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#35045504   // To Up

[Mass Screening of Oral Cancer in Eastern Shimane Prefecture during 2015-2019].

The Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine, has been conducting mass screening of oral cancer using oral abrasion cytology by oral surgeons in eastern Shimane prefecture for public awareness and its early detection. As a result, 3(0.09%)cases of oral cancer were identified. Case 1: The patient was diagnosed with well-differentiated squamous cell carcinoma in the floor of the mouth(pT1N0M0, Stage Ⅰ)after undergoing Matsue city oral cancer screening in 2016. Case 2: The patient underwent oral cancer screening in Izumo city in 2018 and was diagnosed with verrucous carcinoma in the back of the tongue(pT1N0M0, Stage Ⅰ). Case 3: The patient was diagnosed with highly differentiated squamous cell carcinoma of the palate(pT1N0M0, Stage Ⅰ)after undergoing the Izumo city oral cancer screening in 2019. Awareness of oral cancer is important, and cancer screening by oral surgeons using cytology is highly useful and should be continued in the future.
Satoe Okuma, Yuhei Matsuda, Tomoko Ichiyama, Takashi Koike, Hiroto Tatsumi, Masaaki Karino, Tatsuo Okui, Yoshiki Nariai, Takahiro Kanno

2793 related Products with: [Mass Screening of Oral Cancer in Eastern Shimane Prefecture during 2015-2019].



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#35045494   // To Up

[A Case of Curative Resection for Borderline-Resectable Locally Advanced Rectal Cancer Treated with Preoperative Chemoradiotherapy followed by Extended Surgery].

A 55-year-old man was referred for surgery after colonoscopy revealed type 3 advanced lower rectal cancer in the lower rectum. CT and MRI scan showed no distant metastasis but on the left side of the rectum, there was a 34×30 mm large mass suspicious of lymph node metastasis, which had left-sided wall pelvic fascia invasion. We performed preoperative chemoradiotherapy(CRT)to ensure a secure surgical margin. As a result, the tumor volume was reduced and robot-assisted rectal amputation and bilateral lateral lymph node dissection were performed using a combined transperineal speculum approach. The pathological results showed that circumferential resection margin of 3 mm was secured. The lymph nodes on the left side of the rectum were mostly fibrotic and the tumor component had almost disappeared. Preoperative CRT is useful for securing the surgical margin. The multidisciplinary treatment including extended surgery enabled the curative resection of even highly advanced rectal cancer.
Tae Nakano, Jihyung Song, Naohito Beppu, Takaaki Matsubara, Yuya Takenaka, Kei Kimura, Akihito Babaya, Kozo Kataoka, Motoi Uchino, Hiroki Ikeuchi, Ikuo Matsuda, Seiichi Hirota, Masataka Ikeda

2824 related Products with: [A Case of Curative Resection for Borderline-Resectable Locally Advanced Rectal Cancer Treated with Preoperative Chemoradiotherapy followed by Extended Surgery].



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#35045479   // To Up

[A Case of Undifferentiated Carcinoma of Gallbladder with Five Year Recurrence-Free Survival after Radical Resection].

A woman in her 60s realized heart palpitations and was pointed out anemia. CT revealed a tumor measuring 7 cm, with internal necrosis, originating from the gallbladder and invading the liver, and diagnosed as gallbladder cancer. There existed no distant metastasis and we performed cholecystectomy with partial resection of segment 4a+5 of the liver and lymph node resection. Histopathological examination revealed highly atypical cells with large nuclei and polynuclear cells and poor cell junctions in the specimen, and the tumor was histologically diagnosed as an undifferentiated carcinoma. Metastases were not detected in dissected lymph nodes, and this case was diagnosed as undifferentiated carcinoma of gallbladder, T3a, N0, M0, Stage ⅢA(JSHBPS 6th). She was discharged at 13 days after the operation with no apparent postoperative complications. Postoperative adjuvant chemotherapy with administration of TS-1 was conducted for half a year. Now over 5 years have passed since the operation, and she is alive without recurrence.
Takefumi Itami, Hisateru Komatsu, Yujiro Nishizawa, Akira Inoue, Yoshinori Kagawa, Yasuhiro Miyazaki, Akira Tomokuni, Hiroaki Fushimi, Masaaki Motoori, Kazumasa Fujitani, Kazuhiro Iwase

1793 related Products with: [A Case of Undifferentiated Carcinoma of Gallbladder with Five Year Recurrence-Free Survival after Radical Resection].



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#35045433   // To Up

[Cooperative Surgery with Gastroenterological Surgeons in Gynecologic Malignant Tumors].

