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Oxytocin receptor signaling modulates novelty recognition but not social preference in zebrafish.Sociality is a complex phenomenon that involves the individual's motivation to approach their conspecifics, along with social cognitive functions that enable individuals to interact and survive. The nonapeptide oxytocin (OXT) is known to regulate sociality in many species. However, the role of OXT in specific aspects of sociality is still not well understood. In the present study we investigated the contribution of the OXT receptor (OXTR) signaling in two different aspects of zebrafish social behavior: social preference, by measuring their motivation to approach a shoal of conspecifics, and social recognition, by measuring their ability to discriminate between a novel and familiar fish, using a mutant zebrafish lacking a functional OXTR. Although oxtr mutant zebrafish displayed normal attraction to a shoal of conspecifics, they exhibited reduced social recognition. We further investigated if this effect would be social-domain specific by replacing conspecific fish by objects. Although no differences were observed in object approach, oxtr mutant fish also exhibited impaired object recognition. Our findings suggest that OXTR signaling regulates a more general memory recognition of familiar vs. novel entities, not only in social but also in a non-social domain, in zebrafish.
2905 related Products with: Oxytocin receptor signaling modulates novelty recognition but not social preference in zebrafish.IGF-1R Signaling Phospho- Goat Anti- Notch1b (zebra Goat Anti- Notch1a (zebra T-Cell Receptor Signaling Rabbit Anti-Insulin Recep Goat Anti- Glucogon recep ELISA Human , Interleukin Rabbit Anti-Insulin Recep Goat Anti-Human Neuropept Goat Anti- Six3b (zebrafi ERK Signaling Phospho-Spe Goat Anti- Neurogenin 1 (
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Layer-by-layer printing of photopolymers in 3D: How weak is the interface?Additive manufacturing, or as also called, 3D-printing is considered as a game changer in replacing traditional processing methods in numerous applications, yet it has one intrinsic potential weakness related to bonding of layers formed during the printing process. Prior to finding solutions for improvement, a thorough quantitative understanding of the mechanical properties of the interface is needed. Here a quantitative analysis of the nano-mechanical properties in 3D printed photopolymers formed by digital light processing (DLP) stereolithography (SLA) is shown. Mapping of the contact Young's modulus across the layered structure is performed by Atomic Force Microscopy (AFM) with sub-micrometer resolution. PeakForce Quantitative Nanomechanical Mapping (PF-QNM) mode was employed in the AFM experiments. The layered specimens were obtained from an acrylate-based resin (PR48, Autodesk), containing also a light absorbing dye. We observed local depressions with values up to 30 % of the maximum stiffness at the interface between the consecutively deposited layers, indicating local depletion of molecular cross-link density. The thickness values of the interfacial layers were approximately 11 µm, which corresponds to ~ 22% of the total layer thickness (50 µm). We attribute this to heterogeneities of the photopolymerization reaction, related to (1) atmospheric oxygen inhibition, and (2) molecular diffusion across the interface. Additionally, a pronounced stiffness decay was observed across each individual layer with a skewed profile. This behaviour was rationalized by a spatial variation of the polymer cross-link density related to the variations of light absorption within the layers. This is caused by the presence of light absorbers in the printed material, resulting in a spatial decay of light intensity during photopolymerization.
1677 related Products with: Layer-by-layer printing of photopolymers in 3D: How weak is the interface?Rabbit Anti-Cell death in Rabbit Anti-Integrin alph Rabbit Anti-Cell death in Rabbit Anti-TNIP2 ABIN2 T Rabbit Anti-Insulin Recep Mouse Anti P.aeruginosa s Rabbit Anti-Integrin β2 Rabbit Anti-intestinal FA Rabbit Anti-TNIP2 ABIN2 T Rabbit Anti-Insulin Polyc Eosin 5 isothiocyanate, R Goat Anti-Human MDM2 (iso
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[Sepsis and Early Warning Score Systems].Sepsis is a significant cause of morbidity and mortality worldwide. Early diagnosis and management of sepsis is critical to improving patient prognoses. Surviving sepsis campaign guidelines issued in 2016 encourage health institutions to establish a screening system to identify patients who are at risk of sepsis. In 2012, the Royal College of Physicians in the UK began to advocate replacing local and regional scoring systems with the National Early Warning Score (NEWS), which is optimized for the identification of sepsis. Although many hospitals continue to use other scoring systems, all healthcare organizations are being encouraged to adopt a standardized scoring system to better promote patient safety by facilitating rapid diagnoses and screenings and thus, subsequently, improving decision-making by clinical staffs. NEWS plays a very important role in the treatment of sepsis patients. Although research findings related to this scoring system differ somewhat, they provide an important reference for clinical nursing staffs. Intelligent systems are not comprehensive in terms of their capabilities. However, combining human intelligence with system features and further optimizing the system should contribute significantly to the reduction of mortality risk in patients with sepsis.
