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#33080637   2020/10/20 To Up

Evaluation of Interexaminer Variability in Video Head Impulse Test Results.

 The video head impulse test (vHIT) is a diagnostic tool to assess the function of the semicircular canals and branches of the vestibular nerve. The aim of this study was to analyze the interexaminer variability of vHIT results in healthy subjects.
Başak Mutlu, Sıdıka Cesur, Merve Torun Topçu, Cennet Reyyan Geçici, Öyküm Esra Aşkın, Emine Ufuk Derinsu

1035 related Products with: Evaluation of Interexaminer Variability in Video Head Impulse Test Results.

96 tests96 tests24 tests50 ul

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#33080565   2020/10/13 To Up

3D finite element models from serial section histology of skeletal muscle tissue - The role of micro-architecture on mechanical behaviour.

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R Kuravi, K Leichsenring, M Böl, A E Ehret

2240 related Products with: 3D finite element models from serial section histology of skeletal muscle tissue - The role of micro-architecture on mechanical behaviour.



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#33080045   2020/10/20 To Up

Exosomes and Extracellular Vesicles as Liquid Biopsy Biomarkers in Diffuse Large B-cell Lymphoma (DLBCL): Current State of the Art and Unmet Clinical Needs.

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's lymphoma, constituting biologically heterogeneous entities. Standard first line therapies cure ~60% of patients, the rest being either refractory or experiencing relapse. Currently, there are no robust predictive biomarkers of therapeutic response. Heterogeneity of DLBCL is partly explained by the cell of origin (COO), i.e. germinal center B cell (GCB) or activated B cell (ABC), with the latter exhibiting worse prognosis. While gene expression profiling (GEP) is the gold standard for determining COO, surrogate immunohistochemical algorithms are used clinically, but show significant discordance with GEP. Recently, additional subgroups with different prognoses have been reported. However, the tools/expertise required for analysis prohibit widespread deployment. Liquid biopsy-based assays show promise in providing clinically actionable information, are non-invasive and facilitate serial sampling to assess mechanisms of therapy resistance. Circulating, cell free DNA analysis has shown enhanced sensitivity, however, this modality cannot provide information on signaling pathways. Exosomes are endosomally derived vesicles, are found in high abundance in body fluids, and readily isolated using a variety of methods. Tumor derived exosomes contain genetic information and can reveal details for diagnostic, prognostic and therapeutic purposes in DLBCL. At present, standardized techniques for isolating exosomes are lacking and discriminating exosomes from neoplastic or normal B cells is challenging. Refinements in isolation procedures are required to realize their full potential as precision medicine tools to provide comprehensive information on disease subtypes, identify prognostic factors, allow real time monitoring of therapy response and to delineate drug targets.
Kenneth Ofori, Govind Bhagat, Alex J Rai

1360 related Products with: Exosomes and Extracellular Vesicles as Liquid Biopsy Biomarkers in Diffuse Large B-cell Lymphoma (DLBCL): Current State of the Art and Unmet Clinical Needs.

96 assays24 tests1 kit

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#33079761   2020/10/16 To Up

Orbital Compartment Syndrome After High-speed Air-Gasoline Blast Injury.

Orbital compartment syndrome is an ophthalmologic emergency that requires timely surgical intervention. The authors present a rare case of orbital compartment syndrome in a 30-year-old male injured by forceful entry of air-gasoline mixture into the orbit, secondary to inadvertent firing of the piston from running mechanical diagnostics on an automobile internal combustion engine. Orbital CT revealed extensive orbital emphysema with both pre- and postseptal involvement and diffuse chemical cellulitis. Serial exams revealed rapid deterioration of vision with elevated intraocular pressure and development of eyelid, corneal, and orbital edema; a relative afferent pupillary defect and optic nerve hypoperfusion. He was started on intravenous steroids and underwent an emergent lateral canthotomy with cantholysis, which temporarily reduced the intraocular pressure. However, a second rapid increase in soft tissue swelling resulted in another episode of ocular hypertension and compressive optic neuropathy, requiring emergent orbital bony decompression, which was followed by decreased intraocular and orbital pressure. The patient later developed progressive corneal opacification indicating delayed chemical injury. This was managed with a 10-day course of aggressive topical and systemic antiinflammatory agents with significant improvement in visual acuity. At last follow up, the vision was 20/30 and the corneal and eyelid edema had cleared.
Zhenyang Zhao, Amina Malik, Nita Bhat, Shruthi Harish Bindiganavile, Rahul T Pandit, Shaheen C Kavoussi, Andrew G Lee

1699 related Products with: Orbital Compartment Syndrome After High-speed Air-Gasoline Blast Injury.

