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#32769581   2020/08/06 To Up

Upper Airway Changes Following Different Orthognathic Surgeries, Evaluated by Cone Beam Computed Tomography: A Systematic Review and Meta-analysis.

This study sought to assess the upper airway changes following different orthognathic surgeries using cone-beam computed tomography.
Abbas Shokri, Kousar Ramezani, Arghavan Afshar, Jalal Poorolajal, Navid Ramezani

2652 related Products with: Upper Airway Changes Following Different Orthognathic Surgeries, Evaluated by Cone Beam Computed Tomography: A Systematic Review and Meta-analysis.

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#32767715   2020/08/07 To Up

Targeted skull base biopsies in the management of central skull base osteomyelitis.

Central skull base osteomyelitis has an infective pathology located in the deep-seated regions of the skull base, close to critical neurovascular structures. The disease has significant morbidity and mortality risks associated with it especially if early specific management is not initiated. The diagnostic and therapeutic challenges are in identifying the causative organisms and administering specific antimicrobial therapy on a long-term basis. The routine nasopharyngeal mucosal biopsies tend to be non-representative as the foci of infection is deep-seated and the infected bone sample is necessary to diagnose osteomyelitis. The targeted skull base biopsy technique described in this article outlines the principles of wide exposure and early identification of intraoperative landmarks in order to safely take biopsy and cultures from deep-seated regions, located close to the internal carotid artery.
Regi Thomas

1070 related Products with: Targeted skull base biopsies in the management of central skull base osteomyelitis.

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#32764969   2020/07/12 To Up

Giant Cell-Rich Solitary Fibrous Tumor in the Nasopharynx: Case Report and Literature Review.

Solitary fibrous tumors (SFTs) can occur in several locations outside the pleura, but rarely in the sinonasal tract, and particularly not in the nasopharynx. Herein, we describe an unusual case of giant cell-rich SFT (GCRSFT) occurring in the nasopharynx. A 64-year-old man experienced dizziness and headache for more than 10 years with no obvious cause. Computed tomography (CT) scan showed a 3.9 cm × 2 cm tumor on the posterior lateral wall of the left nasopharynx, and angiography revealed a hypervascular tumor fed by branches of the left carotid artery. Hence, preoperative embolization was performed, and then the tumor was endoscopically resected. The symptoms were relieved after the resection, and postoperative head CT and video laryngoscopy showed that the tumor was completely resected. We next characterized the specific pathological characteristics of the resected tumor. Histologically, the tumor was characterized by varying cellular proliferation of cytologically bland spindle cells within a collagenous stroma, with prominent interspersed branching vessels. Mitotic activity was low (2/50HPF), and there was no evidence of pleomorphism or tumor necrosis. Moreover, multinucleated giant cells with deep nuclear staining and distributed in pseudovascular spaces were found within the tumor. We ruled out the possibility that our case was giant cell fibroblastoma (GCF) by immunohistochemical analysis, showing that the tumor cells were positive for CD34, CD99, STAT6, and BCL-2, and that the Ki-67 labeling index was 3%, indicating that our case was SFT and not GCF. The patient's condition is generally good after a 14-month follow-up. This report serves to broaden the morphologic spectrum of GCRSFT and will help clinicians and pathologists better understand this entity to prevent misdiagnosis.
Shuang-Shuang Dong, Ning Wang, Cui-Ping Yang, Guo-Chang Zhang, Wei-Hua Liang, Jin Zhao, Yan Qi

1706 related Products with: Giant Cell-Rich Solitary Fibrous Tumor in the Nasopharynx: Case Report and Literature Review.



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#32759430   // To Up

Antibiotic resistance of the nasopharynx microbiota in patients with inflammatory processes.

The aim: To study the species composition of microorganisms isolated from patients with inflammatory processes of different localization and to monitor the sensitivity of isolated microorganisms to the most commonly used antibiotics.
Tetiana V Ivakhniuk, Viktoriia M Holubnycha, Vladyslav A Smiianov, Lesia A Rudenko, Yevgen V Smiianov

1101 related Products with: Antibiotic resistance of the nasopharynx microbiota in patients with inflammatory processes.

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#32757141   2020/08/05 To Up

Ectopic pituitary adenomas: clinical features, diagnostic challenges and management.

Ectopic pituitary adenomas (EPAs) are extremely rare pituitary adenomas located outside the sella turcica without any connection with intrasellar components. This study aims to review all the reported cases to date and describe the clinical characteristics of EPAs.
Jianyu Zhu, Zhicheng Wang, Yi Zhang, Xiaoxu Li, Jie Liu, Kan Deng, Lin Lu, Hui Pan, Renzhi Wang, Yong Yao, Huijuan Zhu

2357 related Products with: Ectopic pituitary adenomas: clinical features, diagnostic challenges and management.

