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CT features of thyroid nodules with isolated macrocalcifications detected by ultrasonography.A thyroid nodule with an isolated macrocalcification is visualized as a calcified nodule with complete posterior shadowing on ultrasonography (US). This study aimed to determine the computed tomography (CT) features of isolated macrocalcifications detected using US.
1361 related Products with: CT features of thyroid nodules with isolated macrocalcifications detected by ultrasonography.Rabbit Anti-CTNNBL1 Beta Rabbit Anti-TSSK6 CT72 Po Thyroid cancer metastasis Rabbit Anti-CTNNBL1 Beta Rabbit Anti-TSSK6 CT72 Po CtIP antibody Source Rabb Rabbit Anti-Human CTRP5 C CTBP1 Antibody Recombinant Human CTLA4 C Recombinant Human CTSL1 P Mouse AntiRNA polymerase CTMP
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Incomplete Hydrolysis of Curcumin Conjugates by β-Glucuronidase: Detection of Complex Conjugates in Plasma.The diphenol curcumin from turmeric is rapidly metabolized into phase II conjugates following oral administration, resulting in negligible plasma concentration of the free compound which is considered the bioactive form. Total plasma concentration of curcumin is often quantified after treatment with β-glucuronidase to hydrolyze curcumin-glucuronide, the most abundant conjugate in vivo. The efficiency of enzymatic hydrolysis has not been tested.
1772 related Products with: Incomplete Hydrolysis of Curcumin Conjugates by β-Glucuronidase: Detection of Complex Conjugates in Plasma.MarkerGene™ Biotin Dete Rabbit Plasma US Origin I Rabbit Plasma US Origin I Rabbit Plasma US Origin I Anti Avidin peroxidase co Plasma Proteins: Corn Try MarkerGeneTM in vivo lacZ Anti Bordetella pertussis Anti AGO2 Human, Monoclon Prolactin-Inducible Prote Rabbit Plasma US Origin I Bovine prolactin-induced
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The Putative Caloric Restriction Mimetic Resveratrol has Moderate Impact on Insulin Sensitivity, Body Composition and the Metabolome in Mice.Data on resveratrol-(trans-3,5,4'-trihydroxystilbene)-induced caloric-restriction-(CR)-mimicking effects in mice receiving a high-fat diet (HFD) are contradictory. We hypothesized that this could possibly stem from different bioactivities of resveratrol (RSV) microbial metabolites.
1046 related Products with: The Putative Caloric Restriction Mimetic Resveratrol has Moderate Impact on Insulin Sensitivity, Body Composition and the Metabolome in Mice.FDA Standard Frozen Tissu Multiple organ tumor tiss FDA Standard Frozen Tissu Thermal Shaker with cooli FDA Standard Frozen Tissu MultiGene Gradient therm FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu Rabbit Insulin,INS ELISA Mouse Anti-Insulin, penta ELISA Insulin (TMB) ,Rat
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The 400-m Front Crawl Test: Energetic and 3D Kinematical Analyses.
Malignant melanoma test t Breast cancer test tissue FDA Standard Frozen Tissu Mesothelioma test tissue MyGenie 32 Thermal Block MultiGene OptiMax Thermal Multiple organ cancer tes Troponin I test card, ser Kidney cancer test tissue Malaria pan antigen test, Tissue array of ovarian g FDA Standard Frozen Tissu
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Activation of D1 receptors affects human reactivity and flexibility to valued cues.Reward-predicting cues motivate goal-directed behavior, but in unstable environments humans must also be able to flexibly update cue-reward associations. While the capacity of reward cues to trigger motivation ('reactivity') as well as flexibility in cue-reward associations have been linked to the neurotransmitter dopamine in humans, the specific contribution of the dopamine D1 receptor family to these behaviors remained elusive. To fill this gap, we conducted a randomized, placebo-controlled, double-blind pharmacological study testing the impact of three different doses of a novel D1 agonist (relative to placebo) on reactivity to reward-predicting cues (Pavlovian-to-instrumental transfer) and flexibility of cue-outcome associations (reversal learning). We observed that the impact of the D1 agonist crucially depended on baseline working memory functioning, which has been identified as a proxy for baseline dopamine synthesis capacity. Specifically, increasing D1 receptor stimulation strengthened Pavlovian-to-instrumental transfer in individuals with high baseline working memory capacity. In contrast, higher doses of the D1 agonist improved reversal learning only in individuals with low baseline working memory functioning. Our findings suggest a crucial and baseline-dependent role of D1 receptor activation in controlling both cue reactivity and the flexibility of cue-reward associations.
2900 related Products with: Activation of D1 receptors affects human reactivity and flexibility to valued cues.Rabbit Anti-Hepcidin-25 P Rabbit Anti-Fascin Actin Rabbit Anti-RNF36 Polyclo Rabbit Anti-CIDE B Polycl Rabbit Anti-ABCB6 Polyclo Primary antibody 20S Pro Rabbit Anti-ERN2 Polyclon Rabbit Anti-RRAS Polyclon Primary antibody eIF2β Rabbit Anti-ATAD5 Polyclo Rabbit Anti-GPR78 Polyclo Rabbit Anti-HIPK3 Polyclo
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The Role of the AIMP1 Pathway in Diabetic Retinopathy: AIMP1-Targeted Intervention Study in Diabetic Retinopathy.We characterized the role of aminoacyl-tRNA synthetase-interacting multifunctional protein 1 (AIMP1) in retinal inflammation and apoptosis regulation, both in vivo and in vitro. In addition, we used clinical specimens to show the relationship between AIMP1 and the development of diabetic retinopathy (DR).