96 tests8 Sample Kit 6 ml Ready-to-use 1ml100ug Lyophilized 500 ml 1

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#33078602   // To Up

USB capsule endoscope for retrograde imaging of the esophagus.

Endoscopes represent electro-optical devices that are used to visualize internal body cavities. The specialized endoscopic procedure of the upper gastrointestinal tract from the esophagus down to the duodenum is called an esophagogastroduodenoscopy.
Ivan Martincek, Peter Banovcin, Matej Goraus, Martin Duricek

1539 related Products with: USB capsule endoscope for retrograde imaging of the esophagus.

0.1 mg1 g250 mg 1 kit(s) 0.1 ml500 Units5 mg100ug100μg

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#33078441   2020/10/19 To Up

Utility of Mid-Upper Arm Circumference in Diagnosing Malnutrition in Children With Cystic Fibrosis.

Standardized diagnostic indicators for malnutrition using growth percentile z-scores (weight for length or body mass index [BMI]) and mid-upper arm circumference (MUAC) z-scores are being used in clinical practice; however, their application to the pediatric cystic fibrosis (CF) population is not well described. In this study, we aim to compare growth percentile z-scores and MUAC z-scores in diagnosing and classifying malnutrition in children with CF and assess the relationship between their degree of malnourishment and corresponding pulmonary function tests (PFTs).
Rachel Y Phong, Sandra L Taylor, Brandt A Robinson, Sanjay Jhawar, Kiran Nandalike

1959 related Products with: Utility of Mid-Upper Arm Circumference in Diagnosing Malnutrition in Children With Cystic Fibrosis.

100 μg2ug1 Set100 1 Set1 mg20 ul (10 mM)1 kit(96 Wells)

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#33078114   2020/10/18 To Up

Natural history of persistent subretinal fluid following the successful repair of rhegmatogenous retinal detachment.

To provide a detailed description of the natural history of persistent subretinal fluid (SRF) after successful repair of rhegmatogenous retinal detachment (RRD) and its association with visual outcome.
Yan Fu, Song Chen, Zhao-Hui Gu, Yue-Ling Zhang, Li-Ying Li, Na Yang

2261 related Products with: Natural history of persistent subretinal fluid following the successful repair of rhegmatogenous retinal detachment.

5 G 125 ml min 2 cartons1.00 flask100.00 ul5ml1200 units1ml1

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#33078097   2020/10/14 To Up

Analysis of 'earlyR' epidemic model and Time Series model for prediction of COVID-19 registered cases.

The COVID-19 is an epidemic that causes respiratory infection. The forecasted data will help the policy makers to take precautionary measures and to control the epidemic spread. The two models were adopted for forecasting the daily newly registered cases of COVID-19 namely 'earlyR' epidemic model and ARIMA model. In earlyR epidemic model, the reported values of serial interval of COVID-19 with gamma distribution have been used to estimate the value of R and 'projections' package is used to obtain epidemic trajectories by fitting the existing COVID-19 India data, serial interval distribution, and obtained R0 value of respective states. The ARIMA model is developed by using the 'auto.arima' function to evaluate the values of (p, d, q) and 'forecast' package is used to predict the new infected cases. The methodology evaluation shows that ARIMA model gives the better accuracy compared to earlyR epidemic model.
Karthick Kanagarathinam, Ebrahem A Algehyne, Kavaskar Sekar

1988 related Products with: Analysis of 'earlyR' epidemic model and Time Series model for prediction of COVID-19 registered cases.



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