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#32473550   2020/05/19 To Up

Eroded adjustable gastric band migration causing gastric obstruction and perforation in a pregnant lady.

The laparoscopic adjustable gastric band is the least invasive bariatric surgery, which has the advantage of preserving the anatomy of the gastrointestinal tract. In the last two decades, the laparoscopic adjustable gastric band (LAGB) has largely been replaced by other surgical techniques for weight loss because of its high inseparable complications. Although a popular surgical technique at the time of its introduction in 1993, LAGB nowadays reports for not more than 5.5% of all bariatric procedures. The estimated overall long term complication rates of LAGB are ranging from 0.1% to 28%.
Maram Alawad, Muhammad Abukhater, Khalid Al-Mohaimeed

2650 related Products with: Eroded adjustable gastric band migration causing gastric obstruction and perforation in a pregnant lady.

100.00 ug50μl1.00 flask100.00 ug100 μg

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#32473049   2020/05/30 To Up

Estimation of the Serial Interval and Basic Reproduction Number of COVID-19 in Qom, Iran, and Three Other Countries: A Data-Driven Analysis in the Early Phase of the Outbreak.

The outbreak of COVID-19 was first reported from China, and on February 19, 2020, the first case was confirmed in Qom, Iran. The basic reproduction number (R ) of infection is variable in different populations and periods. The present study aimed to estimate the R of COVID-19 in Qom, Iran and compare it with other countries. For estimation of the serial interval, we used data of the 51 confirmed cases of COVID-19 and their 318 close contacts in the Qom, Iran. The daily number of confirmed cases in the early phase of the outbreak and estimated serial interval were used for R estimation. We used the time-varying method as a method with the least bias to estimate R in Qom, Iran, China, Italy, and South Korea. The serial interval was estimated with gamma distribution, mean of 4.55 days and a standard deviation of 3.30 days for the COVID-19 epidemic based on Qom data. The number of R in the present study was estimated to be between 2 and 3 in Qom. Of the four countries studied, the lowest R was estimated for South Korea (1.5-2) and the highest for Iran (4-5). Sensitivity analyses demonstrated that R is sensitive to the applied mean generation time. To the best of the authors' knowledge, the current study is the first to estimate R number in Qom. To control the epidemic, the number of reproduction number should be reduced by decreasing the contact rate, decreasing transmission probability and decreasing the duration of the infectious period.
Mohammad Aghaali, Goodarz Kolifarhood, Roya Nikbakht, Hossein Mozafar Saadati, Seyed Saeed Hashemi Nazari

2934 related Products with: Estimation of the Serial Interval and Basic Reproduction Number of COVID-19 in Qom, Iran, and Three Other Countries: A Data-Driven Analysis in the Early Phase of the Outbreak.

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#32471890   2020/05/29 To Up

Clinical implementation of circulating tumour DNA testing for T790M for detection of treatment resistance in non-small cell lung cancer.

Epidermal growth factor receptor () T790M mutations can be detected in the circulating tumour DNA from plasma of patients with non-small cell lung cancer (NSCLC) to triage patients for osimertinib eligibility and monitor patients longitudinally for development of T790M-mediated resistance.
Tara Spence, Sheron Perera, Jessica Weiss, Sylvie Grenier, Laura Ranich, Frances Shepherd, Tracy L Stockley

2464 related Products with: Clinical implementation of circulating tumour DNA testing for T790M for detection of treatment resistance in non-small cell lung cancer.



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#32471789   2020/04/21 To Up

Regional differences in the management of cardiovascular risk factors among adults with diabetes: An evaluation of the Diabetes Collaborative Registry.

To compare cardiovascular risk factor control in adults with diabetes participating in a national diabetes registry to those in the general population and to ascertain regional differences in diabetes care.
Liane J Tinsley, Nathan D Wong, Jane E B Reusch, Suzanne V Arnold, Mikhail N Kosiborod, Yuanyuan Tang, Lori M Laffel, Sanjeev N Mehta

1868 related Products with: Regional differences in the management of cardiovascular risk factors among adults with diabetes: An evaluation of the Diabetes Collaborative Registry.

