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Electrical stimulation for treating pressure ulcers.Pressure ulcers (also known as pressure sores, decubitus ulcers or bedsores) are localised injuries to the skin or underlying tissue, or both. Pressure ulcers are a disabling consequence of immobility. Electrical stimulation (ES) is widely used for the treatment of pressure ulcers. However, it is not clear whether ES is effective.
Anti- ADAM-12 (A Disintig 2 Formyl imidazole (Imida QuantiChrom™ Formaldehy Benzyl (2S,3S,5S)-2-Hexyl Formalin (10% Neutral Bu Indole 6 carboxaldehyde ( Formamide Molecular biolo 2-Amino-6-formylpteridin- IDELISA™ Forensic Pento NATIVE HUMAN PROLACTIN, P Isopeptidase T (short for MOUSE ANTI HUMAN CD15, Pr
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Medical Emergencies During a Half Marathon Race - The Influence of Weather.
1906 related Products with: Medical Emergencies During a Half Marathon Race - The Influence of Weather.Normal rat multiple organ Thermal Shaker with cooli Rabbit anti PKC theta (Ab FDA Standard Frozen Tissu FDA Standard Frozen Tissu Sheep Anti-Theophylline 3 Multiple organ cancer tis TCP-1 theta antibody Sour Rabbit anti PKC theta (pS Tissue array of ovarian g FDA Standard Frozen Tissu Normal rat multiple organ
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Monte Carlo calculation of beam quality correction factors in proton beams using TOPAS/GEANT4.To provide Monte Carlo calculated beam quality correction factors () for monoenergetic proton beams using TOPAS, a toolkit based on the Monte Carlo code Geant4.
1567 related Products with: Monte Carlo calculation of beam quality correction factors in proton beams using TOPAS/GEANT4.Contact Factors: Human Fa Rabbit Anti-Cell death in BDNF & NTF4 Protein Prote Rabbit Anti-ING1 p33 Poly ELISA Mouse , Interleukin DiscoveryPak™ HDAC Inhi Goat Anti-Human EPB41L2 4 Ovary cancer tissue array Goat Anti- PGBD1, (intern Colon cancer test tissue JUP & CTNNA1 Protein Prot Mouse Inflammation Array
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Skyrmion flop transition and congregation of mutually orthogonal skyrmions in cubic helimagnets.Magnetic chiral skyrmions are particle-like excitations with a topological charge, which are currently considered as promising objects for the next generation of magnetic memory, logic, and neuromorphic devices. In three-dimensional systems, they can form rather complex topological structures. In bulk helimagnets, elongated skyrmion tubes can be ordered either perpendicularly or parallel to an external magnetic field and such configurations coexist in a specific range of fields. We have shown that with an increase in the magnetic field, the transition from perpendicular to parallel ordering in a 3D skyrmion dimer occurs through an intermediate state with mutually orthogonal skyrmion tubes. In the system with three and more skyrmion tubes, we uncovered a surprisingly large diversity of superstructures and systemized the principles of their formation. The nascent conical state is shown to induce the field-dependent switch between favored skyrmion clusters and underlies attracting inter-skyrmion potential. We argue that our numerical simulations on skyrmion clusters are valid in a parameter range corresponding to the A-phase region of cubic helimagnets. Moreover, skyrmionic superstructures constitute a novel concept of spintronic devices based on gapless skyrmion motion along with each other.
