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#32620008   2020/07/03 To Up

Evaluation of Blunt Force Trauma for Culling of Neonatal Piglets On-Farm.

Twenty-seven neonate piglets (range from 0.35 to 1.17 kg) were evaluated for the effectiveness of blunt force trauma as a method of on-farm cull. Brainstem function, brain injury and haemorrhage scores (increasing from 0 to 3) were assessed after striking the head against a concrete floor. Electroencephalograms (EEG) from a subset of 15 piglets were recorded prior to and after blunt force trauma for electrophysiological assessments. Blunt force trauma was performed by a single experienced farmer in a commercial farm by holding the piglet by its both hind legs and striking the head against the concrete floor. All piglets remained recumbent and did not show brainstem reflexes. Only one piglet did not presented tonic/clonic physical activity. The mean time to onset of persistent isoelectric EEG was 64.3 ± 7.3 (range 18 - 115) s. Total power, theta, alpha and beta power decreased to approximately 45%, 30%, 20% and 15% from pre-treatment power, respectively by 15 s post-impact. There were no periods of normal-like EEG after the culling. Bruises in the neck and shoulder were found in 67% and 70% of piglets, respectively. All piglets presented skull fractures with 20% having the nasal bone(s) fractured. Brain damage was found in all piglets, mainly in the frontal lobe(s). The occipital lobe(s) presented the greatest frequency of severe damage. The analysis of the radiographs also found a high frequency of fractures in this region. Haemorrhage was most frequent in the frontal, parietal, occipital lobes and midbrain. When performed correctly with the appropriate weight class, blunt force trauma can be used as an effective method for on-farm killing of nursing piglets resulting in death. However, this method should not be promoted over more reliable and repeatable cull methods such as captive bolt gun (CBG). As with blunt force trauma there is significant potential for animal welfare harm associated with inappropriate practice, lack of accuracy, issues with repeatability and operator fatigue.
Filipe Antonio Dalla Costa, Troy J Gibson, Steffan Edward Octávio Oliveira, Neville George Gregory, Arlei Coldebella, Luigi Faucitano, Charli Beatriz Ludtke, Liziè Peréirã Buss, Osmar Antonio Dalla Costa

1746 related Products with: Evaluation of Blunt Force Trauma for Culling of Neonatal Piglets On-Farm.

5 G1 kit1 mg1 g100 mg 1 G 5 lt

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#32619981   2020/07/03 To Up

Outcomes in single-level posterior cervical spine surgeries performed in the sitting and prone positions.

The sitting or semisitting position in neurosurgery allows for several technical advantages, including improved visualization of the surgical field. However, it has also been associated with an increased risk of venous air embolisms and positioning-related complications that limit its commonplace adoption. The authors report a large, single-center series of cervical spine procedures performed with patients in the sitting or prone position in order to assess the perceived risk of intraoperative and postoperative complications associated with the sitting position.
Benjamin T Himes, Arnoley S Abcejo, Panagiotis Kerezoudis, Adip G Bhargav, Katherine Trelstad-Andrist, Patrick R Maloney, John L D Atkinson, Fredric B Meyer, W Richard Marsh, Mohamad Bydon

2629 related Products with: Outcomes in single-level posterior cervical spine surgeries performed in the sitting and prone positions.



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#32619972   2020/07/03 To Up

Radiographic and clinical outcomes using intraoperative magnetic resonance imaging for transsphenoidal resection of pituitary adenomas.

The utility and safety of intraoperative MRI (iMRI) for resection of pituitary adenomas is not clearly established in the context of advances in endoscopic approaches. The goal in this study was to evaluate the safety and efficacy of iMRI for pituitary adenoma resection, with endoscopic transsphenoidal (ETS) versus microscopic transsphenoidal (MTS) approaches.
Rupa G Juthani, Anne S Reiner, Ankur R Patel, Aimee Cowan, Marie Roguski, Katherine S Panageas, Eliza B Geer, Sasan Karimi, Marc A Cohen, Viviane Tabar

2702 related Products with: Radiographic and clinical outcomes using intraoperative magnetic resonance imaging for transsphenoidal resection of pituitary adenomas.

1L25 mg500 MG25 µg

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#32619928   2020/06/30 To Up

Transoral thyroidectomy (TOETVA): Complications, surgical time and learning curve.

