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#32650350   2020/07/10 To Up

[Quality of Care for People with Home Mechanical Ventilation in Germany: A Scoping Review].

Outpatient intensive care for people with long-term mechanical ventilation is a rapidly growing area with a wide range of care demands. The aim of this Scoping Review is to present the current state of research on the quality of care for people with home mechanical ventilation in Germany and to identify research gaps.
Hanna Klingshirn, Laura Gerken, Peter Heuschmann, Kirsten Haas, Martha Schutzmeier, Lilly Brandstetter, Stephanie Stangl, Thomas Wurmb, Maximilian Kippnich, Bernd Reuschenbach

1769 related Products with: [Quality of Care for People with Home Mechanical Ventilation in Germany: A Scoping Review].

100 μg100ug100 μg100 μg100 μg100ug100 μg

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#32650342   2020/07/10 To Up

Protective Role of EGCG Against Malathion Induced Genotoxicity Using Human Lymphocytes.

Green tea (), which is the most common drink across the world after water, has many antioxidant properties. Epigallocatecin-3-gallate (EGCG) is a flavonoid which accounts for 33-50% of green tea solids. It functions as a powerful antioxidant, preventing oxidative damage in healthy cells, with antiangiogenic and antitumor activities and as a modulator of tumor cell response to chemotherapy. Malathion is an organophosphate pesticide which is widely used in agriculture, veterinary and industries. Oxidative stress has been identified as one of malathion's main molecular mechanisms. The purpose of this study was to evaluate protective role of EGCG against malathion induced genotoxicity using human lymphocyte model. Blood samples from 8 non-smoker healthy volunteers with no history of chemotherapy were collected and divided into six groups: Control, EGCG (50 µM), EGCG (20 µM), Malathion (24 µM), EGCG (50 µM)+Malathion (24 µM) and EGCG (20 µM)+Malathion (24 µM). For genotoxicity assay, we employed micronuclei test. For antioxidant capacity evaluation, GSH content and MDA levels were measured. Malathion showed significant genotoxic damage compared to the intact lymphocytes, however, treatment with EGCG at both concentrations were reduced the genotoxic effect of malathion. Malathion induced lipid peroxidation, while pre-treatment with EGCG at both concentrations, significantly protected the lymphocytes against malathion induced lipid peroxidation. Malathion significantly reduced GSH content, but pre-treatment with EGCG significantly recovered GSH content. Overall this study demonstrated that EGCG (at both concentrations) significantly prevents human lymphocytes against malathion induced genotoxicity and oxidative damage.
Seyed Mousa Taghavi, Amir Shadboorestan, Samin Sabzevari, Maryam Gholami, Razieh Keshavarz-Maleki, Hossein Mozdarani, Seyed Nasser Ostad, Omid Sabzevari

2608 related Products with: Protective Role of EGCG Against Malathion Induced Genotoxicity Using Human Lymphocytes.

100 ul 100 UG100 5 x 50 ug200 100 extractions50 ul 100ul1 mg200 5ug50 ug

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#32650341   2020/07/10 To Up

Defining EUS Features of Chronic Pancreatitis in Asians - A Multicentre Validation Study.

INTRODUCTION Although EUS features and criteria have been described in chronic pancreatitis, challenges remain with inter-operator variability and ease of adoption. AIMS The aim of the study was to define and validate EUS features of chronic pancreatitis in a multi-center prospective study in Asia. METHOD The study was conducted in 2 phases. In phase I, expert endosonographers across Asia reviewed standardized EUS videos of the pancreas for features diagnostic for chronic pancreatitis. Features that had good overall interobserver agreement were selected to derive EUS features for the diagnosis of chronic pancreatitis in Asians in a multi-centre case-control phase II study. Prospectively-enrolled cases had standard internationally validated radiologic or histologic features of chronic pancreatitis, and controls were patients without chronic pancreatitis who underwent EUS examination. RESULTS The top 6 EUS features that had good interobserver agreement (mean kappa = 0.73; range 0.60-0.90) were selected to be further evaluated in phase II study. These included: hyper-echoic foci with shadowing, lobularity with honeycombing, cysts, dilated ducts, dilated side branches, and calculi in main pancreatic duct. 284 subjects (132 cases, 152 controls) were enrolled from 12 centres in Asia. All 6 features had high accuracy ranging from 63.3% to 89.1%. 2 or more of these 6 EUS features accurately defined chronic pancreatitis (sensitivity 94.7% specificity 98.0%), with an AUROC of 0.986. CONCLUSION This is a multicentre Asian study that characterizes and defines the EUS features of chronic pancreatitis. This provides a useful tool in clinical practice and further research in pancreatic cancer surveillance.
Calvin Koh, Sundeep Lakhtakia, Mitsuhiro Kida, Cosmas Rinaldi Lesmana, Tiing Ang, Charles K F Vu, Than Aye Than, Sun Hwa Park, Majid Almadi, Charing Chong, Raymond Tang, Xi Wu, Hilmi Ida, Vinay Dhir, Nonthalee Pausawasdi, Basha Jahangeer, Zhendong Jin, Ai-Ming Yang, Anthony Teoh, Dong Wan Seo, Hsiu-Po Wang, Khek-Yu Ho

2179 related Products with: Defining EUS Features of Chronic Pancreatitis in Asians - A Multicentre Validation Study.

