Search results for: pathology
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Reducing the effect of DOAC interference in laboratory testing for factor VIII and factor IX: A comparative study using DOAC Stop and andexanet alfa to neutralize rivaroxaban effects.Investigation of factors (F) VIII and IX is common, with testing important for diagnosis or exclusion of haemophilia A or B, associated acquired conditions and factor inhibitors. Rivaroxaban, a common direct anti-Xa agent, causes significant interference in clotting assays, including substantial false reduction of factor levels.
1394 related Products with: Reducing the effect of DOAC interference in laboratory testing for factor VIII and factor IX: A comparative study using DOAC Stop and andexanet alfa to neutralize rivaroxaban effects.Rabbit Anti-factor VIII(F Apoptosis Inducing Factor Rabbit Anti-factor VIII(F Hamster anti mouse Insuli Growth Factor (Human) Ant Rabbit Anti-Human Interfe Factor VIII Related Anti Rabbit Anti-factor VIII(F Rabbit Anti-factor VIII(F Rabbit Anti-factor VIII(F Rabbit Anti-factor VIII(F Rabbit Anti-factor VIII(F
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Self-Reported Changes in Cognition, Communication and Swallowing in Multiple Sclerosis: Data from the Swedish Multiple Sclerosis Registry and from a National Survey.The aim of this study was to investigate self-reported cognition, speech, communication and swallowing changes in a large sample of individuals with multiple sclerosis (MS) in Sweden. A second aim was to update information about speech and language pathology (SLP) services received by people with MS (pwMS).
2384 related Products with: Self-Reported Changes in Cognition, Communication and Swallowing in Multiple Sclerosis: Data from the Swedish Multiple Sclerosis Registry and from a National Survey.Multiple organ tumor tiss Multiple head and neck ca Multiple organ cancer fro Multiple organ cancer and Multiple organ cancer tis Multiple tumor and normal Multiple head and neck ca High density (188 cases 2 Multiple ovarian cancer t Inflammation (Human) Quan Multiple organ tumor with Multiple organ cancer tes
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Distribution of Cardioembolic Stroke: A Cohort Study.A cardiac origin in ischemic stroke is more frequent than previously assumed, but it is not clear which patients benefit from cardiac work-up if obvious cardiac pathology is absent. We hypothesized that thromboembolic stroke with a cardiac source occurs more frequently in the posterior circulation compared with thromboembolic stroke of another etiology.
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Filum Terminale Ependymoma in an Infant with Meningocele.This report describes a case of an ependymoma found in the setting of tethered cord syndrome. We present a 3-month-old girl with prenatal diagnosis of lumbar meningocele who later underwent tethered cord release. After birth, she was neurologically intact and only found to have a skin-covered meningocele. An MRI was obtained and significant for low-lying conus terminating at L5, a focal syrinx, and Chiari II malformation. She underwent an elective meningocele repair and resection of thickened filum for tethered cord release at 3 months of age. Unexpectedly, microscopic evaluation of the filum was consistent with a small focus of ependymoma in addition to the filum tissue. Previous case reports have suggested a link between thickened filum in the setting of spinal dysraphism and myxopapillary ependymoma, but to our knowledge, this is the first report of ependymoma in the setting of tethered cord syndrome.
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Ultrafast Toluidine Blue Staining for Rapid On-Site Evaluation of Cytological Smears.Rapid on-site evaluation (ROSE) is one of cytopathology's "unique selling propositions." The quality, speed, and ease of handling of the staining used is a critical factor for the efficacy of the ROSE procedure. Here, we describe a modification of rapid toluidine blue staining that can be performed within 25 s, provides excellent nuclear morphology, and is compatible with subsequent Papanicolaou staining of the slides. Furthermore, exposure to hazardous chemicals is minimized, as no organic solvents other than the alcohol-based fixative and glycerin for temporary mounting and coverslipping are required. We have used this protocol successfully in our ROSE practice and have not observed any discrepancies between toluidine blue- and permanent Papanicolaou-stained slides.
2878 related Products with: Ultrafast Toluidine Blue Staining for Rapid On-Site Evaluation of Cytological Smears.Blue Feulgen DNA Ploidy Mouse Anti-Ca19.9 Sialyl Alcian Blue (pH 2.5) Sta Toluidine blue (C.I. 5204 Alcian Blue (pH 2.5) Sta REASTAIN® Quick Diff Kit Formamidinesulfinic acid UltraTek HRP Anti-Mouse Breast invasive ductal ca SYBR Green I Gel Staining CellQuanti-Blue™ Cell V CaspGLOW Red Active Caspa
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Intensified Histopathological Work-Up after Pancreatic Head Resection Reveals Relevant Prognostic Markers.Local recurrence remains a major problem after pancreatic head resection. Intensified histopathological work-up of surgical specimens after pancreatic head resection has revealed an increased number of incomplete resections (R1) depending on tumor infiltration front at the resection margins (RMs). It remains unclear to which extent the increased R1 resection rate has a clinical relevance for the patients' prognosis.