2459 related Products with: The Role of the AIMP1 Pathway in Diabetic Retinopathy: AIMP1-Targeted Intervention Study in Diabetic Retinopathy.FDA Standard Frozen Tissu FDA Standard Frozen Tissu Multiple organ tumor tiss Thermal Shaker with cooli FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu MultiGene Gradient therm Jak Stat II Phospho-Speci TGF-Beta Signaling Phosph DiscoveryPak™ Hedgehog
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Differences in the Natural Enamel Surface and Acquired Enamel Pellicle following Exposure to Citric or Hydrochloric Acid.The aim of this study was to investigate variations in the interaction between enamel, that is, the acquired enamel pellicle (AEP) and citric or hydrochloric acid.
1479 related Products with: Differences in the Natural Enamel Surface and Acquired Enamel Pellicle following Exposure to Citric or Hydrochloric Acid.FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu Oral squamous cell cancer FDA Standard Frozen Tissu FDA Standard Frozen Tissu Cell Meter™ Fluorimetri Multiple organ tumor tiss Thermal Shaker with cooli 2 Tolylboronic acid CAS N Multiple organ cancer fro
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Plasma Permeabilization of Human Excised Full-Thickness Skin by µs- and ns-pulsed DBD.Cold atmospheric plasma (CAP) is gaining increasing importance as a medical or cosmetic treatment for various indications. The technology is best suited to the treatment of surfaces such as the skin and is already used in wound care and, in exemplary case studies, the reduction of superficial tumors. Several plasma sources have been reported to affect the skin barrier function and potentially enable drug delivery across or into plasma-treated skin.
2297 related Products with: Plasma Permeabilization of Human Excised Full-Thickness Skin by µs- and ns-pulsed DBD.Native full length fibron Pooled Normal Human Plasm Human Renin Prorenin doub Pooled Normal Human Plasm Pooled Normal Human Plasm Antibodies, Rabbit: Anti Single Donor Human Parkin Rabbit Anti-Human Androge Plasma Proteins: Anti Hum Goat Anti-Human Androgen Prostate-Specific Antigen Single Donor Human Colon
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A Moan of Pleasure Should Be Breathy: The Effect of Voice Quality on the Meaning of Human Nonverbal Vocalizations.Prosodic features, such as intonation and voice intensity, have a well-documented role in communicating emotion, but less is known about the role of laryngeal voice quality in speech and particularly in nonverbal vocalizations such as laughs and moans. Potentially, however, variations in voice quality between tense and breathy may convey rich information about the speaker's physiological and affective state. In this study breathiness was manipulated in synthetic human nonverbal vocalizations by adjusting the relative strength of upper harmonics and aspiration noise. In experiment 1 (28 prototypes × 3 manipulations = 84 sounds), otherwise identical vocalizations with tense versus breathy voice quality were associated with higher arousal (general alertness), higher dominance, and lower valence (unpleasant states). Ratings on discrete emotions in experiment 2 (56 × 3 = 168 sounds) confirmed that breathiness was reliably associated with positive emotions, particularly in ambiguous vocalizations (gasps and moans). The spectral centroid did not fully account for the effect of manipulation, confirming that the perceived change in voice quality was more specific than a general shift in timbral brightness. Breathiness is thus involved in communicating emotion with nonverbal vocalizations, possibly due to changes in low-level auditory salience and perceived vocal effort.
2423 related Products with: A Moan of Pleasure Should Be Breathy: The Effect of Voice Quality on the Meaning of Human Nonverbal Vocalizations.TCP-1 theta antibody Sour Tissue array of ovarian g Mouse Anti-Human TNF-beta Beta Amyloid (1 42) High Rabbit Anti-Human TNF-bet Mouse Anti-beta-Amyloid(1 Mouse Anti-Human Guanylat Mouse Anti-Human hCG beta Mouse Anti-Human CD8-beta Mouse Anti-Human hCG (bet Rabbit Anti-Human PDGF R- Anti beta3-AR Human, Poly
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Effect of antioxidants on the HO-induced premature senescence of human fibroblasts.The study was aimed at evaluation of the role of secondary oxidative stress in the stress-induced premature senescence (SIPS) of human fibroblasts induced by HO. Two fibroblast lines were used: lung MRC-5 and ear H8F2p25LM fibroblasts. The lines differed considerably in sensitivity to HO (IC of 528 and 33.5 μM, respectively). The cells were exposed to HO concentrations corresponding to IC and after 24 h supplemented with a range of antioxidants. Most of antioxidants studied slightly augmented the survival of fibroblasts at single concentrations or in a narrow concentration range, but the results were not consistent among the cell lines. Chosen antioxidants (4-amino-TEMPO, curcumin, caffeic acid and -coumaric acid) did not restore the level of glutathione decreased by HO. Hydrogen peroxide treatment did not induce secondary production of HO and even decreased it, decreased mitochondrial potential in both cell lines and induced changes in the mitochondrial mass inconsistent between the lines. Antioxidant protected mitochondrial potential only in H8F2p25LM cells, but attenuated changes in mitochondrial mass. These results speak against the intermediacy of secondary oxidative stress in the SIPS induced by HO and suggest that the small protective action of antioxidants is due to their effects on mitochondria.
1128 related Products with: Effect of antioxidants on the HO-induced premature senescence of human fibroblasts.Recombinant Human PKC the Oncostatin M, human recom TGF beta induced factor 2 TCP-1 theta antibody Sour Mouse Anti-Human Fibrobla Recombinant Human PKC the Mouse anti human Oncostat Human Epstein-Barr Virus RFP Expressing Human Neon Anti AGO2 Human, Monoclon Oncostatin M, human recom Ofloxacin CAS Number [824
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