2759 related Products with: Skyrmion flop transition and congregation of mutually orthogonal skyrmions in cubic helimagnets.6-Chloro-3-indolyl-beta-D APC & CSNK2A1 Protein Pro Multiple stomach cancer t Rat monoclonal anti mouse Plasma Proteins: Corn Try Goat Anti- CITED2 (Intern Bladder cancer tissue arr Goat Anti- apolipoprotein Breast cancer test tissue CCNB1 & CDKN1A Protein Pr Mouse Anti-Plasmodium fal HSPB1 & DAXX Protein Prot
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EZH2 inhibitors restore epigenetically silenced CD58 expression in B-cell lymphomas.Loss of CD58 is a common mechanism for tumor immune evasion in lymphoid malignancies. CD58 loss is known to occur due to both genetic and non-genetic causes; therefore, we hypothesized that restoring CD58 expression in lymphoma cells may be an effective treatment approach. To explore the potential for restoring CD58 expression, we first screened 11 B-cell lymphoma lines and found that 3 had decreased CD58 expression. Among these, CD58 was genetically damaged in two lines but not in the third line. Using the cell line with downregulated CD58 without a genetic abnormality, we performed epigenetic library screening and found that two EZH2 inhibitors, EPZ6438 and GSK126, specifically enhanced CD58 expression. By examining the effect of three EZH2 inhibitors with different selectivity profiles in different B-cell lines, EZH2 inhibition was shown to have a common activity in upregulating CD58 expression. Restoring the expression of CD58 in lymphoma cells using an EZH2 inhibitor was shown to enhance interferon-γ production of T and NK cells against lymphoma cells. H3K27 was shown to be highly trimethylated in the CD58 promoter region, and EZH2 inhibition induced its demethylation and activated transcription of the CD58 gene. These results indicated that EZH2 is involved in the epigenetic silencing of CD58 in lymphoma cells as a mechanism for tumor immune escape, and EZH2 inhibitors are able to restore epigenetically suppressed CD58 expression. Our findings provide a molecular basis for the combination of an EZH2 inhibitor and immunotherapy for lymphoma treatment.
1302 related Products with: EZH2 inhibitors restore epigenetically silenced CD58 expression in B-cell lymphomas.DiscoveryPak™ Stem Cell Rabbit Anti-Cell death in DiscoveryPak™ EGFR Tyro DiscoveryPak™ Hedgehog Lung non small cell cance PLX-4032 Mechanisms: B-Ra Biocidal ZF, spray disinf Cell Cycle Phospho-Specif Jurkat Cell Extract (Indu CometAssay Electrophoresi CELLKINES Natural Human I Rabbit Anti-Cell death in
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Seasonal variation of atmospheric vertical extinction and its interaction with meteorological factors in the Yangtze River Delta region.Based on ground-based lidar and microwave radiometer observations in Hangzhou from 1 January 2013 to 31 December 2015, the monthly characteristics of diurnal extinction as well as atmospheric boundary layer (ABL) were studied. The interactions between temperature (T), humidity fields including relative humidity (RH) and specific humidity (SH) and atmospheric stratification (AS) were analyzed to discuss the meteorological factors in the Yangtze River Delta region during the study period. The top of ABL varied from 0.8 km to 1.0 km throughout in January with higher extinction intensity close to the surface combined to the largest PM about 100-120 μg/m. Then the ABL could develop up to 1.5 km in the spring due to the weaker extinction during the daytime. The RH in the whole column in January and December was lower than the mean value (ranging from 5% to 20%) distributed from the ground to 3 km. From May to September, the RH anomaly profiles became positive contributed to larger extinction by strengthened the particle scattering ability. In January and December, the AS was stable from the surface to 3 km coincided with the extinction distribution; while in July and August, the gradient of Δθ decreased which favored the diffusion of particle in the air. Moreover, April and October presented turning points in the variation of θ. The humidity field reveals a stable condition in January and December which favored particles suppressed from the near surface to 3 km; the temperature field has tended towards a neutral state in most months except for February. The first change-point of the meteorological fields was found in April possibly attributable to the abnormal abrupt in the subtropical high. This study could have important reference for understanding regional air quality and governing air control.
1000 related Products with: Seasonal variation of atmospheric vertical extinction and its interaction with meteorological factors in the Yangtze River Delta region.Goat Anti-Human Casein Ki Goat Anti-Human GALR2, (i MMP2 & A2M Protein Protei BID & RHOA Protein Protei Goat Anti-Human LRP5, (in CTNNA3 & CTNNB1 Protein P MAP3K3 & CHUK Protein Pro Goat Anti-Human PARK2, (i MYBL2 & RBL1 Protein Prot FGF5 & FGFR4 Protein Prot Goat Anti- SCN5A, (intern Syringe pump can be contr
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Nitrous oxide produced directly from ammonium, nitrate and nitrite during nitrification and denitrification.A hypothermia aerobic denitrifying bacterium, Pseudomonas taiwanensis strain J488, can effectively remove multiple nitrogen sources from wastewater at 15 °C. The ammonium, nitrate and nitrite removal efficiencies were 100 %, 92.61 % and 92.49 %, respectively. Strain J488 could survive with hydroxylamine as sole nitrogen source and its removal efficiency was 97.71 %. The removal efficiency of ammonium was 100 % even in the presence of the classical inhibitors of nitrification allylthiourea and diethyldithiocarbamate. These findings fundamentally changed the picture that the ammonia monooxygenase could be inhibited by the copper chelators of allylthiourea or diethyldithiocarbamate. Similarly, the nitrite removal capacity of strain J488 was not sensitive to inhibition by Pb, and its removal efficiency was also 100 %. Additionally, by identifying the intermediates accumulation of nitrification and denitrification, using nitrification and denitrification inhibitors, measuring enzyme activities and determining NO concentrations, it was demonstrated that NO could be produced directly from ammonium, nitrate and nitrite.