2637 related Products with: Intensified Histopathological Work-Up after Pancreatic Head Resection Reveals Relevant Prognostic Markers.Adar's Biotinilated Head and neck cancer tiss Head and neck squamous ca Mouse Anti-Lipoprotein Li Rabbit Anti-Trypsin (Panc PSA test card, serum , Ca High density pancreatic c Glucagon ELISA KIT, Rat G Pancreatic cancer and nor uPAR Blocking Peptide50 u Pancreatic cancer tissue Cardiac markers: Troponi
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Kikuchi-Fujimoto Disease-Like Inflammatory Reaction in a Silicone Breast Implant Seroma.Kikuchi-Fujimoto disease (KFD) may have an autoimmune etiology and some cases have been associated with silicone breast implants. Cytomorphologic features of the disease have been well characterized by fine-needle aspiration of lymph nodes. They are so specific as to permit a precise cytologic diagnosis. Cytologic features have not been reported in fluid specimens.
2993 related Products with: Kikuchi-Fujimoto Disease-Like Inflammatory Reaction in a Silicone Breast Implant Seroma.Breast disease spectrum t Breast disease spectrum t Breast disease spectrum t Breast invasive ductal ca Cervical carcinoma tissue Beta Amyloid (42) ELISA K Breast tumor survey tissu Breast fibroadenoma tissu Ovarian disease spectrum Breast disease spectrum ( Breast invasive ductal ca Breast tumor survey tissu
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Identification of key genes by integrating DNA methylation and next-generation transcriptome sequencing for esophageal squamous cell carcinoma.Aberrant DNA methylation leads to abnormal gene expression, making it a significant regulator in the progression of cancer and leading to the requirement for integration of gene expression with DNA methylation. Here, we identified 120 genes demonstrating an inverse correlation between DNA methylation and mRNA expression in esophageal squamous cell carcinoma (ESCC). Sixteen key genes, such as SIX4, CRABP2, and EHD3, were obtained by filtering 10 datasets and verified in paired ESCC samples by qRT-PCR. 5-Aza-dC as a DNA methyltransferase (DNMT) inhibitor could recover their expression and inhibit clonal growth of cancer cells in seven ESCC cell lines. Furthermore, 11 of the 16 genes were correlated with OS (overall survival) and DFS (disease-free survival) in 125 ESCC patients. ChIP-Seq data and WGBS data showed that DNA methylation and H3K27ac histone modification of these key genes displayed inverse trends, suggesting that there was collaboration between DNA methylation and histone modification in ESCC. Our findings illustrate that the integrated multi-omics data (transcriptome and epigenomics) can accurately obtain potential prognostic biomarkers, which may provide important insight for the effective treatment of cancers.
1010 related Products with: Identification of key genes by integrating DNA methylation and next-generation transcriptome sequencing for esophageal squamous cell carcinoma.Esophageal squamous cell Esophageal squamous cell Esophageal squamous cell Esophageal squamous cell Esophagus squamous cell c Esophagus squamous cell c Head and neck squamous ce Esophagus squamous cell c Lung squamous cell carcin Esophagus squamous cell c Skin squamous cell carcin Esophagus squamous cell c
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Acute hemoperitoneum after ruptured hepatocellular carcinoma: First Moroccan SCARE-compliant case report and literature review.Acute hemoperitoneum with a spontaneously ruptured hepatocellular carcinoma (HCC) is a rare type of internal bleeding that requires a multidisciplinary management approach.
2315 related Products with: Acute hemoperitoneum after ruptured hepatocellular carcinoma: First Moroccan SCARE-compliant case report and literature review.Liver hepatocellular carc Hepatocellular carcinoma Hepatocellular carcinoma Hepatocellular carcinoma Normal liver and hepatoce Hepatocellular carcinoma Hepatocellular carcinoma Hepatocellular carcinoma Liver cancer (hepatocellu Hepatocellular carcinoma Hepatocellular carcinoma Hepatocellular carcinoma
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Islet Macrophages Shift to a Reparative State following Pancreatic Beta-Cell Death and Are a Major Source of Islet Insulin-like Growth Factor-1.Macrophages play a dynamic role in tissue repair following injury. Here we found that following streptozotocin (STZ)-induced beta-cell death, mouse islet macrophages had increased Igf1 expression, decreased proinflammatory cytokine expression, and transcriptome changes consistent with macrophages undergoing efferocytosis and having an enhanced state of metabolism. Macrophages were the major, if not sole, contributors to islet insulin-like growth factor-1 (IGF-1) production. Adoptive transfer experiments showed that macrophages can maintain insulin secretion in vivo following beta-cell death with no effects on islet cell turnover. IGF-1 neutralization during STZ treatment decreased insulin secretion without affecting islet cell apoptosis or proliferation. Interestingly, high-fat diet (HFD) combined with STZ further skewed islet macrophages to a reparative state. Finally, islet macrophages from db/db mice also expressed decreased proinflammatory cytokines and increased Igf1 mRNA. These data have important implications for islet biology and pathology and show that islet macrophages preserve their reparative state following beta-cell death even during HFD feeding and severe hyperglycemia.
2372 related Products with: Islet Macrophages Shift to a Reparative State following Pancreatic Beta-Cell Death and Are a Major Source of Islet Insulin-like Growth Factor-1.IGF-1R Signaling Phospho- ELISA Human , 2 Screen Is Epidermal Growth Factor ( Rat monoclonal anti mouse thymic dendritic cell-der RABBIT ANTI HUMAN SDF-1 A Rat monoclonal anti mouse Epidermal Growth Factor ( Growth Differentiation Fa Rat monoclonal anti mouse Mouse Anti-Insulin-Like G Rat monoclonal anti mouse
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