50 UG0.1 mg1 ml

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#32471505   2020/05/29 To Up

Real-time RT-PCR assay to detect Granada virus and the related Massilia and Arrabida phleboviruses.

Granada virus belongs to the genus Phlebovirus within the Naples serocomplex and was detected for the first time in sand flies from Spain in 2003. Seroprevalence studies have revealed that Granada virus may infect humans with most cases being asymptomatic. Moreover, recent studies in vector samples revealed that the related Massilia and Arrabida phleboviruses could be also circulating in Spain. The objective of this study was to develop and assess a new sensitive real-time RT-PCR assay for Granada virus diagnosis able to detect the related phleboviruses Massilia and Arrabida.
Laura Davó, Laura Herrero, Maria Paz Sánchez-Seco, Nuria Labiod, David Roiz, Elena Gómez-Díaz, Lourdes Hernandez, Jordi Figuerola, Ana Vázquez

1797 related Products with: Real-time RT-PCR assay to detect Granada virus and the related Massilia and Arrabida phleboviruses.

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#32471446   2020/05/29 To Up

Early circulating tumour DNA kinetics measured by ultra-deep next-generation sequencing during radical radiotherapy for non-small cell lung cancer: a feasibility study.

The evaluation of circulating tumour DNA (ctDNA) from clinical blood samples, liquid biopsy, offers several diagnostic advantages compared with traditional tissue biopsy, such as shorter processing time, reduced patient risk and the opportunity to assess tumour heterogeneity. The historically poor sensitivity of ctDNA testing, has restricted its integration into routine clinical practice for non-metastatic disease. The early kinetics of ctDNA during radical radiotherapy for localised NSCLC have not been described with ultra-deep next generation sequencing previously.
G M Walls, L McConnell, J McAleese, P Murray, T B Lynch, K Savage, G G Hanna, D Gonzalez de Castro

1814 related Products with: Early circulating tumour DNA kinetics measured by ultra-deep next-generation sequencing during radical radiotherapy for non-small cell lung cancer: a feasibility study.



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#32471423   2020/05/29 To Up

Once-daily single-inhaler versus twice-daily multiple-inhaler triple therapy in patients with COPD: lung function and health status results from two replicate randomized controlled trials.

The comparative efficacy of inhaled corticosteroid/long-acting muscarinic antagonist/long-acting β-agonist (ICS/LAMA/LABA) triple therapy administered via single or multiple inhalers in patients with chronic obstructive pulmonary disease (COPD) has not been evaluated comprehensively. We conducted two replicate trials comparing single- with multiple-inhaler ICS/LAMA/LABA combination in COPD.
Gary T Ferguson, Nicola Brown, Chris Compton, Thomas C Corbridge, Kelly Dorais, Charles Fogarty, Catherine Harvey, Morrys C Kaisermann, David A Lipson, Neil Martin, Frank Sciurba, Marjorie Stiegler, Chang-Qing Zhu, David Bernstein

2272 related Products with: Once-daily single-inhaler versus twice-daily multiple-inhaler triple therapy in patients with COPD: lung function and health status results from two replicate randomized controlled trials.



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#32471292   2020/05/27 To Up

Discovery of a Novel Mutation in DNA Gyrase and Changes in the Fluoroquinolone Resistance of over a 14-Year Period: A Single Center Study in Korea.

The efficacy of fluoroquinolone-based eradication therapy largely depends on the fluoroquinolone resistance of . The aim of this study was to investigate the changes in the primary resistance rate of to fluoroquinolone and the mechanism of resistance in Korea. A total of 153 strains and 48 strains of were isolated at a tertiary hospital in 2005/2006 and 2017/2018, respectively. The minimum inhibitory concentrations (MICs) of fluoroquinolone were determined by the serial 2-fold agar dilution method. DNA sequences in the quinolone resistance-determining regions of were analyzed in resistant strains. Subsequent natural transformation study was performed to determine the association between gyrase mutation and resistance. The resistance rates increased from 19.0% (29/153) to 43.8% (21/48) both for levofloxacin and moxifloxacin. The MIC values for resistant strains increased from 2-8 µg/mL to 4-16 µg/mL over time. Mutation of was detected in 93.1% (27/29) and 100% (21/21) among the resistant strains in both periods, respectively. A novel Gly-85 mutation of was found and confirmed to be associated with fluoroquinolone resistance. Fluoroquinolone resistance rate of has markedly increased over time in Korea. The resistance is mostly due to the point mutation of . Fluoroquinolone-containing regimens should be carefully selected in Korea, considering the increasing fluoroquinolone resistance.
Su Yeon Rhie, Jae Yong Park, Tae-Seop Shin, Jeong Wook Kim, Beom Jin Kim, Jae Gyu Kim

