Search results for: striated
#34525367 // To Up
Mechanical buckling can pattern the light-diffracting cuticle of Hibiscus trionum.Many species have cuticular striations that play a range of roles, from pollinator attraction to surface wettability. In Hibiscus trionum, the striations span multiple cells at the base of the petal to form a pattern that produces a type of iridescence. It is postulated, using theoretical models, that the pattern of striations could result from mechanical instabilities. By combining the application of mechanical stress with high-resolution imaging, we demonstrate that the cuticle buckles to create a striated pattern. Through mechanical modeling and cryo-SEM fractures, we show that the cuticle behaves like a bilayer system with a stiff film on a compliant substrate. The pattern of buckling aligns with the direction of the stress to create a larger-scale pattern. Our findings contribute to the understanding of the formation of tissue-wide patterns in living organisms.
Chiara A Airoldi, Carlos A Lugo, Raymond Wightman, Beverley J Glover, Sarah Robinson
2616 related Products with: Mechanical buckling can pattern the light-diffracting cuticle of Hibiscus trionum.
#34516638 // To Up
A NEW SPECIES OF ALLINTOSHIUS (NEMATODA: HELIGMOSOMOIDEA) FROM TWO SPECIES OF BATS IN BRAZIL.Allintoshius Chitwood, 1937 is the only genus of the family Ornithostrongylidae (Travassos, 1937) Durette-Desset and Chabaud, 1981 that parasitizes bats. Currently, there are 10 valid species in the genus, of which 3 were described from Brazil. This study describes a new species of Allintoshius and records the first occurrence of a nematode of this genus parasitizing Artibeus lituratus (Olfers). Allintoshius gomesae n. sp. is characterized by having anterior region coiled, cephalic vesicle with cuticular dilation striated transversely, and claviform esophagus. Synlophe in females consists of 16 cuticular ridges at the mid-body. Males have large caudal bursa, and conic and small spicules, and the gubernaculum is absent. Females have uterus didelphic, amphidelphic, tail tip tapered, and ovijector divided into 2 divergent branches, subequal in length. The new species differs from its congeners especially by the shape of the tail tip, vulvar opening, and size of spicules. Allintoshius gomesae is the fourth species of Allintoshius from Brazil and the first report in Ar. lituratus, increasing the number of species recognized of the genus.
Thayane Ferreira Fernandes, Francisco Tiago de Vasconcelos Melo, Jeannie Nascimento Dos Santos
2868 related Products with: A NEW SPECIES OF ALLINTOSHIUS (NEMATODA: HELIGMOSOMOIDEA) FROM TWO SPECIES OF BATS IN BRAZIL.100ul96T 100ul 100ul50 ug 100ul96T 100ul50ul 100ul50 ug 100ul
#34502512 2021/09/04 To Up
Cilia, Centrosomes and Skeletal Muscle.Primary cilia are non-motile, cell cycle-associated organelles that can be found on most vertebrate cell types. Comprised of microtubule bundles organised into an axoneme and anchored by a mature centriole or basal body, primary cilia are dynamic signalling platforms that are intimately involved in cellular responses to their extracellular milieu. Defects in ciliogenesis or dysfunction in cilia signalling underlie a host of developmental disorders collectively referred to as ciliopathies, reinforcing important roles for cilia in human health. Whilst primary cilia have long been recognised to be present in striated muscle, their role in muscle is not well understood. However, recent studies indicate important contributions, particularly in skeletal muscle, that have to date remained underappreciated. Here, we explore recent revelations that the sensory and signalling functions of cilia on muscle progenitors regulate cell cycle progression, trigger differentiation and maintain a commitment to myogenesis. Cilia disassembly is initiated during myoblast fusion. However, the remnants of primary cilia persist in multi-nucleated myotubes, and we discuss their potential role in late-stage differentiation and myofiber formation. Reciprocal interactions between cilia and the extracellular matrix (ECM) microenvironment described for other tissues may also inform on parallel interactions in skeletal muscle. We also discuss emerging evidence that cilia on fibroblasts/fibro-adipogenic progenitors and myofibroblasts may influence cell fate in both a cell autonomous and non-autonomous manner with critical consequences for skeletal muscle ageing and repair in response to injury and disease. This review addresses the enigmatic but emerging role of primary cilia in satellite cells in myoblasts and myofibers during myogenesis, as well as the wider tissue microenvironment required for skeletal muscle formation and homeostasis.
