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#32619921   2020/03/23 To Up

Novel FEMASK-score, a histopathologic assessment for destructive Charcot neuropathic arthropathy, reveals intraneural vasculopathy and correlates with progression and best treatment.

Charcot neuropathic arthropathy is a debilitating, rapidly destructive degenerative joint disease that occurs in diabetic, neuropathic midfoot. Clinicoradiologic assessment for Charcot neuropathic arthropathy previously relied on Eichenholtz stage. There is limited histopathologic data on this entity. We wanted to independently develop a histopathologic scoring system for Charcot neuropathic arthropathy.
Jesse King, Ben Murie, Julie C Fanburg-Smith, Chris Michael Stauch, Don Flemming, Michael J Klein, Elizabeth E Frauenhoffer, Madelaine Fritsche, Jessica D Smith, John Elfar, Michael Aynardi

1157 related Products with: Novel FEMASK-score, a histopathologic assessment for destructive Charcot neuropathic arthropathy, reveals intraneural vasculopathy and correlates with progression and best treatment.

10 mg50 ug 5 G2.5 mg200ug1 mg5mg100ug1,000 tests100ug100 mg

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#32619872   2020/06/17 To Up

Risk factors for developing heel ulcers for bedridden patients: A finite element study.

The heel is one of the most common sites of pressure ulcers and the anatomical location with the highest prevalence of deep tissue injury. Several finite element modeling studies investigate heel ulcers for bedridden patients. In the current study we have added the implementation of the calf structure to the current heel models. We tested the effect of foot posture, mattress stiffness, and a lateral calcaneus displacement to the contact pressure and internal maximum shear strain occurring at the heel.
W G H van Zwam, M C van Turnhout, C W J Oomens

1858 related Products with: Risk factors for developing heel ulcers for bedridden patients: A finite element study.

500 G0.1 mg10 mg0.1 mg100μg 100ul10ìg 1 G1 mg250 ml25 µg1 g

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#32619864   2020/06/19 To Up

Isolated limb perfusion for soft tissue sarcoma: Current practices and future directions. A survey of experts and a review of literature.

Soft tissue sarcomas constitute 1% of adult malignant tumors. They are a heterogeneous group of more than 50 different histologic types. Isolated limb perfusion is an established treatment strategy for locally advanced sarcomas. Since its adoption for sarcomas in 1992, after the addition of TNFα, few modifications have been done and although indications for the procedure are essentially the same across centers, technical details vary widely. The procedures mainly involves a 60 min perfusion with melphalan and TNFα under mild hyperthermia, achieving a limb preservation rate of 72-96%; with an overall response rates from 72 to 82.5% and an acceptable toxicity according to the Wieberdink scale. The local failure rate is 27% after a median follow up of 14-31 months compared to 40% of distant recurrences after a follow up of 12-22 months. Currently there is no consensus regarding the benefit of ILP per histotype, and the value of addition of radiotherapy or systemic treatment. Further developments towards individualized treatments will provide a better understanding of the population that can derive maximum benefit of ILP with the least morbidity.
K S Martin-Tellez, W J van Houdt, F van Coevorden, C Colombo, M Fiore

2942 related Products with: Isolated limb perfusion for soft tissue sarcoma: Current practices and future directions. A survey of experts and a review of literature.

96 wells (1 kit)50 ug 1 g0.1ml (1mg/ml)100 mg100ul

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#32619735   2020/06/30 To Up

Panton-Valentine leukocidin positive Staphylococcus aureus in skin and soft tissue infections from primary care patients.

To characterise deep skin and soft tissue infections (dSSTI) caused by Panton-Valentine leukocidin positive (PVL) vs. PVL-negative (PVL) Staphylococcus aureus isolates.
Johannes Friesen, Robert Neuber, Jörg Fuhrmann, Heike Kietzmann, Thilo Wenzel, Frieder Schaumburg, Michael Müller, Ralf Ignatius

1608 related Products with: Panton-Valentine leukocidin positive Staphylococcus aureus in skin and soft tissue infections from primary care patients.



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#32619653   2020/06/30 To Up

Analysis on the diagnosis of infection risk factors and the incidence of ureteroscopy holmium laser lithotripsy and vagal excitation under computed tomography image information health technology.