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Evaluation of the presence of microorganisms from root canal of teeth submitted to retreatment due to prosthetic reasons and without evidence of apical periodontitis.The objective of this study was to evaluate the presence of microorganisms in the root canals (RC) of teeth submitted to endodontic retreatment due to prosthetic reasons and without evidence of apical periodontitis.
2656 related Products with: Evaluation of the presence of microorganisms from root canal of teeth submitted to retreatment due to prosthetic reasons and without evidence of apical periodontitis.Ofloxacin CAS Number [824 FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu FDA Standard Frozen Tissu EpiQuik Total Histone E Mouse Anti-Clostridium di 3 Trifluoromethylbenzonit Analysis Tool for AAH-INF Human Phospho-EGFR (Y992) Sheep Anti-S. aureus Exfo 1,5-Anhydro-4,6-O-benzyli
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Red and Processed Meats and Health Risks: How Strong Is the Evidence?Prevailing dietary guidelines have widely recommended diets relatively low in red and processed meats and high in minimally processed plant foods for the prevention of chronic diseases. However, an ad hoc research group called the Nutritional Recommendations (NutriRECS) consortium recently issued "new dietary guidelines" encouraging individuals to continue their current meat consumption habits due to "low certainty" of the evidence, difficulty of altering meat eaters' habits and preferences, and the lack of need to consider environmental impacts of red meat consumption. These recommendations are not justified, in large part because of the flawed methodologies used to review and grade nutritional evidence. The evidence evaluation was largely based on the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) criteria, which are primarily designed to grade the strength of evidence for clinical interventions especially pharmacotherapy. However, the infeasibility for conducting large, long-term randomized clinical trials on most dietary, lifestyle, and environmental exposures makes the criteria inappropriate in these areas. A separate research group proposed a modified and validated system for rating the meta-evidence on nutritional studies (NutriGRADE) to address several limitations of the GRADE criteria. Applying NutriGRADE, the evidence on the positive association between red and processed meats and type 2 diabetes was rated to be of "high quality," while the evidence on the association between red and processed meats and mortality was rated to be of "moderate quality." Another important limitation is that inadequate attention was paid to what might be replacing red meat, be it plant-based proteins, refined carbohydrates, or other foods. In summary, the red/processed meat recommendations by NutriRECS suffer from important methodological limitations and involve misinterpretations of nutritional evidence. To improve human and planetary health, dietary guidelines should continue to emphasize dietary patterns low in red and processed meats and high in minimally processed plant foods such as fruits and vegetables, whole grains, nuts, and legumes.
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Sedentary behaviour is associated with depression symptoms: Compositional data analysis from a representative sample of 3233 US adults and older adults assessed with accelerometers.Evidence supporting the individual associations of sedentary behaviours with depression symptoms commonly ignores the inherent co-dependency between physical activity, sedentary behaviours and sleep in a given 24-hour period. Data analysis based on compositional methods effectively deals with this issue.
1787 related Products with: Sedentary behaviour is associated with depression symptoms: Compositional data analysis from a representative sample of 3233 US adults and older adults assessed with accelerometers.Rabbit Anti-USP3 Polyclon Rabbit Anti-USP10 Polyclo Rabbit Anti-USP10 Polyclo Bovine Androstenedione,AS Rabbit Anti-USP3 Polyclon Rabbit Anti-USP10 Polyclo Rabbit Anti-USP3 Polyclon Rabbit Anti-USP3 Polyclon Rabbit Anti-USP10 Polyclo Rabbit Anti-USP10 Polyclo Rabbit Anti-USP3 Polyclon Rapid Mouse Ig Isotyping
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Clinical and radiographic evaluations of implant-supported cantilever fixed partial dentures replacing maxillary anterior teeth: A randomized clinical trial.Replacing maxillary or mandibular anterior teeth with implant-supported prostheses is challenging because of the small mesiodistal and buccolingual dimensions, which can affect the number and position of implants and thus the definitive prosthetic design.