Dominic C H Ng, Uda Y Ho, Miranda D Grounds100ul200ul10 mg200ul5 mg1 mg100ul10 mg 6 ml Ready-to-use 5 G100ul
#34492609 2021/08/28 To Up
Pelvic-floor function, dysfunction, and treatment.The pelvic floor functions as a holistic entity. The organs, bladder, bowel, smooth and striated muscles, nerves, ligaments and other connective tissues are directed cortically and reflexly from various levels of the nervous system. Such holistic integration is essential for the system's multiple functions, for example, pelvic girdle stability, continence, voiding/defecation, and sexuality. Pelvic floor dysfunction (PFD) is related to a variety of pelvic pain syndromes and organ problems of continence and evacuation. Prior to treatment, it is necessary to understand which part(s) of the system may be causing the dysfunction (s) of Chronic Pelvic Pain Syndrome (CPPS), pelvic girdle pain, sexual problems, Lower Urinary Tract Symptoms (LUTS), dysfunctional voiding, constipation, prolapse and incontinence. The interpretation of pelvic floor biomechanics is complex and involves multiple theories. Non-surgical treatment of PFD requires correct diagnosis and correctly supervised pelvic floor training. The aims of this review are to analyze pelvic function and dysfunction. Because it is a holistic and entirely anatomically based system, we have accorded significant weight to the Integral Theory's explanations of function and dysfunction.
JÃ¶rgen Quaghebeur, Peter Petros, Jean-Jacques Wyndaele, Stefan De Wachter200ul2.5 mg10 mg200.00 ug100 mg100ug25 mg50 ug 100 mg200.00 ug 25 MG100ul
#34488242 2021/09/06 To Up
Urethral function and failure: A review of current knowledge of urethral closure mechanisms, how they vary, and how they are affected by life events.A critical appraisal of the literature regarding female urethral function and dysfunction is needed in light of recent evidence showing the urethra's role in causing stress and urge urinary incontinence.
Fernanda Pipitone, Zhina Sadeghi, John O L DeLancey
2430 related Products with: Urethral function and failure: A review of current knowledge of urethral closure mechanisms, how they vary, and how they are affected by life events.5mg25 mg2.5 mg100 mg 25 MG100ug10 mg50 ug 100ug25 mg100ul
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[Acute kidney injury caused by rhabdomyolysis as a SARS-CoV-2 infection manifestation. Report of one case].SARS-CoV-2 infection has a wide spectrum of clinical manifestations secondary to the impairment of different organs, including kidney. Rhabdomyolysis is produced by disintegration of striated muscle and the liberation of its contents to the extracellular fluid and bloodstream. This may produce hydro electrolytic disorders and acute kidney injury. We report a 35-year-old female with a history of SARS-CoV-2 infection who was hospitalized because of respiratory failure and developed renal failure. The etiologic study showed elevated total creatine kinase levels and a magnetic resonance imaging confirmed rhabdomyolysis. The patient required supportive treatment with vasoactive drugs, mechanic ventilation and kidney replacement therapy. She had a favorable evolution with resolution of respiratory failure and improvement of kidney function.