It was to explore the corresponding preventive measures based on the analysis of the main risk factors of systemic inflammatory response syndrome (SIRS) after the ureteroscopy holmium laser lithotripsy, so as to reduce the incidence rate of postoperative SIRS and vagal nerve excitement in patients with renal stones. 148 patients treated with the ureteroscopy holmium laser lithotripsy in our hospital from January 2018 to December 2019 were selected as the research objects. The total abdominal computed tomography (CT) plain scan and three-dimensional imaging were used for examination before surgery, and the Kidney, ureter, bladder (KUB) was used to evaluate the treatment effects after surgery. The objects were divided into the large stone group (>20mm) and the small stone group (≤20mm). The differences in stone sites and stone length and diameter between the age and sex of patients in the two groups were recorded and compared, and the stone clearance rate and complications in the two groups were evaluated. Through the Pearson chi-square test and multivariate Logistic regression analysis of the risk factors related to postoperative SIRS, the occurrence of vagal excitation in patients after ureteral soft mirror holmium laser lithotripsy was analysed, it found that there was no statistical difference in stone sites of age and sex between the two groups (P>0.05), and there was no statistical difference in stone clearance rate and postoperative complications between the two groups (P>0.05), while the difference in operation time between the two groups was statistically significant (P<0.05). According to the regression analysis, there was a significant positive correlation between the time of operation, positive urine culture in the middle before operation, infectious calculus, and postoperative SIRS (P<0.05). 78 patients suffered from vagal excitation during the surgery, and the incidence rate was 52.7%. The results showed that the treatment of kidney stones with a diameter more than 20mm and no more than 20mm by holmium laser lithotripsy under ureter-scope had good clinical effect. The operative time, positive urine culture in the middle part of the operation, and infectious stones were included in the main risk factors for the occurrence of SIRS after ureter-scope holmium laser lithotripsy and has a certain impact on the renal nerve trunk while crushing stones.
Yuelong Zhang, Qi Zhang, Jia Lv, Dahong Zhang

2893 related Products with: Analysis on the diagnosis of infection risk factors and the incidence of ureteroscopy holmium laser lithotripsy and vagal excitation under computed tomography image information health technology.

110 mg2100.00 ul100 mg100ug 15 ml 200ul25 mg

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#32619605   2020/06/30 To Up

A Systematic Review and Meta-Analysis of Biceps Tenodesis Fixation Strengths: Fixation Type and Location Are Biomechanically Equivalent.

The purpose of this meta-analysis and systematic review was to critically evaluate the biomechanical outcomes of different fixation constructs for a variety of biceps tenodesis techniques in cadaveric models based on both type of fixation as well as location.
Travis J Dekker, Liam A Peebles, Fletcher R Preuss, Brandon T Goldenberg, Grant J Dornan, Matthew T Provencher

2915 related Products with: A Systematic Review and Meta-Analysis of Biceps Tenodesis Fixation Strengths: Fixation Type and Location Are Biomechanically Equivalent.

96T100ul25 mg10 mg5mg100ug500 MG50 mg25 mg1,000 tests10 mg1000 tests

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#32619438   2020/06/30 To Up

Appendageal Tumors and Tumor-Like Lesions of the Testis and Paratestis: A 32-Years of Experience at a Single Institution.

The testicular hilum and paratestis contain several embryologically diverse anatomic structures, including the spermatic cord, tunica vaginalis, epididymis, rete testis, and several other embryonic remnants. Several benign and malignant lesions arise from these morphologically distinct structures, and, due to their proximity, it is challenging to classify and subsequently stage these tumors. Herein, we conducted a retrospective review of the paratesticular appendageal and rete testis tumors and tumor-like lesions diagnosed at our department from 1985 to 2016. Soft tissue lesions/tumors were excluded. A total of 146 paratesticular appendageal and rete testis tumors and tumor-like lesions were identified. Most were benign (n=107; 73%). Adenomatoid tumor (26%) was the most common benign tumor, followed by different types of cysts (19%), mesothelial hyperplasia (18%), serous cystadenoma (5.5%) and rete testis adenoma (4%). Malignant lesions comprised 23%, with mesothelioma the most common (15%), adenocarcinoma of the rete testis (4%), serous cystadenocarcinoma (2%), and papillary and clear cell adenocarcinoma of the epididymis (2%). Finally, serous borderline tumors and melanotic neuroectodermal tumor (retinal anlage tumors) comprised the remaining 4% of cases. In conclusion, a wide range of benign and malignant lesions can arise from the paratesticular region. Awareness of these lesions and their histologic spectrum is crucial to avoid diagnostic pitfalls and to allow pathologists to establish a correct diagnosis and subsequent treatment plan.
Khaleel I Al-Obaidy, Fatimah I Alruwaii, Thomas M Ulbright, Muhammad T Idrees

1727 related Products with: Appendageal Tumors and Tumor-Like Lesions of the Testis and Paratestis: A 32-Years of Experience at a Single Institution.

