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#32649431   2020/07/06 To Up

Depth-dependent analysis of corneal cross-linking performed over or under the LASIK flap by Brillouin microscopy.

To determine the impact of corneal cross-linking (CXL) performed over the laser in situ keratomileusis (LASIK) flap (Standard CXL) or under the flap after flap lift (Flap-CXL) on regional corneal stiffness using Brillouin microscopy.
Hongyuan Zhang, Mehdi Roozbahani, Andre L Piccinini, Farhad Hafezi, Giuliano Scarcelli, J Bradley Randleman

2704 related Products with: Depth-dependent analysis of corneal cross-linking performed over or under the LASIK flap by Brillouin microscopy.

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#32649295   2020/07/10 To Up

Efficacy and safety of denosumab treatment in a prepubertal patient with cherubism.

Background Denosumab is an inhibitor of receptor activator of nuclear factor kappa-B ligand, which strongly suppresses osteoclasts. Cherubism is a rare autosomal dominant disorder characterized by symmetrical swelling of the jaws, in which the bone is replaced by a fibrous granuloma containing osteoclast-like giant cells. Case presentation We report the efficacy and safety of denosumab treatment in a prepubertal boy with progressive cherubism. The treatment consisting of eight subcutaneous denosumab injections (120 mg/dose) in 6 months not only suppressed the expansion of the osteolytic lesions but also dramatically ossified them. However, a transiently decreased growth rate and rebounded asymptomatic hypercalcemia were associated with the treatment. Conclusions The present case demonstrated the therapeutic potential of denosumab for treatment of cherubism, although adverse effects, especially those on childhood growth, remain obscure. Further studies are needed to establish a safe and effective protocol for denosumab treatment of children.
Haruka Kawamura, Satoshi Watanabe, Takashi I, Izumi Asahina, Hiroyuki Moriuchi, Sumito Dateki

1581 related Products with: Efficacy and safety of denosumab treatment in a prepubertal patient with cherubism.

100ug1 Set100.00 ug1 Set100 μg100 μg50100 μg

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#32648661   2020/07/10 To Up

GoDental! Enhancing flipped classroom experience with game-based learning.

To investigate the use of game-based learning (GBL) to enhance students' experience of the flipped classroom (FC) in dental education.
Melania Borit, Lina Stangvaltaite-Mouhat

2988 related Products with: GoDental! Enhancing flipped classroom experience with game-based learning.

100ug LyophilizedTwo 96-Well Microplate Ki 500 ml 100ug LyophilizedOne 96-Well Microplate Ki 100ul100ug Lyophilized50.00 ml100tests100ug LyophilizedOne 96-Well Microplate Ki

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#32648231   2020/07/09 To Up

Large surgically resected leiomyosarcoma of the liver: a case report.

Primary hepatic leiomyosarcoma (PHL) is an extremely rare type of tumor. We herein report a case of a large surgically resected leiomyosarcoma of the liver.
Takashi Maeda, Kyohei Yugawa, Nao Kinjo, Daisuke Imai, Kensaku Sanefuji, Koto Kawata, Shinichiro Ikeda, Keitaro Edahiro, Kazuki Takeishi, Tomohiro Iguchi, Noboru Harada, Mizuki Ninomiya, Shohei Yamaguchi, Kozo Konishi, Shinichi Tsutsui, Hiroyuki Matsuda

1300 related Products with: Large surgically resected leiomyosarcoma of the liver: a case report.



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#32646818   2020/07/06 To Up

One-month-old boy with group B streptococcal meningitis, subdural effusion, and high levels of interleukin-6.

Meningitis is associated with elevated levels of inflammatory cytokines in the blood, cerebrospinal fluid (CSF), and subdural fluid. Subdural effusion prolongs fever in patients with meningitis. However, the reason for this remains unclear. A healthy one-month-old boy was admitted after presenting with bacterial meningitis. He was administered meropenem, cefotaxime, and dexamethasone intravenously. On the 3rd day, blood and CSF cultures revealed the presence of Group B Streptococcus from samples collected on day 1. Subsequently, ampicillin and gentamicin replaced the previous combination of antimicrobials used. On the 4th day, brain magnetic resonance imaging with contrast showed bilateral cerebral ventriculitis and left subdural effusion. On the 11th day, since the subdural effusion had worsened, we performed a subdural puncture from the anterior fontanelle. Owing to the prolonged fever, he was intravenously injected immunoglobulin on day 13. He was afebrile on day 23. Antimicrobials were administered for 28 days. Levels of interleukin-6 (IL-6) in the serum and CSF were the highest on the 1st day at 20,600 pg/mL and 170,000 pg/mL, respectively, and decreased upon treatment. IL-6 concentration in the subdural fluid (30,000 pg/mL) was much higher than that in the serum (9 pg/mL) and CSF (2600 pg/mL). To the best of our knowledge, this is the first report on the cytokines in subdural fluid in patients with group B Streptococcal meningitis. Subdural effusion maintained high levels of IL-6 even after the levels in the blood and CSF decreased dramatically. This could explain why subdural effusion prolongs fever in patients with meningitis.
Akari Terada, Takuma Ohnishi, Yoshinori Mishima, Nao Akiyama, Yukiko Kanna, Shinya Asato, Mizue Tomita, Masako Ikemiyagi, Nobuaki Shikoro, Maki Nakazawa, Nobuyoshi Kurihara, Masahiro Tado, Akihiro Yachie, Isamu Kamimaki

1411 related Products with: One-month-old boy with group B streptococcal meningitis, subdural effusion, and high levels of interleukin-6.

96 Tests/kit 1000 ml 10 1 mg0.2 mg 5 G10, 10ml whole blood

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#32646203   2020/07/09 To Up

Comparison between Craniospinal Irradiation and Limited-Field Radiation in Patients with Non-metastatic Bifocal Germinoma.

Whether craniospinal irradiation (CSI) could be replaced by limited-field radiation in non-metastatic bifocal germinoma remains controversial. We addressed the issue based on the data from our series and the literature.
Bo Li, Wenyi Lv, Chunde Li, Jiongxian Yang, Jiajia Chen, Jin Feng, Li Chen, Zhenyu Ma, Youqi Li, Jiayi Wang, Yanwei Liu, Yanong Li, Shuai Liu, Shiqi Luo, Xiaoguang Qiu

1094 related Products with: Comparison between Craniospinal Irradiation and Limited-Field Radiation in Patients with Non-metastatic Bifocal Germinoma.

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