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#32650348   2020/07/10 To Up

[The German-Language Version of the Muscle Dysmorphia Inventory: Evaluation of the Psychometric Properties in Male Samples].

To assess central aspects of muscle dysmorphia, classified as a subtype of body dysmorphic disorder, the Muscle Dysmorphia Inventory (MDI) is available for the English-speaking areas. The aim of the present study was to evaluate the psychometric properties of the German-language version of the MDI. Therefore, male participants from two separate samples (sample 1: n=143; sample 2: n=71; N=214) completed a questionnaire battery, including the MDI. Using confirmatory factor analysis, the factor structure postulated by the authors of the English-language original version could not be replicated. However, the fit indices were broadly adequate when the model was altered based on the modification indices. The MDI subscales showed acceptable to excellent internal consistencies. The test-retest reliability of approximately 14 days was high. Significant positive correlations of the MDI subscales with other body image and psychopathology measures, and the weight-training frequency per week indicated good convergent and criterion validity. Furthermore, the MDI differentiated between subgroups of men with muscle dysmorphia, weight-training, and non-weight-training men. With the exception of the subscale Pharmacological Use (PU), which showed lower reliability and validity, and the insufficient model fit, the German-language version of the MDI generally displayed adequate psychometric properties. Hence, with restrictions concerning the subscale PU, the administration in clinical-psychological research and a psychotherapeutic context seems to be recommendable.
Rike Arkenau, Manuel Waldorf, Martin Cordes, Silja Vocks

2450 related Products with: [The German-Language Version of the Muscle Dysmorphia Inventory: Evaluation of the Psychometric Properties in Male Samples].

1 100ul

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#32650342   2020/07/10 To Up

Protective Role of EGCG Against Malathion Induced Genotoxicity Using Human Lymphocytes.

Green tea (), which is the most common drink across the world after water, has many antioxidant properties. Epigallocatecin-3-gallate (EGCG) is a flavonoid which accounts for 33-50% of green tea solids. It functions as a powerful antioxidant, preventing oxidative damage in healthy cells, with antiangiogenic and antitumor activities and as a modulator of tumor cell response to chemotherapy. Malathion is an organophosphate pesticide which is widely used in agriculture, veterinary and industries. Oxidative stress has been identified as one of malathion's main molecular mechanisms. The purpose of this study was to evaluate protective role of EGCG against malathion induced genotoxicity using human lymphocyte model. Blood samples from 8 non-smoker healthy volunteers with no history of chemotherapy were collected and divided into six groups: Control, EGCG (50 µM), EGCG (20 µM), Malathion (24 µM), EGCG (50 µM)+Malathion (24 µM) and EGCG (20 µM)+Malathion (24 µM). For genotoxicity assay, we employed micronuclei test. For antioxidant capacity evaluation, GSH content and MDA levels were measured. Malathion showed significant genotoxic damage compared to the intact lymphocytes, however, treatment with EGCG at both concentrations were reduced the genotoxic effect of malathion. Malathion induced lipid peroxidation, while pre-treatment with EGCG at both concentrations, significantly protected the lymphocytes against malathion induced lipid peroxidation. Malathion significantly reduced GSH content, but pre-treatment with EGCG significantly recovered GSH content. Overall this study demonstrated that EGCG (at both concentrations) significantly prevents human lymphocytes against malathion induced genotoxicity and oxidative damage.
Seyed Mousa Taghavi, Amir Shadboorestan, Samin Sabzevari, Maryam Gholami, Razieh Keshavarz-Maleki, Hossein Mozdarani, Seyed Nasser Ostad, Omid Sabzevari

1537 related Products with: Protective Role of EGCG Against Malathion Induced Genotoxicity Using Human Lymphocytes.

100 ul 100 UG100 5 x 50 ug200 100 extractions 100ul50 ul1 mg200 5ug50 ug

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#32650328   2020/07/10 To Up

Poly(ester amide) microspheres are efficient vehicles for long-term intracerebral growth factor delivery and improve functional recovery after stroke.