Since 2018, transoral endoscopic thyroidectomy vestibular approach (TOETVA) has emerged as a true scarless thyroid surgery. In this study, we explore early outcomes and learning curve of this new approach.
Renan Bezerra Lira, Andressa Teruya Ramos, Ricardo Miguel Ribeiro Nogueira, Genival Barbosa de Carvalho, Jonathon O Russell, Ralph P Tufano, Luiz Paulo Kowalski

1574 related Products with: Transoral thyroidectomy (TOETVA): Complications, surgical time and learning curve.

10 mg100ul 50 UG2525200ug252525 mg252.5 mg

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#32619927   2020/06/30 To Up

Radiomic analysis identifies tumor subtypes associated with distinct molecular and microenvironmental factors in head and neck squamous cell carcinoma.

To identify whether radiomic features from pre-treatment computed tomography (CT) scans can predict molecular differences between head and neck squamous cell carcinoma (HNSCC) using The Cancer Imaging Archive (TCIA) and The Cancer Genome Atlas (TCGA).
Evangelia Katsoulakis, Yao Yu, Aditya P Apte, Jonathan E Leeman, Nora Katabi, Luc Morris, Joseph O Deasy, Timothy A Chan, Nancy Y Lee, Nadeem Riaz, Vaios Hatzoglou, Jung Hun Oh

1938 related Products with: Radiomic analysis identifies tumor subtypes associated with distinct molecular and microenvironmental factors in head and neck squamous cell carcinoma.



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#32619878   2020/06/24 To Up

Prolapsed cervical myoma during pregnancy.

Prolapsed submucosal myomas during pregnancy are uncommon, and few cases of patients undergoing vaginal myomectomy during pregnancy have been reported. In our center, a 13 weeks pregnant patient with prolapsed cervical myoma was diagnosed. Because of intermittent vaginal bleeding, surgery was scheduled at 13 weeks and 5 days of pregnancy. A vaginal myomectomy was performed. The postoperative course was uneventful. Cervical leiomyomas and prolapsed submucosal leiomyomas in pregnancy are rare clinical entities, and the literature is comprised of only case reports. We reviewed the current literature in regard to prolapsed cervical leiomyomas in pregnancy and provide an updated vision of the literature.
Virginia González González, Aránzazu Herráez Moreta, Alejandra Mayoral Triana, Luana Riolobos Sierra, Ignacio Cristóbal García, Nuria Izquierdo Méndez

1367 related Products with: Prolapsed cervical myoma during pregnancy.



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#32619713   2020/06/30 To Up

Three Photobiomodulation Protocols in the Prevention/Treatment of Radiotherapy-induced Oral Mucositis.

To compare three Photobiomodulation protocols to prevent/treat oral mucositis associated to radiotherapy.
Paulo André Gonçalves de Carvalho, Roberta Cardim Lessa, Dirce Maria Carraro, Antonio Cássio Assis Pellizzon, Graziella Chagas Jaguar, Fábio Abreu Alves

2598 related Products with: Three Photobiomodulation Protocols in the Prevention/Treatment of Radiotherapy-induced Oral Mucositis.

50 ul1 mg1 100ul5ug

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#32619584   2020/06/30 To Up

FOXN3 suppresses the growth and invasion of papillary thyroid cancer through the inactivation of Wnt/β-catenin pathway.

Forkhead box N3 (FOXN3) is a subtype of FOX family that has been demonstrated to be implicated in several cancers. However, the role of FOXN3 in papillary thyroid carcinoma (PTC) and its mechanisms have not yet been investigated. Our results showed that FOXN3 was markedly down regulated in PTC tissues and cell lines. Overexpression of FOXN3 suppressed the proliferation, colony formation, migration, and invasion in PTC cells. Overexpression of FOXN3 also prevented EMT process in PTC cells, as shown by the increased E-cadherin expression level and decreased expression levels of N-cadherin and vimentin. In addition, overexpression of FOXN3 inhibited tumor growth of PTC in vivo. Furthermore, overexpression of FOXN3 caused significant decreases in expression levels of β-catenin, c-Myc, and cyclin D1. Additionally, activation of Wnt/β-catenin pathway reversed the effects of FOXN3 on PTC cells. In conclusion, these findings indicated that FOXN3 exerted a tumor suppressive activity in PTC, which was mediated by Wnt/β-catenin pathway.
Chang'an Zhao, Liping Mo, Chao Li, Shuiping Han, Wenbo Zhao, Lifeng Liu

2207 related Products with: FOXN3 suppresses the growth and invasion of papillary thyroid cancer through the inactivation of Wnt/β-catenin pathway.

500 Units1Each1mg

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