2783 related Products with: Discovery of a Novel Mutation in DNA Gyrase and Changes in the Fluoroquinolone Resistance of over a 14-Year Period: A Single Center Study in Korea.

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#32471139   2020/05/27 To Up

A Simulation Analysis of Nanofluidic Ion Current Rectification Using a Metal-Dielectric Janus Nanopore Driven by Induced-Charge Electrokinetic Phenomena.

We propose herein a unique mechanism of generating tunable surface charges in a metal-dielectric Janus nanopore for the development of nanofluidic ion diode, wherein an uncharged metallic nanochannel is in serial connection with a dielectric nanopore of fixed surface charge. In response to an external electric field supplied by two probes located on both sides of the asymmetric Janus nanopore, the metallic portion of the nanochannel is electrochemically polarized, so that a critical junction is formed between regions with an enriched concentration of positive and negative ions in the bulk electrolyte adjacent to the conducting wall. The combined action of the field-induced bipolar induced double layer and the native unipolar double layer full of cations within the negatively-charged dielectric nanopore leads to a voltage-controllable heterogenous volumetric charge distribution. The electrochemical transport of field-induced counterions along the nanopore length direction creates an internal zone of ion enrichment/depletion, and thereby enhancement/suppression of the resulting electric current inside the Janus nanopore for reverse working status of the nanofluidic ion diode. A mathematical model based upon continuum mechanics is established to study the feasibility of the Janus nanochannel in causing sufficient ion current rectification, and we find that only a good matching between pore diameter and Debye length is able to result in a reliable rectifying functionality for practical applications. This rectification effect is reminiscent of the typical bipolar membrane, but much more flexible on account of the nature of a voltage-based control due to induced-charge electrokinetic polarization of the conducting end, which may hold promise for osmotic energy conversion wherein an electric current appears due to a difference in salt concentration. Our theoretical demonstration of a composite metal-dielectric ion-selective medium provides useful guidelines for construction of flexible on-chip platforms utilizing induced-charge electrokinetic phenomena for a high degree of freedom ion current control.
Weiyu Liu, Yongjun Sun, Hui Yan, Yukun Ren, Chunlei Song, Qisheng Wu

2531 related Products with: A Simulation Analysis of Nanofluidic Ion Current Rectification Using a Metal-Dielectric Janus Nanopore Driven by Induced-Charge Electrokinetic Phenomena.

1 module1 module1 module1 module1 module100ug Lyophilized 15 ml 1 module 100ul1 module1 module

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#32470475   2020/05/26 To Up

Cost-effectiveness Analysis of Screening Extremely Low Birthweight Children for Hepatoblastoma Using Serum Alpha-fetoprotein.

To evaluate the cost-effectiveness of screening children born at extremely low birth weight (ELBW) for hepatoblastoma using serial serum alpha-fetoprotein (AFP) measurements.
Rebecca MacDonell-Yilmaz, Kelly Anderson, Bradley DeNardo, Philippa Sprinz, William V Padula

2937 related Products with: Cost-effectiveness Analysis of Screening Extremely Low Birthweight Children for Hepatoblastoma Using Serum Alpha-fetoprotein.

0.05 mg100ug Lyophilized50 KU1 kit(96 Wells)100ug Lyophilized100ug Lyophilized1ml1 kit(96 Wells)1mg100ug Lyophilized100ug Lyophilized100ug Lyophilized

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