Growth factors promote plasticity in injured brain and improve impaired functions. For clinical application, efficient approaches for growth factor delivery into the brain are necessary. Poly(ester amide) (PEA)-derived microspheres (MS) could serve as vehicles due to their thermal and mechanical properties, biocompatibility and biodegradability. Vascular endothelial growth factor (VEGF) exerts both vascular and neuronal actions, making it suitable to stimulate post-stroke recovery. Here, PEA (composed of adipic acid, L-phenyl-alanine and 1,4-butanediol) MS were loaded with VEGF and injected intracerebrally in mice subjected to cortical stroke. Loaded MS provided sustained release of VEGF in vitro and, after injection, biologically active VEGF was released long-term, as evidenced by high VEGF immunoreactivity, increased VEGF tissue levels, and higher vessel density and more NG2+ cells in injured hemisphere of animals with VEGF-loaded as compared to non-loaded MS. Loaded MS gave rise to more rapid recovery of neurological score. Both loaded and non-loaded MS induced improvement in neurological score and adhesive removal test, probably due to anti-inflammatory action. In summary, grafted PEA MS can act as efficient vehicles, with anti-inflammatory action, for long-term delivery of growth factors into injured brain. Our data suggest PEA MS as a new tool for neurorestorative approaches with therapeutic potential.
Tamar Memanishvili, Emanuela Monni, Jemal Tatarishvili, Olle Lindvall, Alexander Tsiskaridze, Zaal Kokaia, Daniel Tornero

1386 related Products with: Poly(ester amide) microspheres are efficient vehicles for long-term intracerebral growth factor delivery and improve functional recovery after stroke.

100μg0.1 mg20 ug5x10 ug10 mg2ug1 mg5 ml100.00 ug100 ug20 ug96 wells (1 kit)

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#32650322   2020/07/10 To Up

Non-random distribution of vacuoles in.

A central question in eukaryotic cell biology asks, during cell division, how is the growth and distribution of organelles regulated to ensure each daughter cell receives an appropriate amount. For vacuoles in budding yeast, there are well described organelle-to-cell size scaling trends as well as inheritance mechanisms involving highly coordinated movements. It is unclear whether such regulation is necessary in the symmetrically dividing fission yeast, Schizosaccharomyces pombe, in which random partitioning may be utilized to distribute vacuoles to daughter cells. To test this idea, we utilized machine learning to develop automated methods for segmenting fission yeast cells and locating vacuoles in live fission yeast cells from brightfield and fluorescence micrographs. We have found that the scaling trends of vacuole number, volume and surface area-to-cell size is consistent across a variety of strains, and that vacuole proliferation is a key mechanism for vacuole growth. We also show that vacuoles are not distributed evenly throughout the cell with respect to available cytoplasm. Rather, vacuoles show distinct peaks in distribution close to the nucleus, and this clustering was confirmed in mutants in which nucleus position is perturbed. Future work will establish the molecular mechanism for this clustering.
William Chadwick, Sujoy Biswas, Simone Bianco, Yee-Hung Mark Chan

2997 related Products with: Non-random distribution of vacuoles in.

25 ug 5 G

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#32650305   2020/07/10 To Up

Self-reported symptoms of SARS-CoV-2 infection in a non-hospitalized population: results from the large Italian web-based EPICOVID19 cross-sectional survey.

Understanding the occurrence of Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2)-like symptoms in a large non-hospitalized population, when the epidemic peak was occurring in Italy, is of paramount importance but data are scarce.
Fulvio Adorni, Federica Prinelli, Fabrizio Bianchi, Andrea Giacomelli, Gabriele Pagani, Dario Bernacchia, Stefano Rusconi, Stefania Maggi, Caterina Trevisan, Marianna Noale, Sabrina Molinaro, Luca Bastiani, Loredana Fortunato, Nithiya Jesuthasan, Aleksandra Sojic, Carla Pettenati, Marcello Tavio, Massimo Andreoni, Claudio Mastroianni, Raffaele Antonelli Incalzi, Massimo Galli

1055 related Products with: Self-reported symptoms of SARS-CoV-2 infection in a non-hospitalized population: results from the large Italian web-based EPICOVID19 cross-sectional survey.

250ul1x107 IFU/ml x 200ul50 mg100ug Lyophilized25mg

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#32650295   2020/07/07 To Up

Evaluation of the learning curve for laparoscopic pancreatoduodenectomy by CUSUM analyses. Cohort study.

Laparoscopic pancreatoduodenectomy (LPD) remains an extremely demanding surgery. The purpose of this study was to describe the learning curve required for its safe implementation.
O Morató, I Poves, F Burdío, P Sánchez-Velázquez, X Duran, L Grande

1754 related Products with: Evaluation of the learning curve for laparoscopic pancreatoduodenectomy by CUSUM analyses. Cohort study.

100ul 100 G 50 UG100 mg10 mg0.1 mg1 g5 g 100ul

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#32650292   2020/07/07 To Up

Modeling crash risk of horizontal curves using large-scale auto-extracted roadway geometry data.

