resulting in increased susceptibility to infection. There is a lack of research regarding the pathophysiology that leads COPD patients to be susceptible to MAC infection. Our review paper therefore aims to investigate how the pathogenicity of MAC bacteria and immune decline seen in COPD patients leads to a greater susceptibility to MAC infection among COPD patients.
Shafaa Munjal, Shalok Munjal, Jingya Gao, Vishwanath Venketaraman

1717 related Products with: Exploring Potential COPD Immunosuppression Pathways Causing Increased Susceptibility for MAC Infections among COPD Patients.

100ul1 kit(96 Wells)10ìg500 ml2x96 well plate2ug 1 G 5 G5ug1 mg 1 G

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#34562994   2021/09/18 To Up

Acute Appendicitis in the Elderly: A Literature Review on an Increasingly Frequent Surgical Problem.

With increased life expectancy and the growing total population of elderly patients, there has been rise in the number of cases of acute appendicitis in elderly people. Although acute appendicitis is not the most typical pathological condition in the elderly, it is not uncommon. Most of these patients require surgical treatment, and as with any acute surgical pathology in advanced age, treatment possibilities are affected by comorbidities, overall health status, and an increased risk of complications. In this literature review we discuss differences in acute appendicitis in the elderly population, with a focus on clinical signs, diagnostics, pathogenesis, treatment, and results.
Sintija Lapsa, Arturs Ozolins, Ilze Strumfa, Janis Gardovskis

2294 related Products with: Acute Appendicitis in the Elderly: A Literature Review on an Increasingly Frequent Surgical Problem.

100ug100ug Lyophilized100 μg100 μg

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#34562988   2021/09/03 To Up

The Spanish Intergenerational Study: Beliefs, Stereotypes, and Metacognition about Older People and Grandparents to Tackle Ageism.

Ageism can be seen as systematic stereotypes, prejudice, and discrimination of people because of their age. For a long time, society has accepted negative stereotypes as a norm. When referring to older adults, the United Nations Global Report on Ageism warns about a severe impact. The Intergenerational Study for a Healthy Aging, a questionnaire about believes, stereotypes, and knowledge about older people and grandparents, was administered to 326 Spanish biology and medical students. Here we report the results of stereotype analysis through adjective qualification of the youth and older people performed before the survey. Content analysis of two open questions about metacognition at the end of the survey is also presented. The results show that: (1) The questionnaire promoted metacognition; (2) Positive metacognition toward grandparents was higher than for the general old population; (3) Most participants were not conscious about ageism; (4) Gender was a key factor-male students were more ageist than females; (5) The feeling of guilt was higher in the questionnaire about older people; (6) The metacognition exercise elicited thoughts and, in few cases, the need to take action to tackle ageism. In conclusion, both activities promoted active thoughts about older people vs. grandparents and helped participants realize unconscious ageism-specifically toward the older population-serving as an awareness activity that may help tackle ageism.
Aida Muntsant, Paula Ramírez-Boix, Rocío Leal-Campanario, Francisco Javier Alcaín, Lydia Giménez-Llort

1977 related Products with: The Spanish Intergenerational Study: Beliefs, Stereotypes, and Metacognition about Older People and Grandparents to Tackle Ageism.

1 mg1,000 tests100ul100ug100 mg1000 tests500 MG25 mg200 10 mg

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