5mg1,000 tests100ul1 mg1000 TESTS/0.65ml25 mg1000 tests200ug100ug10 mg

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#32619387   2020/07/03 To Up

species infections in humans: a systematic review.

species have been recognized to cause infections in immunocompromised individuals. The purpose of this study was to systemically review all published cases of infections in humans and describe the epidemiology, microbiology, antimicrobial susceptibility, treatment and outcomes of these infections in humans. We performed a systematic review of PubMed (through 20 Octrober 2019) for studies providing epidemiological, clinical, microbiological as well as treatment data and outcomes of species infections. A total of 37 studies, containing data of 99 patients, were included in the analysis. The most common infections were those of the bloodstream in 74.7% (74 patients), musculoskeletal infections in 8.1% (8 patients), skin and soft tissue infections (SSTIs) and peritoneal dialysis-associated peritonitis in 6.1% (6 patients) each. Epidemiology of these infections differed, with bacteremias being more prevalent in patients with malignancy and central venous lines, musculoskeletal infections being more prevalent after orthopedic surgery, and SSTIs occurring without any reported underlying cause. Resistance to beta-lactams was very high with penicillin, piperacillin/tazobactam resistance and cephalosporin resistance at 96.6%, 90.7% and 77.8% respectively, while quinolone resistance was 9.1%. Quinolones, carbapenems and cephalosporins are the most common agents used for treatment, irrespectively of the infection site. Overall mortality was 3% (3 patients), with the mortality attributed to being at 1% (1 patient).
Petros Ioannou, Vasiliki Mavrikaki, Diamantis P Kofteridis

2981 related Products with: species infections in humans: a systematic review.

50ul 100ul1 Product tipe: Instrumen 100ul 100ul50ul 100ul 100ul 100ul96T96T 100ul

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#32619210   2020/07/03 To Up

Intrinsic Laryngeal Lipoma Treated with Transoral CO₂ Laser Microsurgery: An Unusual Case Report.

BACKGROUND Lipomas, the most common soft tissue tumors, represent almost half of all benign mesenchymal neoplasms and are characterized by the absence of symptoms. However, if they grow in a laryngeal site, they can cause dyspnea and dysphonia which represents one of the major symptoms of benign laryngeal diseases (such as polyps or nodules); these symptoms are often the first symptom of neoplastic diseases. CASE REPORT We present a case of a 28-year-old female patient with a rounded pseudocyst neoformation located in the left aryepiglottic fold that partially hid the homolateral vocal cord and limited its mobility. Due to the site of the lesion and MRI images showing a well-capsulated neoformation without contrast enhancement, we decided to surgically remove it with a micro-laryngoscopic approach after an evaluation of the patient's upper airway by an anesthetist. This case demonstrates that a micro-endoscopic approach using transoral laser microsurgery for surgical excision was useful for removing the entire mass and avoiding relapses. CONCLUSIONS Laryngeal lipomas are benign and rare lesions, in particular intrinsic lipomas are uncommon, but, if they grow, they can cause life-threatening symptoms. In our case, a lipoma reached a size of around 2 centimeters and was not pedunculated, only a histopathological examination of the surgical specimens could provide a differential diagnosis against a lipoma-like liposarcoma. The use of Transoral Laser CO₂ Micro-laryngoscopy (TLM) provided good management of a small intrinsic lipomas of the larynx, minimizing the potential for relapses.
Nicola Lombardo, Nadia Lobello, Giovanna Piazzetta, Marco Ciriolo, Corrado Pelaia, Domenico Testa, Gaetano Motta

1273 related Products with: Intrinsic Laryngeal Lipoma Treated with Transoral CO₂ Laser Microsurgery: An Unusual Case Report.

0.1 ml

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#32618991   2020/07/03 To Up

Primitive chain network simulations for the interrupted shear response of entangled polymeric liquids.

The non-linear viscoelastic response under interrupted shear flows is one of the interesting characteristics of entangled polymers. In particular, the stress overshoot in the resumed shear has been discussed concerning the recovery of the entanglement network in some studies. In this study, we performed multichain slip-link simulations to observe the molecular structure of an entangled polymer melt. After confirming the reasonable reproducibility of our simulation with the literature data, we analyzed the molecular characteristics following the decoupling approximation. We reasonably found that the segment orientation dominates the stress overshoot even under the resumed shear with minor contributions from the segment stretch and entanglement density. We defined the mitigation function for the recovery of the stress overshoot as a function of the rest time and compared it with the relaxation of the molecular quantities after the initial shear. As a result, we have found that the mitigation of the stress overshoot coincides with the relaxation of entanglement density.
Yuichi Masubuchi, Yuya Doi, Takashi Uneyama

1237 related Products with: Primitive chain network simulations for the interrupted shear response of entangled polymeric liquids.

1 mg100μg96T1 1 G 25 G6 ml1 mg10 mgmin 2 cartons1 mg

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