Highway horizontal curves (H-curves) provide a smooth transition between two tangent sections of roadways. They allow vehicles to adjust their travel directions gradually. However, the geometry changes of the highway sections with H-curves often raise safety concerns. In order to deploy effective safety countermeasures, a critical task is to understand the risk factors associated with H-curves. Existing studies have made efforts to probe the safety issues associated with H-curves, whereas they were limited to relatively small-scale examinations because of the challenges in identifying H-curves from large road networks. In addition, due to the lack of well-archived traffic and roadway information, gathering other data associated with the H-curves is also difficult. Regarding to these gaps, this study aims to leverage open-source data to analyze the crash risk of highway sections with H-curves. In particular, the present study highlights itself from two main aspects: (i) a H-curve extraction tool was developed to facilitate large-scale curve data collection through the analytics of different open source data; and (ii) a crash modeling framework was developed to quantify H-curve crash risk. A case study based on a statewide road network was performed to test the developed crash risk models with the collected curve data. The results show the opportunities of using the developed tool for large-scale data collection and analyze the safety impacts of H-curve geometric properties, elevation change, traffic exposure, among others. Findings of this study provide insights into the improvement of H-curve data collection and safety evaluation.
Qingyu Ma, Hong Yang, Zhenyu Wang, Kun Xie, Di Yang

1612 related Products with: Modeling crash risk of horizontal curves using large-scale auto-extracted roadway geometry data.

Labels 2 mg of Ab1 kit100 ug1x107 IFU/ml x 200ul

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#32650290   2020/07/07 To Up

Validity testing in veterans with epileptic seizures and psychogenic nonepileptic seizures.

Identification of clinically meaningful subgroups among patients with psychogenic nonepileptic seizures (PNES) or epileptic seizures (ES) is of potential value for assessing prognosis and predicting therapeutic response. Invalid performance on validity tests has been associated with noncredible complaints and worse cognitive test scores, and may be one such classification criteria. We studied invalid performance in Veterans with PNES or ES, and the association of invalid performance with cognitive test scores and subjective complaints.
Martin Salinsky, Laurence Binder, Daniel Storzbach, Karen Parko, Paul Rutecki, Elizabeth Goy, Sandy Tadrous-Furnanz

1844 related Products with: Validity testing in veterans with epileptic seizures and psychogenic nonepileptic seizures.

100 μg100 μg 1 G5 mg500 MG100ug Lyophilized4 Sample Kit

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#32650289   2020/06/17 To Up

Training the next generation of radiopharmaceutical scientists.


Antony D Gee, Jan Andersson, Rajiv Bhalla, Yearn Seong Choe, David W Dick, Matthias M Herth, Eric D Hostetler, Ulises J Jáuregui-Haza, Ya-Yao Huang, Michelle L James, Jae Min Jeong, Aruna Korde, Yuji Kuge, Hank F Kung, Suzanne E Lapi, Joao Alberto Osso, Ephraim Parent, Marianne Patt, Ekoume Fany Pricile, Patrick J Riss, Ralph Santos-Oliveira, Stephen Taylor, Neil Vasdev, Johnny Vercouillie, Wolfgang Wadsak, Zhi Yang, Hua Zhu, Peter J H Scott

2612 related Products with: Training the next generation of radiopharmaceutical scientists.

100.00 ul96 Samplesmin 2 cartons200 units1 100 G500 Units11mg

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#32650285   2020/07/07 To Up

Talking about emotions: Effects of emotion-focused interviewing on children's physiological regulation of stress and discussion of the subjective elements of a stressful experience.

This is the first study to examine the effect of questioning children about emotions and cognitions versus facts on children's stress reactivity and regulation, as well as children's abilities to discuss their subjective experiences, in the context of adult-child discussions about a stressful event. A total of 80 8- to 12-year-old children participated in a stressful laboratory task (i.e., Trier Social Stress Test). Following the task, half of the children were engaged in an emotion-focused conversation with an adult interviewer about the event, and half were engaged in a fact-focused conversation. Electrodermal and cardiac preejection activity and respiratory sinus arrhythmia were derived at baseline, during the laboratory stressor, and during the conversation to index stress reactivity and regulation. Children's narratives were coded for indicators of emotion processing (i.e., positive and negative emotion words, cognitive words [e.g., think, know]). Children's English language abilities, self-reported stress, and several parent-report measures (demographics, child life stress, and children's emotion regulation strategies) were also obtained. Results indicate that the emotion-focused interview facilitated children's discussions of their subjective experiences without increasing their stress reactivity and that children showed enhanced physiological stress regulation during the emotion-focused interview. This research will be of interest to those in the fields of child narratives, stress, and social context as well as to parents and practitioners interested in improving children's understanding, reporting, and recovery after stressful experiences.
J Zoe Klemfuss, Erica D Musser

1784 related Products with: Talking about emotions: Effects of emotion-focused interviewing on children's physiological regulation of stress and discussion of the subjective elements of a stressful experience.

5 G50 ug 96T1 ml100ug 100 UG 100ul

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