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#32755442   2020/08/05 To Up

Nonkeratinizing Nasopharyngeal Carcinoma, Undifferentiated Type With Trisomy 2: A Case Report and Short Review of Cytogenetic and Molecular Literature.

Carcinoma originating from the surface epithelium of the nasopharynx is classified by the World Health Organization (WHO) as nasopharyngeal carcinoma (NPC) and has 3 main types: keratinizing squamous cell carcinoma (WHO type 1) and nonkeratinizing carcinoma, differentiated (WHO type II), and undifferentiated (WHO type III). Nonkeratinizing NPC is strongly associated with prior Epstein-Barr virus (EBV) infection. These tumors may be divided into differentiated and undifferentiated carcinoma. Histologically, the tumor is characterized by syncytia of large malignant cells with vesicular nuclei, conspicuous nucleoli, and easily observed mitotic figures. We report a case of a 14-year-old boy diagnosed with EBV and human papillomavirus (HPV)-positive NPC (WHO type 3) with cytogenetics showing the presence of mosaic trisomy 2. This case report brings to light a rare cytogenetic aberration to our knowledge only reported once before in the literature in a xenograft model.
Francesco Pontoriero, Ayaka M Silverman, Judy M Pascasio, Renu Bajaj

2020 related Products with: Nonkeratinizing Nasopharyngeal Carcinoma, Undifferentiated Type With Trisomy 2: A Case Report and Short Review of Cytogenetic and Molecular Literature.

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#32754222   2020/05/13 To Up

Respiratory Epithelial Adenomatoid Hamartoma: A Very Rare Entity Originating from the External Auditory Canal.

Respiratory epithelial adenomatoid hamartoma (REAH) is an uncommon lesion of the upper aerodigestive tract. It is characterized by abnormal glandular formations with ciliated epithelium arising from the nasal cavity, paranasal sinuses and nasopharynx, but other locations have also been described. We did not find any other cases of this hamartomas in the external auditory canal in the literature. A 40-year-old man was referred to the otorhinolaryngology department due to otorrhea and decreased hearing from 1 year ago. Otoscopic examination showed a reddish hemorrhagic mass in the left external auditory canal. Intraoperatively, the tumor was completely resected. The pathologic findings were consistent with REAH.
Behrouz Shokouhi, Parisa Mehrasa, Farzad Aslani

2575 related Products with: Respiratory Epithelial Adenomatoid Hamartoma: A Very Rare Entity Originating from the External Auditory Canal.

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#32750538   2020/08/01 To Up

Mass drug administration with azithromycin for trachoma elimination and the population structure of Streptococcus pneumoniae in the nasopharynx.

Mass drug administration (MDA) with azithromycin for trachoma elimination reduces nasopharyngeal carriage of Streptococcus pneumoniae in the short term. We evaluated S. pneumoniae carried in the nasopharynx before and after a round of azithromycin MDA to determine whether MDA was associated with changes in pneumococcal population structure and resistance.
Rebecca A Gladstone, Ebrima Bojang, John Hart, Emma M Harding-Esch, David Mabey, Ansumana Sillah, Robin L Bailey, Sarah E Burr, Anna Roca, Stephen D Bentley, Martin J Holland

1293 related Products with: Mass drug administration with azithromycin for trachoma elimination and the population structure of Streptococcus pneumoniae in the nasopharynx.

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#32749871   2020/08/04 To Up

The Utility of Gastrointestinal Endoscopic Examination Versus Positron Emission Tomography-Computed Tomography in the Detection of Second Primary Lesions in Korean Patients With Head and Neck Cancer.

Head and neck cancer often accompany a synchronous secondary primary lesion in the digestive tract. The aim of this study was to compare detection rates between positron emission tomography-computed tomography (PET-CT) and esophagogastroduodenoscopy (G-fiber) or colonoscopy (C-fiber) in the initial staging and to analyze risk factors for premalignant, malignant, and total synchronous secondary primary lesions.
Min-Su Kim, In Sik Song, Kyoung Ho Oh, Jae-Gu Cho, Seung-Kuk Baek, Jeong-Soo Woo, Kwang-Yoon Jung, Soon Young Kwon

1976 related Products with: The Utility of Gastrointestinal Endoscopic Examination Versus Positron Emission Tomography-Computed Tomography in the Detection of Second Primary Lesions in Korean Patients With Head and Neck Cancer.



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