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Characterization of novel calcium hydroxide-mediated highly porous chitosan-calcium scaffolds for potential application in dentin tissue engineering.The aim of this study was to develop a highly porous calcium-containing chitosan scaffold suitable for dentin regeneration. A calcium hydroxide (Ca[OH] ) suspension was used to modulate the degree of porosity and chemical composition of chitosan scaffolds. The chitosan solution concentration and freezing protocol were adjusted to optimize the porous architecture using the phase-separation technique. Scanning electron microscopy/energy-dispersive spectroscopy demonstrated the fabrication of a highly porous calcium-linked chitosan scaffold (CH-Ca), with a well-organized and interconnected porous network. Scaffolds were cross-linked on glutaraldehyde (GA) vapor. Following a 28-day incubation in water, cross-linked CH scaffold had no changes on humid mass, and CH-Ca featured a controlled degradability profile since the significant humid mass loss was observed only after 21 (26.0%) and 28 days (42.2%). Fourier-transform infrared spectroscopy indicated the establishment of Schiff base on cross-linked scaffolds, along with calcium complexation for CH-Ca. Cross-linked CH-Ca scaffold featured a sustained Ca release up to 21 days in a humid environment. This porous and stable architecture allowed for human dental pulp cells (HDPCs) to spread throughout the scaffold, with cells exhibiting a widely stretched cytoplasm; whereas, the cells seeded onto CH scaffold were organized in clusters. HDPCs seeded onto CH-Ca featured significantly higher ALP activity, and gene expressions for ALP, Col1, DMP-1, and DSPP in comparison to CH, leading to a significant 3.5 times increase in calcium-rich matrix deposition. In sum, our findings suggest that CH-Ca scaffolds are attractive candidates for creating a highly porous and bioactive substrate for dentin tissue engineering.
2733 related Products with: Characterization of novel calcium hydroxide-mediated highly porous chitosan-calcium scaffolds for potential application in dentin tissue engineering.Breast invasive ductal ca calcium binding protein P Calcium hydroxide CAS Num Mouse Anti-Ca19.9 Sialyl Eosin 5 isothiocyanate, R Multiple lung carcinoma ( voltage-dependent calcium Screen Quest™ Luminomet Multiple organ cancer tes Breast invasive ductal ca Ovarian cancer tissue arr Cytokine (Human) Antibody
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Laparoscopic Transgastric Resection of a Gastrointestinal Stromal Tumor and Concomitant Sleeve Gastrectomy: a Case Report.Incidences of obesity, obesity surgeries, and gastric submucosal tumors (GST) have increased worldwide. This case report aims to demonstrate that concomitant laparoscopic transgastric resection (LTGR) of a gastrointestinal stromal tumor (GIST) near the esophagogastric junction (EGJ) can be performed safely and effectively in a patient with morbid obesity and scheduled sleeve gastrectomy (SG).
1578 related Products with: Laparoscopic Transgastric Resection of a Gastrointestinal Stromal Tumor and Concomitant Sleeve Gastrectomy: a Case Report.Gastrointestinal stromal Gastrointestinal stromal Multiple organ stromal tu Breast tumor tissue array Multiple organ gastrointe Brain tumor (meningioma, Adipose tissue disease sp Brain tumor and adjacent Brain tumor test tissue a Head and Neck tumor and n Testis tumor tissue array Spleen tumor test tissue
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ABA-dependent bZIP transcription factor, CsbZIP18, from Camellia sinensis negatively regulates freezing tolerance in Arabidopsis.Overexpression of the tea plant gene CsbZIP18 in Arabidopsis impaired freezing tolerance, and CsbZIP18 is a negative regulator of ABA signaling and cold stress. Basic region/leucine zipper (bZIP) transcription factors play important roles in the abscisic acid (ABA) signaling pathway and abiotic stress response in plants. However, few bZIP transcription factors have been functionally characterized in tea plants (Camellia sinensis). In this study, a bZIP transcription factor, CsbZIP18, was found to be strongly induced by natural cold acclimation, and the expression level of CsbZIP18 was lower in cold-resistant cultivars than in cold-susceptible cultivars. Compared with wild-type (WT) plants, Arabidopsis plants constitutively overexpressing CsbZIP18 exhibited decreased sensitivity to ABA, increased levels of relative electrolyte leakage (REL) and reduced values of maximal quantum efficiency of photosystem II (F/F) under freezing conditions. The expression of ABA homeostasis- and signal transduction-related genes and abiotic stress-inducible genes, such as RD22, RD26 and RAB18, was suppressed in overexpression lines under freezing conditions. However, there was no significant change in the expression of genes involved in the C-repeat binding factor (CBF)-mediated ABA-independent pathway between WT and CsbZIP18 overexpression plants. These results indicate that CsbZIP18 is a negative regulator of freezing tolerance via an ABA-dependent pathway.