Secondary debulking surgery(SDF)for gynecologic malignancies may improve prognosis. However, recurrent lesions may be invasions of the intestinal tract and observed peritoneal dissemination. SDF can be safely carried out by performing cooperative surgery with a gastroenterological surgeon and gynecologists. Precise cooperation is indispensable for the operation, especially when it comes to aspects such as the contact method and perioperative management at that time. In our hospital, if the gynecologist suspects other organs invasion during a preoperative examination, they contact the gastroenterological surgeon in an elective manner. If other organs invasion is not clear during a preoperative examination or bowel injury occurs during surgery, the gastroenterological surgeon would be contacted urgently. To ensure smooth cooperation, it is necessary to run regular joint conferences. By sharing in planned and combining the expertise of all the department of interest, it is possible to perform highly curative and safe surgery.
Satoshi Arakawa, Yukio Asano, Hiroyuki Kato, Masahiro Shimura, Daisuke Koike, Chihiro Hayashi, Takayuki Ochi, Kenshiro Kamio, Toki Kawai, Hironobu Yasuoka, Takahiko Higashiguchi, Masahiro Ito, Fumi Utsumi, Kiyosumi Shibata, Akihiko Horiguchi

2495 related Products with: [Cooperative Surgery with Gastroenterological Surgeons in Gynecologic Malignant Tumors].



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#35045405   2022/01/19 To Up

Analysis of respiratory kinematics: a method to characterize breaths from motion signals.

Breathing motion (respiratory kinematics) can be characterized by the interval and depth of each breath, and by magnitude-synchrony relationships between locations. Such characteristics and their breath-by-breath variability might be useful indicators of respiratory health. To enable breath-by-breath characterization of respiratory kinematics, we developed a method to detect breaths using motion sensors. In 34 volunteers who underwent maximal exercise testing, we used 8 motion sensors to record upper rib, lower rib and abdominal kinematics at 3 exercise stages (rest, lactate threshold and exhaustion). We recorded volumetric air flow signals using clinical exercise laboratory equipment and synchronized them with kinematic signals. Using instantaneous phase landmarks from the analytic representation of kinematic and flow signals, we identified individual breaths and derived respiratory rate (RR) signals at 1Hz. To evaluate the fidelity of kinematics-derived RR, we calculated bias, limits of agreement, and cross-correlation coefficients (CCC) relative to flow-derived RR. To identify coupling between kinematics and flow, we calculated the Shannon entropy of the relative frequency with which flow landmarks were distributed over the phase of the kinematic cycle. We found good agreement in the kinematics-derived and flow-derived RR signals [bias (95% limit of agreement) = 0.1 (± 7) breaths/minute; CCC median (IQR) = 0.80 (0.48 - 0.91)]. In individual signals, kinematics and flow were well-coupled (entropy 0.9-1.4 across sensors), but the relationship varied within (by exercise stage) and between individuals. The final result was that the flow landmarks did not consistently localize to any particular phase of the kinematic signals (entropy 2.2-3.0 across sensors). The Analysis of Respiratory Kinematics method can yield highly resolved respiratory rate signals by separating individual breaths. This method will facilitate characterization of clinically significant breathing motion patterns on a breath-by-breath basis. The relationship between respiratory kinematics and flow is much more complex than expected, varying between and within individuals.
William Bonner Ashe, Sarah E Innis, Julia N Shanno, Camille J Hochheimer, Ronald Dean Williams, Sarah Jane Ratcliffe, J Randall Moorman, Shrirang Mukund Gadrey

1159 related Products with: Analysis of respiratory kinematics: a method to characterize breaths from motion signals.

1 module1 module1 module1 module1 module1 module1 module1 module1 module1 module1 module3 modules

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#35045386   2022/01/13 To Up

Preparation of high solid content oxidized starch by acid pretreatment-HO oxidation and its performance as the ligand in zirconium tanning.

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Jiaying Wang, Yue Yu, Wang Yue, Yuhe Feng, Ya-Nan Wang, Bi Shi

1954 related Products with: Preparation of high solid content oxidized starch by acid pretreatment-HO oxidation and its performance as the ligand in zirconium tanning.

0.1ml (1mg/ml)96 assays400Tests4 Membranes/Box 5 G1004 Arrays/Slide50 ug 100 UG

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#35045385   2022/01/16 To Up

Investigating the association between regeneration of urban blue spaces and risk of incident chronic health conditions stratified by neighbourhood deprivation: A population-based retrospective study, 2000-2018.