Javier PÃ©rez, SebastiÃ¡n SÃ¡nchez, Rodrigo A SepÃºlveda, Magdalena Vera, Pablo Mery, Bernardita Garayar, Roberto Jalil
2686 related Products with: [Acute kidney injury caused by rhabdomyolysis as a SARS-CoV-2 infection manifestation. Report of one case].200ul5/100 Packing /sleeve/bo100 plates200 assays200ul100 tests200ul200ul
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Flagellate Dermatitis due to Bleomycin Intake.Flagellate dermatitis is a rare cutaneous manifestation in which long, striated erythematous lesion appear on the patient's skin. It is most frequently associated with bleomycin treatment or Shiitake mushroom intake, but it may also be attributed to many other possible causes. Herein we present a case of striated, hyperpigmented lesions which occurred after bleomycin intake. The typical flagellate lesions appeared for the first time on the patient's back and shoulders after the first course of chemotherapy for seminoma (bleomycin, etoposide, and cisplatin). The active lesions disappeared with the discontinuation of chemotherapy. Clinicians should be aware of flagellate pattern of dermatitis which may accompany different clinical situations.
Piotr K Krajewski, Åukasz Matusiak, Jacek C Szepietowski25 mg0.5mg 50G500 mg1 ml51 module100 ug1 moduleOne 96-Well Strip Micropl 1KG
#34466346 // To Up
Mild congenital myopathy due to a novel variation in gene.Centronuclear myopathies (CNMs) are a subgroup of congenital myopathies (CMs) characterized by muscle weakness, genetic heterogeneity, and predominant type 1 fibers and increased central nuclei in muscle biopsy. Mutations in CNM-causing genes such as , , , , , , and extraordinary rarely (striated muscle preferentially expressed protein kinase) have been identified for about 60-80% of patients. Herein, we report a case of CM due to a novel variation in the gene, manifested by mild neonatal hypotonia, muscle weakness, delayed motor milestones, and ophthalmoplegia, without dilated cardiomyopathy. We identified a novel variation [c.153C>T (p.Asn51=) in exon 1] in the gene with whole-exome sequencing and confirmed by Sanger sequencing. Mild intellectual disability has not been associated with SPEG-related CM in the previous reports. We suggest that this report expands the phenotypic spectrum of SPEG-related CM, and further case reports are required to expand the genotype-phenotype correlations.
Mirac Yildirim, Ozgur Balasar, Engin Kose, Melih Timucin Dogan100 μg1 kit100 100 300 units1 mg25
#34462952 2021/08/31 To Up
Histometric parameters of the large intestine of hybrid marmosets Callithrix sp. under the influence of seasonality.Morphofunctional characteristics of the large intestine are rarely explored to understand the physiology, behavior and ecology of neotropical primates. In this study, we analyzed the histometric parameters of the large intestine of hybrid marmosets (Callithrix sp.) captured in forest fragments of ViÃ§osa-Brazil, under seasonal interference. These animals were predominantly insectivorous in the rainy season and gummivores in the dry season. Large intestine fragments were collected and processed according to histological methods and stained with toluidine blue for general analysis, periodic acid of Schiff (PAS) and Alcian blue (AB) for goblet cells, Grimelius and Masson Fontana for argyrophil and argentaffin endocrine cells. Several histometric parameters were more expressive in the large intestine of the rainy season marmosets: greater thickness of the parietal layers, greater number of argyrophil and argentaffin endocrine cells, and AB-positive goblet cells, characteristics favor secretomotor functions and reduce the passage time of the fecal bolus, which is consistent with an insectivorous diet. In contrast, parameters such as crypt width, height of the absorptive cells and striated border, and the number of PAS-positive cells were more expressive in the dry season marmosets, reflecting the need for longer passage time for digestion and absorption of food items from tree gum, which are more complex and demand the action of microorganisms present in the large intestine, as well as greater protection against the abrasive action of dietary fibers and against microorganisms. Thus, it can be said that the marmoset's large intestine has morphological adaptations to maximize energy intake from the diet, which alternates under the influence of seasonality.
Vanessa de Paula GuimarÃ£es-Lopes, Maria Raquel Varino SÃ¡ Gomes, Mislene Kagueyama, Rita de CÃ¡ssia Vieira Faria, Oswaldo Pinto Ribeiro Filho, Fabiano Rodrigues de Melo, Sirlene Souza Rodrigues Sartori
2942 related Products with: Histometric parameters of the large intestine of hybrid marmosets Callithrix sp. under the influence of seasonality.5 G500 Units1121 ml150 IU100.00 ul
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