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Influence of the Anion on the Oxidation of 5-Hydroxymethylfurfural by Using Ionic-Polymer-Supported Platinum Nanoparticle Catalysts.Platinum nanoparticles stabilized by an imidazolium-based cross-linked polymer (with chloride as the counteranion) efficiently catalyzed the oxidation of 5-hydroxymethylfurfural to form 2,5-furandicarboxylic acid in water under mild conditions with oxygen as the oxidant. This catalyst system is explored herein by varying the counteranion, that is, replacing chloride by BF , PF , bis(trifluoromethylsulfonyl)imide, hexanoate, or laurate anions, in the cationic polymer. The counteranion influences the structure of the obtained platinum nanoparticles, the surface electronic properties, and their catalytic activity. The highest reaction rates were obtained with the weakly nucleophilic bis(trifluoromethylsulfonyl)imide anion, which also favored platinum in the zero oxidation state, leading to complete conversion of the substrate and a high yield of 2,5-furandicarboxylic acid under mild conditions.
2652 related Products with: Influence of the Anion on the Oxidation of 5-Hydroxymethylfurfural by Using Ionic-Polymer-Supported Platinum Nanoparticle Catalysts.Sheep Anti-Theophylline 3 FDA Standard Frozen Tissu MyGenie 32 Thermal Block Recombinant Thermostable TCP-1 theta antibody Sour Rabbit anti PKC theta (pS Tissue array of ovarian g FDA Standard Frozen Tissu Multiple organ cancer tis CSL Gradient Thermal Cycl Pfu DNA Polymerase protei Ofloxacin CAS Number [824
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The detection sensitivity of commonly used singlet oxygen probes in aqueous environments.The sensitivity for singlet oxygen (O) of two convenient O probes, 1,3-diphenylisobenzofuran (DPBF) and 9,10-Anthracenediyl-bis(methylene)dimalonic acid (ABDA), has been investigated in different aqueous environments. Both probes are commercially available at reasonable cost and can be used with standard UV-vis spectrometers. Although DPBF is not soluble in neat water and is not specific to the detection of O, it has very high, essentially diffusion-limited, reactivity towards O; it can trap up to 50% of all O created in alcohol/water or micellar solution, and even more when replacing HO by DO, which makes it highly useful when the process under investigation does not yield much O. On the other hand, ABDA has a much lower reactivity, reacting with only 2% of the singlet oxygen generated in HO, as well as a smaller extinction coefficient, resulting in a much smaller spectroscopic response, but is soluble in neat water and is specific for O, allowing for discrimination from other reactive oxygen species. The results presented here not only allow a comparative assessment of the usefulness of the two O probes, but also provide a reference for an accurate absolute quantification of the amount of O generated in an experiment from the observed absorbance bleach.
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Direct combustion of waste oil in domestic stove by an internal heat re-circulation atomization technology: Emission and performance analysis.Direct use of waste oil as fuel to meet the residential energy demands, is very attractive due to its potentials to decrease fossil fuel consumption, reduce pollution and increase sustainability. This paper uses a domestic stove with an internal heat re-circulation and self-atomization technology to burn yellow waste cooking oil (WCO-1), brown waste cooking oil (WCO-2) and waste lubricant oil (WLO). Emission factors (EFs), energy efficiency and modified combustion efficiency (MCE) of this combined fuel/stove system were determined under space-heating and cooking modes. The results showed that EFs of CO, PM, total 16 PAHs and corresponding toxic equivalent quantity (TEQ) values ranged from 2.18 × 10 to 4.90 × 10 mg/MJ, 16.36-69.40 mg/MJ, 2.39-12.93 μg/MJ and 0.16-0.92 μg of TEQ/MJ. WCO-1 was verified to be the cleanest fuel with the highest energy efficiency (85.3 ± 3.3% and 90.4 ± 2.2%) and lowest emission levels, such as NO (53.75 ± 2.62 and 37.09 ± 5.41 mg/MJ), NO (82.40 ± 3.96 and 56.87 ± 8.29 mg/MJ) and PM (20.94 ± 6.55 and 16.35 ± 5.06 mg/MJ) compared to WCO-2 and WLO. The estimated total cost of using waste oil for each household in winter was much cheaper than some current available clean energy means, including only USD$ 400 of stove price and USD$ 250/ton of fuel per year. It is a promising candidate choice for replacing low-quality solid fuels in rural China and 2.62 million rural households would achieve environmental and economic benefits if promoting direct combustion of waste oil for daily heating and cooking.
2613 related Products with: Direct combustion of waste oil in domestic stove by an internal heat re-circulation atomization technology: Emission and performance analysis.Goat Anti-Human ACVR1, (i Goat Anti- SORBS1 ponsin Goat Anti-Human CDX2, (in Goat Anti-Human XBP1 TREB Goat Anti-Human FACT SUPT Goat Anti- SERPINB11, (in Goat Anti-Human SEPT7, (i Goat Anti-Human IGFBP3, ( Goat Anti-Human COG7, (in Goat Anti-Rat Myelin Prot Goat Anti-Mouse Pyruvate Goat Anti-Human Alpha2-an
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