1816 related Products with: Nitrous oxide produced directly from ammonium, nitrate and nitrite during nitrification and denitrification.Anti Androgen Receptor pr Anti-Androgen Receptor pr Androgen Receptor Antibod 5α-N-Acetyl-2'H-androst- Androsta-1,4,6-triene-3,1 Epiandrosterone (3 beta H Androstane-3a,17b-diol Gl 4 Androstene 3,17 dione C Rabbit Anti-Human Androge Androgen Receptor (Phosph Androgen Receptor Antibod Ammonium nitrate CAS Numb
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Can You Get There from Here? An Analysis of Walkability Among pulsepoint CPR Alert Dispatches.Bystander CPR before the arrival of EMS is a major factor in out of hospital cardiac arrest (OHCA) survival. To recruit trained bystanders, mobile phone-based alert systems have been developed, but their limitations are not well understood.
2306 related Products with: Can You Get There from Here? An Analysis of Walkability Among pulsepoint CPR Alert Dispatches.Analysis Tool for AAH-CYT Mouse Anti-Canine Distemp Breast cancer tissue arra Uterus cancer tissue arra Frozen multiple human org Analysis Tool for AAH-INF Mouse Anti-Canine CD8 alp Pancreas cancer tissue ar Endometrium cancer tissue Cancer Antigen 50 (CA 50) Analysis Tool for AAM-ANG Rat Anti-Canine CD45, Bio
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A cryo-tomography-based volumetric model of the actin core of mouse vestibular hair cell stereocilia lacking plastin 1.Electron cryo-tomography allows for high-resolution imaging of stereocilia in their native state. Because their actin filaments have a higher degree of order, we imaged stereocilia from mice lacking the actin crosslinker plastin 1 (PLS1). We found that while stereocilia actin filaments run 13nm apart in parallel for long distances, there were gaps of significant size that were stochastically distributed throughout the actin core. Actin crosslinkers were distributed through the stereocilium, but did not occupy all possible binding sites. At stereocilia tips, protein density extended beyond actin filaments, especially on the side of the tip where a tip link is expected to anchor. Along the shaft, repeating density was observed that corresponds to actin-to-membrane connectors. In the taper region, most actin filaments terminated near the plasma membrane. The remaining filaments twisted together to make a tighter bundle than was present in the shaft region; the spacing between them decreased from 13 nm to 9 nm, and the apparent filament diameter decreased from 6.4 to 4.8 nm. Our models illustrate detailed features of distinct structural domains that are present within the stereocilium.
2696 related Products with: A cryo-tomography-based volumetric model of the actin core of mouse vestibular hair cell stereocilia lacking plastin 1.Normal mouse multiple org Tissue array of ovarian g Esophageal squamous cell Kidney clear cell carcino Mouse multiple organ norm Esophageal squamous cell Oral squamous cell cancer Non-small cell lung cance Normal rat multiple organ FDA Standard Frozen Tissu Normal rat multiple organ Diffuse large-B cell lymp
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Preparedness and proactive infection control measures against the emerging Wuhan coronavirus pneumonia in China.
1464 related Products with: Preparedness and proactive infection control measures against the emerging Wuhan coronavirus pneumonia in China.Colon cancer tissue array Breast cancer test tissue Cell Cycle Control Phosph Ovary cancer test tissue Pancreatic cancer test ti Brain tumor tissue array Liver cancer tissue array Testis tumor tissue array FDA Standard Frozen Tissu Stomach cancer test tissu Lung cancer test tissue a Mesothelioma test tissue
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