2057 related Products with: ABA-dependent bZIP transcription factor, CsbZIP18, from Camellia sinensis negatively regulates freezing tolerance in Arabidopsis.Activating Transcription Rat monoclonal anti mouse Recombinant Human Intrins Rabbit Anti-Human Interfe Human Insulin-like Growth TGF beta induced factor 2 Rat monoclonal anti mouse Apoptosis Inducing Factor Recombinant Human WNT Inh Insulin promoter factor 1 Human, Allograft Inflamma Anti PDX1 Polyclonal Anti
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Effects of aging on foot pedal responses to visual stimuli.Car accidents due to unexpected forward or backward runaway by older drivers are a serious social problem. Although the cause of these accidents is often attributed to stepping on the accelerator instead of the brake, it is difficult to induce such pedal application errors systematically with usual drive simulators. We developed a simple personal computer system that induces the pedal errors, and investigate the effects of age on the error behaviors.
(S)-Amlodipine Di-p-Toluo Analysis Tool for AAH-TH1 Human normal fetal frozen ToughStripeâ„¢ BANDE Mouse Anti-C. botulinum T Native Influenza HA (A To 2 Tolylboronic acid CAS N Analysis Tool for AAM-CYT Total Mouse PAI-1 Antigen Rabbit Anti-Toxic Shock S Recombinant Toxoplasma go Rabbit Anti-Human Toll-Li
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Metformin Improves Quality of Post-Thaw Canine Semen.Sperm cryopreservation is an assisted reproductive technique routinely used in canine species for genetic conservation. However, during cryopreservation, the DNA damages are still elevated, limiting the fertilization rate. The present study was conducted to evaluate whether supplementation of canine semen extender with a molecule limiting the metabolic activities can improve the quality of frozen-thawed canine spermatozoa. We used metformin, known to limit the mitochondrial respiratory and limit the oxidative stress. Before and during the freezing procedure, metformin (50µM and 500µM) has been added to the extender. After thawing, sperm exposed to metformin conserved the same viability without alteration in the membrane integrity or acrosome reaction. Interestingly, 50µM metformin improved the sperm motility in comparison to the control, subsequently increasing mitochondrial activity and NAD content. In addition, the oxidative stress level was reduced in sperm treated with metformin improving the sperm quality as measured by a different molecular marker. In conclusion, we have shown that metformin is able to improve the quality of frozen-thawed dog semen when it is used during the cryopreservative procedure.
Interleukins Recombinant Goat Anti-Canine Heartwor Canine Haptoglobin ELISA Custom Canine IFN-gamma E Goat Anti-Heartworm (Cani Non-sterile canine serum Canine Complement Serum - Rapid Canine Brucella Ab Mouse anti Canine IgE ant Canine Complement Serum - Sheep Polyclonal Antibody Recombinant Canine ApoJ C
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Qualitative and quantitative comparison of Thiel and phenol-based soft-embalmed cadavers for surgery training.Surgical skills training has traditionally been limited to formalin embalming that does not provide a realistic model. The aim of this study was to qualitatively and quantitatively compare Thiel and phenol-based soft-embalming techniques: qualitatively in a surgical training setup, and quantitatively by comparing the mechanical and histomorphometric properties of skin specimens embalmed using each method.
1868 related Products with: Qualitative and quantitative comparison of Thiel and phenol-based soft-embalmed cadavers for surgery training.Androgen Receptor (Phosph Androgen Receptor , Mouse (5α,16β)-N-Acetyl-16-ac Androst-4-ene-3,17-dion-1 MarkerGeneTM Fluorescent Androstadienone C19H26O C Androstane-3a, 17b-diol 5 Androgen Receptor (Ab 650 ∆1-Androstene-3β,17β- Androstenedione 19 Androgen Receptor Ab-1 An Andrographolide C20H30O5
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[Occurrence and importance of colostral leukocytes].Leukocytes have been identified as a physiological component of colostrum in numerous animal species. In each of the examined species, they have been shown to occur in a typical amount exhibiting slight differences in the composition of leukocyte subpopulations. According to previous opinions, colostral leukocytes merely accidentally transfer from blood to milk or represent a sign of mastitis. In contrast to this, it is now considered to be current knowledge that special mechanisms exist enabling these leukocytes to actively transfer into colostrum. The presented review provides an overview of the recent literature and demonstrates the significance of colostral leucocytes. In analogy to the passage of maternal immunoglobulins, colostral leukocytes migration also leads to a transition of immunity. The cells are enterally absorbed and distributed throughout the neonatal organism. Colostral leukocytes are found to accumulate in certain tissues and organs without losing their immunologic function. Merely the leucocytes of the own mother are absorbed and these cells complement the newborns' immune system. As several studies have demonstrated, this is not solely due to the cells' mere immunological function but also a consequence of a regulatory effect on the neonatal immune system. Especially T-helper and further regulatory cell types transferred via colostrum may help the newborn in optimizing and maturing their immunological situation. Colostral treatment methods such as mixing, freezing, heating and acidifying modifications warrant re-evaluation taking the above aspects under consideration.
5α-Androstan-3β-ol � Androstane 3a, 17b diol 5 anti CD45 Leukocytes 19 Hydroxy 4 androstene 3 Androgen Receptor (Ab 650 Rabbit anti Androgen Rece Androgen Receptor Androgen Receptor 5α-N-Acetyl-2'H-androst- 3β-O-Acetyl-androsta-5,1 3-O-Acetyl-17-O-tert-buty CAR,Car,Constitutive andr