50 UG20 µl (10 mM)100 μg100 μg100ug100 μg

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#32650331   // To Up

Back-to-work Coronavirus infection control.


Jackie Dorst

1856 related Products with: Back-to-work Coronavirus infection control.

2 ml 1 mg 0.1 mg 1 mg100ug

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#32650320   2020/07/10 To Up

Amplitude versus spatially modulated electrotactile feedback for myoelectric control of two degrees of freedom.

Artificial proprioceptive feedback from a myoelectric prosthesis is an important aspect in enhancing embodiment and user satisfaction, possibly lowering the demand for visual attention while controlling a prosthesis in everyday tasks. Contemporary myoelectric prostheses are advanced mechatronic systems with multiple degrees of freedom, and therefore, to communicate the prosthesis state, the feedback interface needs to transmit several variables simultaneously. In the present study, two different configurations for conveying proprioceptive information of wrist rotation and hand aperture through multichannel electrotactile stimulation were developed and evaluated during online myoelectric control.
Martin Alexander Garenfeld, Christian Korfitz Mortensen, Matija Štrbac, Jakob L Dideriksen, Strahinja Dosen

1130 related Products with: Amplitude versus spatially modulated electrotactile feedback for myoelectric control of two degrees of freedom.

5 G 1 G100 Tests2.50 nmol 25 G100ug Lyophilized96 tests 0.1 mg

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#32650319   2020/07/10 To Up

A biomimetic electrical stimulation strategy to induce asynchronous stochastic neural activity.

Electrical stimulation is an effective method for artificially modulating the activity of the nervous system. However, current stimulation paradigms fail to reproduce the stochastic and asynchronous properties of natural neural activity. Here, we introduce a novel biomimetic stimulation (BioS) strategy that overcomes these limitations.
Emanuele Formento, Edoardo D'Anna, Sandra Gribi, Stephanie P Lacour, Silvestro Micera

2101 related Products with: A biomimetic electrical stimulation strategy to induce asynchronous stochastic neural activity.

1 kit1 kit200 ug100 assays3 modules100 assays 1 G100 assays100ug0.1 mg 96 Tests

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#32650315   2020/07/10 To Up

Single- versus dual-attending strategy for spinal deformity surgery: 2-year experience and systematic review of the literature.

Adult spinal deformity (ASD) surgery is complex and associated with high morbidity and complication rates. There is growing evidence in the literature for the beneficial effects of an approach to surgery in which two attending physicians rather than a single attending physician perform surgery for and oversee the surgical care of a single patient in a dual-attending care model. The authors developed a dual-attending care collaboration in August 2017 in which a neurosurgeon and an orthopedic surgeon mutually operated on patients with ASD.
Ivan Cheng, Martin N Stienen, Zachary A Medress, Kunal Varshneya, Allen L Ho, John K Ratliff, Anand Veeravagu

2984 related Products with: Single- versus dual-attending strategy for spinal deformity surgery: 2-year experience and systematic review of the literature.

200 units200 units 100ul1ml10 10 ug100ug200 ug0.1 mg200 mg

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#32650309   2020/07/10 To Up

Combined and simultaneous endoscopic endonasal and transorbital surgery for a Meckel's cave schwannoma: technical nuances of a mini-invasive, multiportal approach.

Over the years, Meckel's cave pathologies have been judged off-limits because of high rates of morbidity. Even though several studies have defined various surgical routes with tolerable morbidity and mortality rates, controversies related to the optimal avenue to treat different categories of Meckel's cave and cavernous sinus neoplasms persist.With unceasing energy to cultivate minimally invasive neurosurgical approaches, the endoscopic endonasal route has been tested, and the approach effectively performed, to provide a valid surgical window to these areas. In this dynamic and challenging scenario, another ventral endoscopic minimally invasive route-that is, the superior eyelid endoscopic transorbital approach-has been very recently proposed, and used in selected cases, to access the cavernous sinus and Meckel's cave regions.
Alberto Di Somma, Cristobal Langdon, Matteo de Notaris, Luis Reyes, Santiago Ortiz-Perez, Isam Alobid, Joaquim Enseñat

2146 related Products with: Combined and simultaneous endoscopic endonasal and transorbital surgery for a Meckel's cave schwannoma: technical nuances of a mini-invasive, multiportal approach.

100ug50 ug 100ug50 ug 50 ug 100ug96T100ug

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#32650304   2020/06/27 To Up

A temperature-controlled sample shuttle for field-cycling NMR.

We present a design for a temperature-controlled sample shuttle for use in NMR measurements at variable magnetic field strength. Accurate temperature control was achieved using a mixture of water-ethylene glycol as a heat transfer fluid, reducing temperature gradients across the sample to < 0.05 °C and minimising convection. Using the sample shuttle, we show how the longitudinal (T) and singlet order (T) relaxation time constants were measured for two molecules capable of supporting long-lived states, with new record lifetimes observed at low field and above ambient temperatures.
Andrew M R Hall, Topaz A A Cartlidge, Giuseppe Pileio

2132 related Products with: A temperature-controlled sample shuttle for field-cycling NMR.

1,000 tests96T16-22 Sample Kit8 Sample Kit16-22 Sample Kit100 assays8 Sample Kit16 Arrays/Slide96T96 samples

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