Chronic non-communicable diseases are leading causes of poor health and mortality worldwide, disproportionately affecting people in highly deprived areas. We undertook a population-based, retrospective study of 137,032 residents in Glasgow, Scotland, to investigate the association between proximity to urban blue spaces and incident chronic health conditions during a canal regeneration programme. Hazard ratios (HRs) were estimated using Cox proportional hazards models adjusted for age and sex, with the incidence of a given health condition as the dependent variable. The analyses were stratified by socioeconomic deprivation tertiles. We found that, in areas in the highest deprivation tertile, proximity to blue space was associated with a lower risk of incident cardiovascular disease (HR 0.85, 95% Confidence Interval (CI) 0.76-0.95), hypertension (HR 0.85, 95% CI 0.79-0.92), diabetes (HR 0.88, 95% CI 0.83-0.94), stroke (HR 0.85, 95% CI 0.77-0.94) and obesity (HR 0.90, 95% CI 0.86-0.94), but not chronic pulmonary disease, after adjusting for age and sex covariates. In middle and low deprivation tertiles, living closer to the canal was associated with a higher risk of incident chronic pulmonary disease (middle: HR 1.56, 95% CI 1.24-1.97, low: HR 1.34, 95% CI 1.05-1.73). Moreover, in the middle deprivation tertile, a higher risk of stroke (HR 1.36, 95% CI 1.02-1.81) and obesity (HR 1.14, 95% CI 1.01-1.29) was observed. We conclude that exposure to blue infrastructure could be leveraged to mitigate some of the health inequalities in cities.
Zoë Tieges, Michail Georgiou, Niamh Smith, Gordon Morison, Sebastien Chastin

1559 related Products with: Investigating the association between regeneration of urban blue spaces and risk of incident chronic health conditions stratified by neighbourhood deprivation: A population-based retrospective study, 2000-2018.

1 kit100ug200 Tests1,000 tests1 kit 25 G 500 ml One 96-Well Microplate Ki1 mg

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#35045371   2022/01/04 To Up

Metal-organic frameworks with peroxidase-like activity for efficient removal of aflatoxin B.

Aflatoxin B (AFB), a naturally produced toxin existing in major food crops, is highly toxic and carcinogenic to human and animals. In this study, a reusable material, [email protected] with great adsorption performance and peroxidase-like activity was synthesized for the removal of AFB. [email protected] exhibited great adsorption performance owing to hierarchical porous structure. [email protected] also could catalyze the AFB in the presence of HO due to the Fe-tetrakis (4-carboxyphenyl) porphyrin and Pd as effective peroxidase active site, which improved the removal efficiency of AFB. [email protected] was applied for the removal of AFB with a removal rate of 96.52% in 2 h. Owing to the advantages of high removal efficiency and reusability, [email protected] had great application potential in AFB removal.
Jinhui Wei, Xiangchuan Wu, Chengyuan Wu, Fan Hou, Lina Wu, He Huang

1150 related Products with: Metal-organic frameworks with peroxidase-like activity for efficient removal of aflatoxin B.

100ul100 assays100ul50 mL15 ml100μl100ug Lyophilized96 assays 1 G200 Tests

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#35045370   2022/01/11 To Up

Preparation of highly stable oleogel-based nanoemulsions for encapsulation and controlled release of curcumin.

Oleogels have been proposed as suitable systems for the encapsulation and delivery of lipophilic bioactive compounds. This work aimed to produce stable nanoemulsions of gelled-oil particles using monoglyceride (MG) oleogels loaded with curcumin. High-speed homogenization followed by ultrasonication was used for obtaining colloidal dispersions. The effects of ultrasonication processing parameters and formulation were evaluated to optimize particle size, polydispersity index (PDI), and stability during storage. All sonication parameters had a significant effect on particle size and PDI. A Pluronic F-68 + Tween 80 surfactant mixture with the lowest oleogel/aqueous phase ratio (5/95) produced nanoemulsions which were at least 10-month stable. The nanoemulsions showed a higher encapsulation efficiency than the sample without the gelator (73.85-91.05% vs. 56.99%). Furthermore, it was corroborated that structuring oil particles with MG crystals produces a matrix that entraps curcumin molecules and slows down their release. These findings provide useful information for the development of new nutraceutical products.
Camila A Palla, Aixa Aguilera-Garrido, María Elena Carrín, Francisco Galisteo-González, María José Gálvez-Ruiz

2119 related Products with: Preparation of highly stable oleogel-based nanoemulsions for encapsulation and controlled release of curcumin.

5 G1000 assays100 assays1000 assays100preparations100tests100 assays150 ug10000 assays

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